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Report highlights the need for an office to support autoimmune disease research across NIH institutes

While the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimmune diseases is impressive, a strategic plan and a well-funded office to support the coordination of all autoimmune disease research across NIH institutes and centers are needed, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

10 May 2022

Fluorescent probe can track how tumors respond to drugs

Researchers say the fluorescent probe can track how tumours are responding to the drugs, which harness the body’s immune system to fight disease.

10 May 2022

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease.

10 May 2022

Breastfeeding associated with improved maternal mental health outcomes

Scientists from the University of Massachusetts, USA, have recently found that breastfeeding is associated with improved maternal mental health overall.

10 May 2022

Severe symptoms result in high titers of SARS-CoV-2 antibodies

Scientists have focused on determining the cause-effect relationship between SARS-CoV-2 antibody titers and COVID-19 disease severity.

9 May 2022

LJI researchers uncover new drug target for severe asthma, lung fibrosis

If you've ever struggled to breathe, you've had a moment of hypoxia-;a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult."

9 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

New genetic markers could improve early detection of drug-resistant tuberculosis

To many, tuberculosis (TB) may seem like a disease from a bygone era. But it still claims more than one million lives every year.

9 May 2022

Differences in COVID-19 outcomes related to sex

Researchers looked at gender variations in COVID-19 outcomes such as hospitalization, ICU admission, mortality, and heart damage.

9 May 2022

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Your immune system's ability to combat COVID-19, like any infection, largely depends on its ability to replicate the immune cells effective at destroying the SARS-CoV-2 virus that causes the disease.

9 May 2022

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

6 May 2022

Study reveals why some lungs are protected against COVID

COVID-19 vaccines have saved at least a million lives in the United States alone, but for many people, a lingering fear remains: if-;or when-;they get hit by the coronavirus, just how bad will it be? Will they breeze through with little more than a sore throat-;or will it saddle them with long-term complications, perhaps even push them to the brink of death?

6 May 2022

Potential antiviral targets in SARS-CoV-2

Researchers assessed potential targets in severe acute respiratory syndrome coronavirus 2.

6 May 2022

Is type 1 diabetes likely to rise after the COVID pandemic?

A recent article posted to the journal Diabetes/Metabolism Research and Reviews explored the risk of a type 1 diabetes wave after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

6 May 2022

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset of type 1 diabetes.

6 May 2022

Crucial discovery could inform potential strategies to control malaria transmission

WEHI researchers in Melbourne have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes.

5 May 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

5 May 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

Immune System News and Research

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Fluorescent probe can track how tumors respond to drugs

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Breastfeeding associated with improved maternal mental health outcomes

Severe symptoms result in high titers of SARS-CoV-2 antibodies

LJI researchers uncover new drug target for severe asthma, lung fibrosis

T cell behavior informs metastatic melanoma outcomes

Study identifies interleukin-6 as a potential target in refining cancer therapies

New genetic markers could improve early detection of drug-resistant tuberculosis

Differences in COVID-19 outcomes related to sex

COVID-19 mortality among elderly may be due to genetically predetermined limit on the immune system

Antigen-presenting cancer-associated fibroblasts offer a new target to fight pancreatic cancer

Study reveals why some lungs are protected against COVID

Potential antiviral targets in SARS-CoV-2

Is type 1 diabetes likely to rise after the COVID pandemic?

Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs

Crucial discovery could inform potential strategies to control malaria transmission

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

Fecal microbiota transplant can reverse hallmarks of aging in mice

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