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Study finds link between tumor microbiome and immune system in sarcoma patients

In a significant new study, UC Davis Comprehensive Cancer Center researchers have uncovered a link between a patient's microbiome and their immune system that can potentially be used to improve the treatment of soft tissue sarcoma.

30 Jan 2023

New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

Combating Alzheimer's and other neurodegenerative diseases by inserting healthy new immune cells into the brain has taken a leap toward reality.

30 Jan 2023

Novel class of sulfonamides to block malaria transmission

Malaria is a devastating disease, with 247 million cases and 619,000 deaths reported in 2021 alone. Malaria causes fever and a flu-like illness that occurs when people are infected with the parasite Plasmodium falciparum, which is spread by mosquitoes.

30 Jan 2023

A neural interface to detect and alleviate symptoms of neurological disorders

EPFL researchers have combined low-power chip design, machine learning algorithms, and soft implantable electrodes to produce a neural interface that can identify and suppress symptoms of various neurological disorders.

30 Jan 2023

Third booster dose of SARS-CoV-2 vaccine associated with 90% reduction in COVID-19 deaths

A booster (third) dose of a SARS-CoV-2 vaccine was associated with a 90% reduction in death in people with multiple health conditions compared to 2 doses, according to a new study from Hong Kong published in CMAJ.

30 Jan 2023

A wearable ultrasound sensor provides real-time cardiac imaging

In a recent article published in the journal Nature, a team of researchers described a wearable ultrasonic device that allows cardiac function to be assessed directly in real-time, with improved coupling between human skin and the device, making the examination of the left ventricle during motion possible from different views.

29 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Autistic individuals experience pain at a higher intensity than general population, study finds

A new study has examined the pain perception among people with autism and found that they experience pain at a higher intensity than the general population and are less adaptable to the sensation.

29 Jan 2023

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

The vital role of oxytocin-;the "love hormone"-;for social attachments is being called into question. More than forty years of pharmacological and behavioral research has pointed to oxytocin receptor signaling as an essential pathway for the development of social behaviors in prairie voles, humans, and other species, but a genetic study publishing in the journal Neuron on January 27 shows that voles can form enduring attachments with mates and provide parental care without oxytocin receptor signaling.

29 Jan 2023

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Under the supervision of four professors from the UMCG departments of Gastroenterology and Hepatology and Pathology and Medical Biology, Bourgonje conducted doctoral research on the predictive value of biomarkers for inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

29 Jan 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

DePaul University and Rosalind Franklin University of Science and Medicine are funding three faculty research projects that bring together artificial intelligence, biomedical discovery and health care.

27 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Researchers identify an unexpected driver of cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells.

27 Jan 2023

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide.

27 Jan 2023

Novel research studies move closer to predicting two important heart conditions

Two novel research studies from Cedars-Sinai move the needle on predicting two important heart conditions-; sudden cardiac arrest, which is often fatal, and increased coronary artery calcium, a marker of coronary artery disease that can lead to a heart attack.

26 Jan 2023

Gratitude has a unique stress-buffering effect, research shows

More thankful, less stressed? Researchers from Irish universities carried out a study with 68 adults and found that gratitude has a unique stress-buffering effect on both reactions to and recovery from acute psychological stress, which can contribute to the improvement of cardiovascular health.

26 Jan 2023

Study reveals why hypoglycemic episodes worsen diabetic retinopathy

People with diabetes who experience periods of low blood sugar — a common occurrence in those new to blood sugar management — are more likely to have worsening diabetic eye disease.

26 Jan 2023

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

A team of investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has shown for the first time that a combination of targeted therapies with immunotherapy addresses one of the major reasons pancreatic cancer is so notoriously treatment resistant.

26 Jan 2023

Caron Receives Patents for Humanity COVID-19 Program Award from the United States Patent and Trademark Office

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26 Jan 2023

Laboratory News and Research

Study finds link between tumor microbiome and immune system in sarcoma patients

New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

Novel class of sulfonamides to block malaria transmission

A neural interface to detect and alleviate symptoms of neurological disorders

Third booster dose of SARS-CoV-2 vaccine associated with 90% reduction in COVID-19 deaths

A wearable ultrasound sensor provides real-time cardiac imaging

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Autistic individuals experience pain at a higher intensity than general population, study finds

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

Activated neutrophils can become potent cancer fighters

Researchers identify an unexpected driver of cancer immunotherapy resistance

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Novel research studies move closer to predicting two important heart conditions

Gratitude has a unique stress-buffering effect, research shows

Study reveals why hypoglycemic episodes worsen diabetic retinopathy

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

Caron Receives Patents for Humanity COVID-19 Program Award from the United States Patent and Trademark Office

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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