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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Researchers explored the genetic variability among the monkeypox virus genomes of Clade IIb lineage B.1 using a phylodynamic and genetic survey to confirm the epidemic cluster in the clade and understand the evolution of the virus.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

DNA barcoding shows how cancer cells evade the immune system's defenses

Some cancer cells can deploy parallel mechanisms to evade the immune system's defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.

7 Nov 2022

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.

7 Nov 2022

Developing art and creativity to help fight cancer

Developing art and creativity to improve the effectiveness and delivery of healthcare. From narrative medicine to the disclosure of one's medical records on the net: how "open sourcing" feelings and fears can help fight cancer and reshape the concept of "cure".

4 Nov 2022

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

In this interview, Niall Dinwoodie, Executive Director for Gene Therapy for Charles River in Europe discusses the opening of their new HQ Plasmid Center of Excellence at Alderley Park.

From Charles Rivers Laboratories Cell and Gene Therapy 4 Nov 2022

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and -; similar to COVID-19 -; mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people.

4 Nov 2022

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Researchers generated and characterized two monoclonal antibodies (NA8 and NE12) that target the receptor binding domain of the SARS-CoV-2 spike protein, and exhibit neutralizing activity against major SARS-CoV-2 variants of concern.

3 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

The importance of accurate pipetting in biomedical laboratory work

In this interview, Stephanie Stursberg, Group Product Manager for pipetting platforms at INTEGRA Biosciences, talks to NewsMedical about the importance of accurate and efficient pipetting in biomedical laboratory work.

From INTEGRA Biosciences 2 Nov 2022

Molecular drug transporters could improve treatment of cancers and other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

High-throughput sequencing reveals structured olfactory neuron projections

Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses.

1 Nov 2022

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

DNA News and Research

Further Reading

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

DNA barcoding shows how cancer cells evade the immune system's defenses

Personalized whole genome sequencing approach could double the diagnostic rates of rare diseases

Developing art and creativity to help fight cancer

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

The importance of accurate pipetting in biomedical laboratory work

Molecular drug transporters could improve treatment of cancers and other diseases

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

High-throughput sequencing reveals structured olfactory neuron projections

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Study expands breast cancer patient population that can benefit from PARP inhibitors

Ancient genomes shed light on previously unknown aspect of human evolution

Lower risk of colorectal cancer associated with dietary flavanone and anthocyanidin intake, according to new research

Study finds increased antioxidant activity in citrus honey

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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