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New medical imaging technique

Researchers at Rensselaer are working to develop a new medical imaging technique designed to determine the relative stiffness of soft tissue for the diagnosis of injury and disease.

9 Aug 2004

Knowledge about oral and head and neck cancer is severely lacking in the American public

Most adult Americans know how to light a cigarette and order a drink, but a great number of them are clueless about the consequence of these two destructive habits – oral and head and neck cancer.

9 Aug 2004

Alterations in a tumor suppressor gene called p53 are more prevalent in breast cancer of African-American women than white women

Ethnic differences in the incidence and mortality rates of breast cancer are noted in the United States and worldwide. In the U.S., the most apparent differences are seen between African-American and white women. African-American women have lower incidence rates of the disease, but have higher mortality rates. Moreover, African-American women present at a younger age and with more aggressive disease.

9 Aug 2004

Many U.S. surgeons are not doing adequate numbers of operations for primary breast cancer to optimize patient survival

The study, published August 9, 2004 in the online edition of CANCER, a peer-reviewed journal of the American Cancer Society, demonstrates that fewer surgeries per year negatively impacted patient standard of care. A free abstract of the study is available at CANCER Online.

9 Aug 2004

New fluorescent dye technique may provide new insight into how cancerous tumors begin and grow

A technique developed by University of California, San Diego biologists, which uses bright fluorescent dyes to reveal the activity of genes in individual cells of an organism, promises to be a boon to developmental biologists, and may provide new insight into how cancerous tumors begin and grow.

6 Aug 2004

Physicians offer several promising and unique approaches to brain tumor treatment

An estimated 41,000 new cases of primary brain tumors are expected to be diagnosed in 2004, according to the American Brain Tumor Association.

5 Aug 2004

First evidence of the molecular link between inflammation and cancer

The investigators found that a gene called I-kappa-B kinase (IKK beta), a pro-inflammatory gene, acts differently in two cell types to cause cancer. When IKK beta was deleted, the cancer incidence and tumor growth in mice was decreased by nearly 80 percent.

5 Aug 2004

New gene-silencing technique

A new gene-silencing technique that takes place in the nucleus of human cells, has been demonstrated by researchers at the University of California, San Diego (UCSD) School of Medicine and the VA San Diego Healthcare System.

5 Aug 2004

Smart drug that targets cancer cells in the brain following removal of a tumor

The use of a "smart" drug that targets cancer cells in the brain following removal of a tumor may provide treatment that can extend the survival of people with the most common form of primary malignant brain tumor, glioblastoma multiforme (GBM).

3 Aug 2004

Successfully cloning mice from an advanced melanoma cell

Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute.

3 Aug 2004

Recommendation against the use of chemotherapy sensitivity and resistance assays

A new technology assessment from the American Society of Clinical Oncology states that the use of chemotherapy sensitivity and resistance assays (CSRAs) to select chemotherapeutic agents for cancer patients should not be undertaken outside of the clinical trial setting.

3 Aug 2004

Adhering to established guidelines improves survival and reduces the risk of breast cancer

The first study to compare survival between women with breast cancer whose treatment was based on consensus guidelines and those whose treatment was not shows that adhering to established guidelines improves survival and reduces the risk of recurrence.

3 Aug 2004

One-third of U.S. adults use some form of alternative medicine

More than one-third of U.S. adults use some form of alternative medicine such as herbal supplements and other therapies, showed in a nationwide survey by NIH's National Center for Complementary and Alternative Medicine published in May 2004.

2 Aug 2004

New approach to cancer vaccines may eradicate skin cancer tumors

Mayo Clinic and British researchers have developed a new approach to cancer vaccines that purposely kills healthy skin cells to target the immune system against tumors. The new approach has eradicated skin cancer tumors in mice.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Miniature spectroscopic instruments and software to look at changes that occur within the cells and tissue of the brain

When molecules in cells are stimulated by light, they respond by becoming excited and re-emitting light of varying colors (fluorescence) that can be captured and measured by highly sensitive optical equipment.

2 Aug 2004

The p53 transcription factor plays a vital role in preventing cancer onset

Researchers at the Uppsala Branch of the Ludwig Institute for Cancer Research have discovered that the transcription factor Yin Yang 1 (YY1) is a novel regulator of the tumor suppressor p53, which is inactivated in at least half of all human cancers.

2 Aug 2004

New surgical technique for larynx reconstruction

Professor Pierre Delaere (Otorhinolaryngology Department, K.U.Leuven) has in the past decade developed a new surgical technique for larynx reconstruction.

29 Jul 2004

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Eli Lilly and Company have announced that the Oncologic Drugs Advisory Committee (ODAC) of the U.S. Food and Drug Administration positively endorsed Alimta® (pemetrexed), an antifolate, for accelerated approval in the second-line treatment of non-small cell lung cancer.

29 Jul 2004

Combination of hormonal therapy, radioactive seed implant and external beam radiation therapy increases chance of cancer cure

High-risk prostate cancer patients who undergo a combination of hormonal therapy, radioactive seed implant (also called brachytherapy) and external beam radiation therapy are shown to have an increased chance of cancer cure

29 Jul 2004

Tumor News and Research

New medical imaging technique

Knowledge about oral and head and neck cancer is severely lacking in the American public

Alterations in a tumor suppressor gene called p53 are more prevalent in breast cancer of African-American women than white women

Many U.S. surgeons are not doing adequate numbers of operations for primary breast cancer to optimize patient survival

New fluorescent dye technique may provide new insight into how cancerous tumors begin and grow

Physicians offer several promising and unique approaches to brain tumor treatment

First evidence of the molecular link between inflammation and cancer

New gene-silencing technique

Smart drug that targets cancer cells in the brain following removal of a tumor

Successfully cloning mice from an advanced melanoma cell

Recommendation against the use of chemotherapy sensitivity and resistance assays

Adhering to established guidelines improves survival and reduces the risk of breast cancer

One-third of U.S. adults use some form of alternative medicine

New approach to cancer vaccines may eradicate skin cancer tumors

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Miniature spectroscopic instruments and software to look at changes that occur within the cells and tissue of the brain

The p53 transcription factor plays a vital role in preventing cancer onset

New surgical technique for larynx reconstruction

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Combination of hormonal therapy, radioactive seed implant and external beam radiation therapy increases chance of cancer cure

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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