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Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Chemists from the University of Groningen have found a simple way to produce previously inaccessible chiral Z-alkenes, molecules that offer a significant synthetic short-cut for the production of bioactive molecules.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

Altering a cellular process can lead stem cells to die or regenerate, study finds

A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead stem cells-;cells from which other cells in the body develop-;to die or regenerate.

13 Jan 2023

“Zone of uncertainty” communicates with the neocortex to rapidly control memory formation

The neocortex is the largest and most complex part of the brain and has long been considered the ultimate storage site for long-term memories. But how are traces of past events and experiences laid down there?

13 Jan 2023

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

A recent study evaluated outcomes in mechanically ventilated patients with pneumonia due to COVID-19 or other etiologies.

13 Jan 2023

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Scientists from The Australian National University and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

13 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

Discovery of a potential new target for new MPOX or broad pox vaccines

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and identification of antigens of MPXV IIa clade and IIb clade, in comparison to recipients of smallpox vaccines (ACAM2000 and IMVANEX).

12 Jan 2023

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether commensal rodent pests such as rats and mice, sourced from sewers and urban settings, are exposed to and are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They also investigated viruses present in commensal rodents.

12 Jan 2023

American Cancer Society's annual report on cancer facts and trends released

Today, the American Cancer Society released Cancer Statistics, 2023, the organization's annual report on cancer facts and trends. According to the report, overall cancer mortality has dropped 33% since 1991, averting an estimated 3.8 million cancer deaths.

12 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines -; the so-called gut microbiome -; have far-reaching effects on how our bodies function.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

How might healthcare transform in the next 50 years?

A new study published in Futures highlighted key factors likely to influence the evolution of medicine over the next 50 years. These factors included wellness technologies, data-driven personalization, and climate change.

12 Jan 2023

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

New research in the January 2023 issue of JNCCN-;Journal of the National Comprehensive Cancer Network finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).

12 Jan 2023

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park.

From BioGrad 12 Jan 2023

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Announcing a new publication for Acta Materia Medica journal. The objective of this study was to systematically evaluate the clinical efficacy of the complementary use of corticosteroids in the treatment of community-acquired pneumonia (CAP).

11 Jan 2023

Study on bacterial infection in older individuals

The older population is prone to microbial infections, which can lead to death. Hence, it is important to understand why this group is vulnerable to microbial infection, especially bacterial infection. A recent Scientific Reports study linked data from two sources to understand the determining factors for microbial infection in the older population in the UK.

11 Jan 2023

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop.

11 Jan 2023

Laboratory News and Research

Chemists find a simple way to produce previously inaccessible chiral Z-alkenes

Valuable tool reveals the connections between gut microbes and the brain

Altering a cellular process can lead stem cells to die or regenerate, study finds

“Zone of uncertainty” communicates with the neocortex to rapidly control memory formation

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

New cooling strategy could prevent the growth of glioblastoma

Discovery of a potential new target for new MPOX or broad pox vaccines

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

American Cancer Society's annual report on cancer facts and trends released

New technique could overcome the delivery hurdles faced by promising mRNA therapies

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

Unique mass spectrometry-based approach to study specific changes in DNA after replication

How might healthcare transform in the next 50 years?

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Study on bacterial infection in older individuals

Rethinking next generation of improved vaccines for mucosa-replicating viruses

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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