Pharmaceuticals News and Research

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Startling results from new biomedical research will smooth path to the market place

Researchers have discovered how to convert liver cells of mice into pancreatic cells using a single injection. This may eventually lead to a cure for diabetes. Dr. James Mittra, one of the organisers of an international conference in Edinburgh on the Evolution of the Life Science Industries asks, “How does the pharmaceutical industry respond to this kind of work? They are primarily interested in treatments, not cures. Do they see this kind of research as a threat?”

27 Jan 2005

Enbrel to treat rheumatoid arthritis approved in Japan

Wyeth K.K. and Takeda Pharmaceutical Company Limited (Takeda) have announced that Enbrel (etanercept) has been approved by the Japan Ministry of Health, Labour and Welfare (MHLW) for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to existing therapies.

27 Jan 2005

Biochip for detection of inflammatory bowel disease

At the III International Symposium on Advanced Therapy for Chronic Inflammatory Bowel Disease, held in Madrid, the biotechnological company, Progenika, presented a DNA-chip the purpose of which is the optimisation of the diagnosis, prognosis and treatment of patients with inflammatory bowel disease (Crohn’s disease and Ulcerous Colitis).

26 Jan 2005

Tentative approval of co-packaged lamivudine/zidovudine fixed dose combination tablets and nevirapine tablets

The Food and Drug Administration (FDA) has announced the tentative approval of a co-packaged antiretroviral drug regimen manufactured by Aspen Pharmacare of South Africa for the treatment of HIV-1 infection in adults.

26 Jan 2005

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Currently, the limited efficacy of conventional therapies, especially in the case of several oncology and autoimmune and inflammatory disorders (AIID), is creating the need for safe and effective treatment alternatives.

25 Jan 2005

Launch date announced for Abraxane to treat metastatic breast cancer

American Pharmaceutical Partners announced today that February 8, 2005 is the launch date of Abraxane for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound). Abraxane will be marketed by the national sales force of Abraxis Oncology, APP's proprietary sales and marketing division.

25 Jan 2005

Plant protein mimics hormone that mitigates diabetes and obesity

A common protein that protects plants from fungal infection mimics the activity of a hormone in mammals that is linked to weight loss and is believed to play a role in mitigating heart disease, obesity and diabetes, according to a team of researchers at Purdue University and several collaborating institutions.

25 Jan 2005

Vioxx could have caused 140000 excess cases of coronary heart disease in the USA since 1999

The arthritis drug Vioxx could have caused an estimated 88 000–140 000 excess cases of serious coronary heart disease in the USA since its launch in 1999, concludes a study published online by The Lancet.

24 Jan 2005

More studies on risks and benefits of COX-2 inhibitors

A group of studies published in the January 24 issue of Archives of Internal Medicine add to the growing body of medical literature about the cardiovascular risks that may be associated with the class of pain-relieving drugs known as COX-2 inhibitors.

24 Jan 2005

Orally ingested drug to help Type 2 diabetes sufferers

A new drug invented by Monash University researchers Paul Zimmet and Frank Ng could help Type 2 diabetes sufferers lower blood glucose levels and enhance the potency of insulin, with few side effects.

24 Jan 2005

Organon’s compound, Org 24448, selected to test efficacy of cognitive dysfunction in schizophrenia

The National Institute of Mental Health (NIMH) sponsored network called Treatment Units for Research on Neurocognition in Schizophrenia (TURNS) has selected Organon’s compound, Org 24448, to undergo testing as part of its effort to facilitate the development of medications to enhance cognition in patients with schizophrenia.

24 Jan 2005

Health authorities reviewing scientific data from trials evaluating Alzheimer's treatment, Reminyl

Johnson & Johnson Pharmaceutical Research & Development, LLC (J&JPRD) announced that health authorities are reviewing scientific data from two clinical trials evaluating an investigational use of the company's Alzheimer's treatment, Reminyl (galantamine hydrobromide), in individuals with mild cognitive impairment.

24 Jan 2005

Anti-bacterial additive triclocarban widespread In U.S. waterways

Many rivers and streams in the United States are believed to contain a toxic antimicrobial chemical whose environmental fate was never thoroughly scrutinized despite large scale production and usage for almost half a century, according to an analysis conducted by researchers at the Johns Hopkins Bloomberg School of Public Health.

24 Jan 2005

Non-invasive fingertip test can identify coronary disease at its earliest stages

A non-invasive fingertip test can identify coronary disease at its earliest stages and may provide an easy to use tool for daily clinical practice, according to a recent study published in the Journal of the American College of Cardiology.

20 Jan 2005

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

Physicians are challenged in treating heart patients who may be at high-risk for gastrointestinal bleeding from aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Factors that place patients at high-risk include a history of ulcers or gastrointestinal complications such as bleeding, increased age and congestive heart failure.

20 Jan 2005

FDA knocks back anticancer drug Marqibo

Inex Pharmaceuticals announced today that United States Food and Drug Administration (FDA) provided an action letter detailing that the anticancer drug Marqibo (vincristine sulfate liposomes injection) is "not approvable" under the FDA's accelerated approval regulations based on the phase 2 clinical trial data submitted.

19 Jan 2005

Pharmaceuticals News and Research

Startling results from new biomedical research will smooth path to the market place

Enbrel to treat rheumatoid arthritis approved in Japan

Biochip for detection of inflammatory bowel disease

Tentative approval of co-packaged lamivudine/zidovudine fixed dose combination tablets and nevirapine tablets

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Launch date announced for Abraxane to treat metastatic breast cancer

Plant protein mimics hormone that mitigates diabetes and obesity

Vioxx could have caused 140000 excess cases of coronary heart disease in the USA since 1999

More studies on risks and benefits of COX-2 inhibitors

Orally ingested drug to help Type 2 diabetes sufferers

Organon’s compound, Org 24448, selected to test efficacy of cognitive dysfunction in schizophrenia

Health authorities reviewing scientific data from trials evaluating Alzheimer's treatment, Reminyl

Anti-bacterial additive triclocarban widespread In U.S. waterways

Non-invasive fingertip test can identify coronary disease at its earliest stages

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

FDA knocks back anticancer drug Marqibo

Major European research initiative in the genetics of drug addiction

More data needed on what's effective for hot flashes

Alvesco now available for asthma sufferers in the United Kingdom

Biopharmaceutical market generated revenues of USD 45.0 billion in 2004

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