Immune System News and Research

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A convergent mechanism for two top-ranking risk genes may be responsible for ASD/ID

University at Buffalo scientists have discovered a convergent mechanism that may be responsible for how two top-ranked genetic risk factors for autism spectrum disorder/intellectual disability (ASD/ID) lead to these neurodevelopmental disorders.

1 Jul 2022

Nomogram helps predict anal cancer risk in HIV patients

Both cervical and anal cancer are caused by human papillomavirus. Both diseases also share a common precursor: abnormal cells known as high-grade squamous intraepithelial lesions (HSIL).

1 Jul 2022

Stopping a pervasive bacterium that makes millions sick each year

As we head outdoors this summer, scientists are working to clip the long, flexible appendages that enable the common bacterium Campylobacter jejuni to make its way from undercooked poultry and natural waterways into our intestinal tract where it makes millions of us sick each year.

1 Jul 2022

AAP recommends breastfeeding for 2 years

The American Academy of Pediatrics recommends that mothers to continue breastfeeding for two years or beyond.

30 Jun 2022

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

A new study found that the post-COVID-19 functional remodeling of T cells occurs in two steps and confers different convalescent immune states, six months after SARS-CoV-2 infection.

30 Jun 2022

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

Scientists exploring how our immune system responds to pathogens and cancers have ramped up their attention to CD8+ T cells, which are deployed in response to infections and malignancies and equipped to remember the identities of malicious invaders.

29 Jun 2022

COVID-19 pandemic linked to lower antibodies in breastmilk

New research describes the results of a study measuring such protection and exploring the effects of waning antibody levels on infant susceptibility to respiratory pathogens.

29 Jun 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

Memory B cells can be localized in the lungs, research shows

How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

28 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Healthy Black and Hispanic adolescents found to have low vitamin D levels

Results from a University of Houston College of Nursing study indicate that 61% of otherwise healthy Black and Hispanic adolescents have low vitamin D levels, that drop even lower with age.

28 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland.

28 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

Mother's gut microbes can aid in the healthy development of baby, finds study

Researchers studying mice have found the first evidence of how a mother's gut microbes can help in the development of the placenta, and the healthy growth of the baby.

28 Jun 2022

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.

28 Jun 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

Immune System News and Research

A convergent mechanism for two top-ranking risk genes may be responsible for ASD/ID

Nomogram helps predict anal cancer risk in HIV patients

Stopping a pervasive bacterium that makes millions sick each year

AAP recommends breastfeeding for 2 years

Study shows long COVID remodeling of T cell dynamics is dependent on SARS-CoV-2 severity

Study provides a framework for understanding how tissue-resident memory T cells adapt to distinct environments

COVID-19 pandemic linked to lower antibodies in breastmilk

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Investigating the prerequisites for developing RNA-based antibiotics

Memory B cells can be localized in the lungs, research shows

New study looks at the role of beta cells in triggering autoimmunity

Analysis finds variation in the management of mantle cell lymphoma across clinical settings

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Healthy Black and Hispanic adolescents found to have low vitamin D levels

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

Phase 1 clinical trial of new influenza vaccine begins at NIH Clinical Center in Bethesda

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

Mother's gut microbes can aid in the healthy development of baby, finds study

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

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