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$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

Pioneering cancer gene therapy gets green light — and $475,000 price tag

The country's first approved gene therapy — approved Wednesday to fight leukemia that resists standard therapies — will cost $475,000 for a one-time treatment, its manufacturer announced.

30 Aug 2017

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

Heat therapy may be a promising treatment in the fight against cancer, autoimmune problems and efforts to avoid organ rejection in transplant patients, according to researchers at the University of Kentucky.

30 Aug 2017

Immune booster could improve effectiveness of vaccines and cancer immunotherapy

Vaccines and cancer immunotherapies do essentially the same thing: They boost a person's immune system, better enabling it to fight an offender, be it microbe or malignancy.

29 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa clinical trial of a novel combination drug therapy for B-cell cancers.

26 Aug 2017

Vision research using donated human tissue could help millions suffering from diabetic eye disease

When Coleen Anegon's husband, Tim, received a liver donation as a patient at the University of Michigan in 2014, she immediately felt indebted to the donor who gave him the gift of life.

26 Aug 2017

Disease diagnostic tools win top honors in DEBUT challenge

Tools to diagnose Alzheimer's disease and latent tuberculosis are among the winning projects in the Design by Biomedical Undergraduate Teams (DEBUT) challenge, a biomedical engineering design prize competition for teams of undergraduate students.

26 Aug 2017

Rutgers University leadership creates great strides in breakthrough scientific research

Less than a decade ago, the U.S. Department of Defense established the Armed Forces Institute of Regenerative Medicine I with a multimillion dollar grant to focus research centered on regenerative medicine for the treatment of battlefield injuries and selected Rutgers University-New Brunswick to lead the civilian research program.

26 Aug 2017

What happens if you’re forced to switch health plans when you’re sick?

Joanna Joshua, 39, panicked when she opened a letter from her family's insurer, Cigna, only to learn it was pulling out of California's individual market next year.

26 Aug 2017

Study may lead to new therapy options for treatment resistant, relapsed endometrial cancer

A team of Cleveland Clinic researchers have discovered a key pathway that leads to recurrence and treatment resistance in endometrial cancer, providing the potential for much needed new therapies for women with limited options.

24 Aug 2017

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

Tiny packets of cells called islets throughout the pancreas allow the organ to produce insulin. Type 1 diabetes -- also known as juvenile diabetes - tricks the immune system into destroying these islets.

23 Aug 2017

Blood cleaning device can also effectively provide a bridge to liver transplantation

Severe acute liver failure (ALF), a rare but life-threatening illness, is associated with high death rates if patients don't receive timely treatment or a liver transplant.

23 Aug 2017

Our body contains more diverse microbes than previously known, new survey suggests

A new survey of DNA fragments circulating in human blood suggests our bodies contain vastly more diverse microbes than anyone previously understood.

23 Aug 2017

Research finds how omega-3 supplements dampen harmful inflammatory reactions

OMEGA-3: Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health.

23 Aug 2017

‘Breakthrough’ leukemia drug also portends ‘quantum leap’ in cost

When doctors talk about a new leukemia drug from Novartis, they ooze enthusiasm, using words like "breakthrough," "revolutionary" and "a watershed moment."

23 Aug 2017

New analysis explores promising strategies to increase living kidney donation

A new analysis indicates that few strategies to increase living kidney donation have been evaluated effectively; however, educational strategies targeted to recipients and their family and friends have the best evidence of being successful.

18 Aug 2017

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

The U.S. Food and Drug Administration (FDA) today approved Besponsa (inotuzumab ozogamicin) in the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL) - a rare form of ALL.

17 Aug 2017

$FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL$

FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL

The U.S. Food and Drug Administration today approved Besponsa (inotuzumab ozogamicin) for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).

17 Aug 2017

New synthetic antifreeze could make aeroplane wing design, organ transplants more effective

The design of aeroplane wings and storing organs for transplant could both become safer and more effective, thanks to a synthetic antifreeze which prevents the growth of ice crystals, developed by researchers at the University of Warwick.

17 Aug 2017

Transplant News and Research

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Pioneering cancer gene therapy gets green light — and $475,000 price tag

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

Immune booster could improve effectiveness of vaccines and cancer immunotherapy

Targeting bone marrow protein could be effective way to improve stem cell transplants

UC San Diego researchers receive $18.2 million grant for B cell cancer clinical trial

Vision research using donated human tissue could help millions suffering from diabetic eye disease

Disease diagnostic tools win top honors in DEBUT challenge

Rutgers University leadership creates great strides in breakthrough scientific research

What happens if you’re forced to switch health plans when you’re sick?

Study may lead to new therapy options for treatment resistant, relapsed endometrial cancer

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

Blood cleaning device can also effectively provide a bridge to liver transplantation

Our body contains more diverse microbes than previously known, new survey suggests

Research finds how omega-3 supplements dampen harmful inflammatory reactions

‘Breakthrough’ leukemia drug also portends ‘quantum leap’ in cost

New analysis explores promising strategies to increase living kidney donation

FDA approves Besponsa – Pfizer’s new drug for rare form of acute lymphoblastic leukemia

FDA approval provides new, targeted treatment option for adults with relapsed or refractory B-cell ALL

New synthetic antifreeze could make aeroplane wing design, organ transplants more effective

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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