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New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023

Legal questions, inquiries intensify around Noble Health’s rural Missouri hospital closures

A year after private equity-backed Noble Health shuttered two rural Missouri hospitals, patients and former employees grapple with a broken local health system or missing out on millions in unpaid wages and benefits.

23 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

Study discovers a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers.

22 Mar 2023

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2000 to 5000 people worldwide.

22 Mar 2023

New encoding strategy for single-cell tomograms streamlines data handling and storage

Single-cell analysis is a powerful biomedical technique used in various fields of biology and medicine to identify rare cell populations, track cell development and differentiation, understand disease mechanisms and develop personalized therapies, but it generates large amounts of data that can be difficult to manage.

22 Mar 2023

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2.

21 Mar 2023

Supervised exercise training is safe and may improve quality of life for many people with heart failure

For many people who have heart failure, supervised exercise training is safe and may offer substantial improvement in exercise capacity and quality of life, even more than medications, according to a new, joint scientific statement from the American Heart Association and the American College of Cardiology.

21 Mar 2023

Machine learning programs use routinely collected hospital data to predict risk of death

If you've ever been admitted to hospital or visited an emergency department, you've likely had an electrocardiogram, or ECG, a standard test involving tiny electrodes taped to your chest that checks your heart's rhythm and electrical activity.

21 Mar 2023

ACTG publishes study to simplify the administration of hepatitis C treatment

The AIDS Clinical Trials Group, the world's largest HIV research network, is announcing the publication of "Perspectives on Adherence from the ACTG 5360 MINMON Trial: A Minimum Monitoring Approach with 12 Weeks of Sofosbuvir/Velpatasvir in Chronic Hepatitis C Treatment" in the journal Clinical Infectious Diseases.

21 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Playing tackle football at an early age increases risk for brain decline later

The degenerative brain disease known as CTE, or chronic traumatic encephalopathy, has become a specter haunting football.

20 Mar 2023

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway.

20 Mar 2023

New model could make the measurement of skin barrier function easier

The skin is the primary physical barrier against harmful substances in the environment. But there is a significant difference in the protective capacity of the skin across individuals.

20 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

Machine learning applications for the diagnosis, treatment and prognosis of cancer

Researchers review the application of machine learning in improving cancer diagnosis, treatment, and prognosis.

19 Mar 2023

Researchers find new way to remove waste after brain hemorrhage

University of Helsinki and Taiwanese researchers have found a new way to remove waste from the brain after hemorrhage.

17 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

Laboratory News and Research

New discovery could help target the causes of aging and cancer development

Legal questions, inquiries intensify around Noble Health’s rural Missouri hospital closures

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Study discovers a protein controlling resistance to chemotherapy

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

New encoding strategy for single-cell tomograms streamlines data handling and storage

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Supervised exercise training is safe and may improve quality of life for many people with heart failure

Machine learning programs use routinely collected hospital data to predict risk of death

ACTG publishes study to simplify the administration of hepatitis C treatment

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

AI-based design method synthesizes polymers that mimic blood plasma

Playing tackle football at an early age increases risk for brain decline later

Research shows the role of PCYT2-mediated lipid synthesis in vertebrate muscle health

New model could make the measurement of skin barrier function easier

Upgraded tumor model points the way toward more effective cancer therapies

Machine learning applications for the diagnosis, treatment and prognosis of cancer

Researchers find new way to remove waste after brain hemorrhage

Scientists develop a marker for therapy response in acute myeloid leukemia

Designer DNA drug could be used to delay paralysis in ALS

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