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Scientists discover a protein domain that could lead to new COVID-19 treatments

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

18 Apr 2023

New AI-based method for virtual staining of histopathological tissue samples

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium. Chemical staining has been the cornerstone of studying histopathology for more than a century and is widely applied in, for example, cancer diagnostics.

18 Apr 2023

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

17 Apr 2023

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

Antibiotics help to fight bacterial infections, but they can also harm the helpful microbes living in the gut, which can have long-lasting health consequences.

17 Apr 2023

Global novel disease surveillance: Majority of countries lack preparednes

Researchers explored national surveillance for new diseases in different countries.

15 Apr 2023

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

Researchers examined the effectiveness of SARS-CoV-2 booster doses in preventing severe Omicron infection outcomes.

15 Apr 2023

The neural mechanisms causing long-COVID fatigue

Researchers investigated the neural mechanisms underlying post-coronavirus disease fatigue.

14 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Researchers develop new approach for studying HBV in the lab

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded effective therapeutics.

13 Apr 2023

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

The current COVID-19 vaccines are designed to trigger an antibody response to the SARS-CoV-2 spike protein, which is vulnerable to mutations that could make the vaccine less effective over time.

13 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.

13 Apr 2023

Research highlights new technique for measuring cardiac risk related to cobalt-containing hip replacements

A technique for measuring the cardiac risk associated with cobalt-containing hip replacements has been highlighted for the first time in research at the University of Strathclyde.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

A recent article identifies the encephalitogenic viruses registered in Brazil over the past six decades.

12 Apr 2023

Nirmatrelvir-ritonavir reduces risk of post-COVID syndrome in non-hospitalized vaccinated patients

Researchers assess the effect of nirmatrelvir plus ritonavir on the occurrence of long COVID.

12 Apr 2023

Pediatric invasive group A Streptococcal infections on the rise during respiratory virus outbreak

Researchers assess the incidence of invasive Group A streptococcal infections among children before and after the COVID-19 pandemic.

12 Apr 2023

Machine learning methods may be effective in screening patients for sleep disorder risk

A machine learning model can effectively predict a patient's risk for a sleep disorder using demographic and lifestyle data, physical exam results and laboratory values, according to a new study published this week in the open-access journal PLOS ONE by Samuel Y. Huang of Virginia Commonwealth University School of Medicine, and Alexander A. Huang of Northwestern Feinberg University School of Medicine, US.

12 Apr 2023

New approach identifies significant molecular changes linked to pediatric bipolar disorder

It's extremely difficult to study the biological basis of psychiatric disorders, in part because researchers can't easily collect brain cells from living people to study in the laboratory. Now, University of Utah Health scientists have developed a way around that.

12 Apr 2023

Laboratory News and Research

Scientists discover a protein domain that could lead to new COVID-19 treatments

New AI-based method for virtual staining of histopathological tissue samples

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

Global novel disease surveillance: Majority of countries lack preparednes

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

The neural mechanisms causing long-COVID fatigue

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Researchers develop new approach for studying HBV in the lab

AI-designed T-cell vaccine extremely effective at preventing severe COVID-19 in mice

Curtin researchers identify the genetic signature of pre-malignant liver cells

Genomic study reveals Babesia duncani's pathogenicity and virulence

MHRA research evaluates two different approaches to cancer therapies

Research highlights new technique for measuring cardiac risk related to cobalt-containing hip replacements

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Thousands of unique arboviruses and flaviviruses identified from samples collected between 1954-2018

Nirmatrelvir-ritonavir reduces risk of post-COVID syndrome in non-hospitalized vaccinated patients

Pediatric invasive group A Streptococcal infections on the rise during respiratory virus outbreak

Machine learning methods may be effective in screening patients for sleep disorder risk

New approach identifies significant molecular changes linked to pediatric bipolar disorder

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