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Many discarded donor kidneys could be used for transplantation

When researchers examined information on pairs of kidneys from the same donor in which 1 kidney was used but the other was discarded, the kidneys that were used tended to perform well even though they were similar in quality to their partner kidneys that were not used.

8 Dec 2017

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports.

6 Dec 2017

New mass-production platform overcomes barriers to bioengineering human liver tissues

Researchers report creating a biologically accurate mass-production platform that overcomes major barriers to bioengineering human liver tissues suitable for therapeutic transplant into people.

5 Dec 2017

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.

5 Dec 2017

Studies offer evidence that exercise alone can change composition of gut microbes

Two studies - one in mice and the other in human subjects - offer the first definitive evidence that exercise alone can change the composition of microbes in the gut. The studies were designed to isolate exercise-induced changes from other factors - such as diet or antibiotic use - that might alter the intestinal microbiota.

5 Dec 2017

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Hundreds of thousands of patients from newborns to the elderly are forced to grapple with the devastation of brain injury each year, and unlike many diseases where certain demographics are protected, brain injury can happen to anyone, anytime and anywhere.

4 Dec 2017

Study provides insights on mechanisms involved in tolerance after kidney transplantation

A new study provides insights on the mechanisms that allow an individual's immune system to accept, rather than reject, a donor kidney. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, point to markers that could be monitored to assess and track the health of organs following transplantation.

1 Dec 2017

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

UV radiation has been known for a long time to be a risk factor for the development of skin cancer. Simultaneous infection with human papillomaviruses (HPV) has also been suspected to promote skin cancer, particularly in organ transplant recipients.

30 Nov 2017

Scientists develop new technology to better study liver transplantation in pre-clinical setting

A team of scientists, physicians, and engineers from the Center for Engineering in Medicine and the Transplant Center of the Massachusetts General Hospital at the Harvard Medical School in Boston, MA reported the development of a new technology that enables researchers to better study liver transplantation in a pre-clinical setting.

29 Nov 2017

Capsule research could transform treatment for C. difficile infections

An Alberta-led clinical trial has shown Fecal Microbiota Transplant (FMT) is as effective in treating clostridium difficile (C. difficile) infections whether delivered by colonoscopy or by swallowing capsules.

28 Nov 2017

High levels of natural immune suppressor in leukemia patients linked to poor survival

Patients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most likely to die early, researchers say.

27 Nov 2017

High volume hospitals not necessarily better with heart valve surgeries

New research by UT Southwestern cardiologists counters long-held beliefs that hospitals performing greater numbers of heart valve surgeries have better outcomes.

23 Nov 2017

Drug could be repurposed to help end transplant rejection

A diabetes drug currently undergoing development could be repurposed to help end transplant rejection, without the side-effects of current immunosuppressive drugs, according to new research by Queen Mary University of London.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Pioneering research project aims to develop better diagnostic tests for NAFLD

A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring.

21 Nov 2017

Researchers find new way to boost cancer-destroying ability of T-cells

Researchers at Cardiff University have found a way to boost the cancer-destroying ability of the immune system's T-cells, offering new hope in the fight against a wide range of cancers.

20 Nov 2017

Slight changes to organ procurement system could increase number of kidney transplants

Slight changes to the system for allocating deceased-donor kidneys could result in higher rates of organ procurement and lead to more kidney transplants across the country, according to new research co-authored by an Indiana University Kelley School of Business professor.

17 Nov 2017

Breakthrough research brings new procedure closer to helping patients with blood cancer

A new procedure that can prevent the potentially lethal side effects of stem cell transplants is a step closer to helping more patients with blood cancers after a breakthrough in understanding of the key mechanism that makes it work.

17 Nov 2017

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

Two oxygen-producing compounds – including one that boosts performance in some laundry detergents – might one day play a key role in helping scientists successfully build a bioartificial pancreas in the lab to cure type 1 diabetes.

16 Nov 2017

ATS and JRS publish new guidelines for diagnosis and management of LAM

The American Thoracic Society and the Japanese Respiratory Society have published additional clinical practice guidelines regarding four specific questions related to the diagnosis of lymphangioleiomyomatosis (LAM) and management of pneumothoraces in patients with LAM.

15 Nov 2017

Transplant News and Research

Many discarded donor kidneys could be used for transplantation

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

New mass-production platform overcomes barriers to bioengineering human liver tissues

UT Southwestern researchers identify potential approach to suppress lethal parasitic infections

Studies offer evidence that exercise alone can change composition of gut microbes

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Study provides insights on mechanisms involved in tolerance after kidney transplantation

Papillomaviruses linked to UV light promote development of non-melanoma skin cancer

Scientists develop new technology to better study liver transplantation in pre-clinical setting

Capsule research could transform treatment for C. difficile infections

High levels of natural immune suppressor in leukemia patients linked to poor survival

High volume hospitals not necessarily better with heart valve surgeries

Drug could be repurposed to help end transplant rejection

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Pioneering research project aims to develop better diagnostic tests for NAFLD

Researchers find new way to boost cancer-destroying ability of T-cells

Slight changes to organ procurement system could increase number of kidney transplants

Breakthrough research brings new procedure closer to helping patients with blood cancer

Common ingredient in laundry detergents may help build bioartificial pancreas to cure type 1 diabetes

ATS and JRS publish new guidelines for diagnosis and management of LAM

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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