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Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

The molecule CD103 is key to the long-term residence of T cells in the skin and to their anti-tumor function, report a team of researchers at the Medical University of South Carolina and the Dartmouth-Hitchcock Norris Cotton Cancer Center In the April 14, 2017, Science Immunology.

28 Apr 2017

Fecal microbiota transplant may be effective treatment option for ulcerative colitis, research suggests

A single transplant of microbes contained in the stool of a healthy donor is a safe and effective way to increase diversity of good bacteria in the guts of patients with ulcerative colitis, according to new research from Weill Cornell Medicine and NewYork-Presbyterian.

27 Apr 2017

Findings could lead to new treatments for people who overdose on popular pain reliever

Results from a new study show that after an acetaminophen overdose the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself.

27 Apr 2017

Researchers take important step toward using transplanted fetal cells to treat liver failure

In a new study, researchers demonstrate successful transplantation of fetal rat liver cells to an injured adult rat liver. The work is an important step toward using transplanted cells to treat liver failure, which currently requires an organ transplant.

26 Apr 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Scientists reveal unexpected route to slow progression of diabetic kidney disease

More than 660,000 people in the United States suffer from end-stage kidney disease, which can only be treated by dialysis or kidney transplantation. Almost half of these patients develop the condition as a complication of diabetes.

25 Apr 2017

Researchers aim to develop machine-learning method to better predict risks of organ donation

Organ transplants are a game of odds. Success depends on a number of factors: how old and how healthy the donor is, how old and how healthy the recipient is, how good a biological match can be found, how ready the patient is to receive it.

24 Apr 2017

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.

24 Apr 2017

Researchers identify obesity as leading cause of preventable life-years lost

A team of researchers from Cleveland Clinic and New York University School of Medicine have found that obesity resulted in as much as 47 percent more life-years lost than tobacco, and tobacco caused similar life-years lost as high blood pressure.

24 Apr 2017

Analysis finds high infection rates with contact lens than with LASIK to correct vision

Which causes fewer eye infections - contact lens wear or LASIK surgery? While traditionally contacts were thought to be safer than a surgical procedure, an analysis by ophthalmologists from the Hamilton Eye Institute at the University of Tennessee Health Science Center indicates otherwise.

21 Apr 2017

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

21 Apr 2017

Mice study yields important clues about protective role of Clostridia strains

Hundreds of thousands of babies worldwide die every year from infections that ravage their digestive systems – including those caused by Salmonella and E. coli bacteria. Millions more get sick.

21 Apr 2017

Global Kidney Health Atlas highlights huge gaps in CKD care and prevention

Despite one in 10 people worldwide having chronic kidney disease, a new global report - The Global Kidney Health Atlas - presented at this week's World Congress of Nephrology in Mexico City and compiled by the International Society of Nephrology and kidney health experts worldwide and published in JAMA- highlights the huge gaps in kidney disease care and prevention in both developed and developing countries, with many countries not prioritising kidney health.

21 Apr 2017

New model may provide vital insights into life-saving treatment for CMV infection

At-risk patients, such as those with HIV or transplant recipients, could benefit from potentially life-saving study carried out by a University of Surrey led group of international researchers.

21 Apr 2017

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.

18 Apr 2017

3D-printed phantom of stenotic intracranial artery helps standardize vessel-wall MRI protocols

A collaboration between stroke neurologists at the Medical University of South Carolina and bioengineers at the University of Massachusetts has led to the creation of a realistic, 3D-printed phantom of a stenotic intracranial artery that is being used to standardize protocols for high-resolution MRI, also known as vessel-wall MRI, at a network of U.S. and Chinese institutions, according to an article published online March 9, 2017 by the Journal of NeuroInterventional Surgery.

17 Apr 2017

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.

12 Apr 2017

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Adult patients with sickle cell disease (SCD) who experience a stroke caused by a clot (i.e., ischemic strokes or IS) can be treated safely with tissue plasminogen activator (tPA) if they qualify, report investigators at the Medical University of South Carolina and elsewhere in the March 2017 issue of Stroke.

12 Apr 2017

Study explores health and function of cortical neurons in hand amputees

Researchers have found that the nerve cells (neurons) controlling sensation and movement of the hands show injury-induced changes for years after hand amputation, reattachment or transplant.

11 Apr 2017

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell development.

10 Apr 2017

Transplant News and Research

Researchers show resident T cells in the skin depend on CD103 molecule for their anti-tumor function

Fecal microbiota transplant may be effective treatment option for ulcerative colitis, research suggests

Findings could lead to new treatments for people who overdose on popular pain reliever

Researchers take important step toward using transplanted fetal cells to treat liver failure

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Scientists reveal unexpected route to slow progression of diabetic kidney disease

Researchers aim to develop machine-learning method to better predict risks of organ donation

Testing for molecular markers in urine could reveal early signs of kidney transplant failure

Researchers identify obesity as leading cause of preventable life-years lost

Analysis finds high infection rates with contact lens than with LASIK to correct vision

High-fat diet and obesity drive liver immune cells to promote metabolic syndrome

Mice study yields important clues about protective role of Clostridia strains

Global Kidney Health Atlas highlights huge gaps in CKD care and prevention

New model may provide vital insights into life-saving treatment for CMV infection

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

3D-printed phantom of stenotic intracranial artery helps standardize vessel-wall MRI protocols

Researchers identify three novel genetic mutations linked to Fuchs dystrophy

MUSC researchers provide first systemic evidence for safe use of tPA in stroke patients with SCD

Study explores health and function of cortical neurons in hand amputees

Scientists use time-lapse video to identify cells that trigger blood stem cell development

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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