Immune System News and Research

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SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

A recent study posted to the bioRxiv* preprint server demonstrated that the latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages evade immunity imparted by the prior subvariants.

5 May 2022

New study helps explain the immune system’s response to skin infections and skin cancers

It is well established that older adults are more susceptible to infection and their immune systems less capable of generating a strong immune response.

4 May 2022

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.

4 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

Green walls inside offices diversify employees’ skin microbiota, study shows

The experimental study led by the Natural Resources Institute Finland (Luke) showed that air-circulating green walls installed inside offices modified microbiota affecting employees’ skin health and enhanced the immune system’s regulation. Effects could already be seen during one month.

3 May 2022

Study: Cognitive deficit in COVID-19 survivors is equivalent to 20 years of aging

Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, say a team of scientists from the University of Cambridge and Imperial College London.

3 May 2022

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

People with lupus have overactive immune systems that attack their own tissue, causing inflammation throughout the body.

3 May 2022

Study uncovers blood clotting and immune protein pathways impacted in children with severe COVID-19

Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments.

3 May 2022

$6 million grant to fund research investigating the role of immune system in heart failure

A new grant for researchers at Washington University School of Medicine in St. Louis will fund research investigating the role of the immune system in heart failure. Finding ways to harness beneficial immune cells could lead to new therapies that encourage the heart to heal after injuries.

2 May 2022

Antibiotics may disrupt microbiome to cause recurrent UTIs

A study by researchers at Washington University School of Medicine in St. Louis and the Broad Institute of MIT and Harvard suggests that women who get recurrent urinary tract infections (UTIs) may be caught in a vicious cycle in which antibiotics given to eradicate one infection predispose them to develop another.

2 May 2022

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

When a patient in the pediatric intensive care unit (PICU) develops a fever, physicians often routinely order a blood culture to identify the cause, particularly if they have reason to worry about sepsis, a life-threatening condition that occurs when chemicals released by immune system cells in the bloodstream to fight an infection trigger inflammation and shock throughout the body.

2 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Artificial circular RNAs found to bypass cellular antiviral responses

Researchers produced artificial circular ribonucleic acid sponges in a permuted intron-exon system and showed that these did not activate innate immunity.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Improving Medical Communication through Social Media

News-Medical interviews Dr. Benjamin Schmidt about using social media to highlight different perspectives in the medical community and improve communication between patients and doctors.

29 Apr 2022

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

All humans carry genetic variations in their DNA, called Single Nucleotide Polymorphisms (SNPs) that can underlie susceptibility to diseases such as diabetes and cancer.

28 Apr 2022

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

A new study from North Carolina State University examines immune system diversity in the critically endangered Wyoming toad and finds that genetic bottlenecks could impact a species' ability to respond to new pathogens.

28 Apr 2022

Yale researchers identify immune system culprit in severe COVID cases

Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Immune System News and Research

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

New study helps explain the immune system’s response to skin infections and skin cancers

Researchers reveal the mechanism of action of century-old BCG vaccine

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

Green walls inside offices diversify employees’ skin microbiota, study shows

Study: Cognitive deficit in COVID-19 survivors is equivalent to 20 years of aging

Normal-appearing skin of lupus patients predisposed to flares and rashes, study finds

Study uncovers blood clotting and immune protein pathways impacted in children with severe COVID-19

$6 million grant to fund research investigating the role of immune system in heart failure

Antibiotics may disrupt microbiome to cause recurrent UTIs

A “less is more” method may prevent antibiotic overuse in pediatric intensive care unit patients

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Artificial circular RNAs found to bypass cellular antiviral responses

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Improving Medical Communication through Social Media

New workflow identifies hidden genetic connections that could improve personalized medicine for IBD

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

Yale researchers identify immune system culprit in severe COVID cases

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

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