Genes News and Research

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Gene associated with susceptibility to developing type 1 diabetes

A new gene mutation identified by researchers at Baylor College of Medicine in Houston is part of the constellation of genes associated with susceptibility to developing type 1 diabetes. It could also play a role in the devastating complications of diabetes such as kidney failure.

23 Jul 2004

$1.6 million to develop gene therapy strategies for Duchenne muscular dystrophy, a fatal, childhood-onset disease

The Muscular Dystrophy Association has announced it has awarded $1.6 million to Asklepios, a biotechnology company closely allied with the University of North Carolina at Chapel Hill, to develop gene therapy strategies for Duchenne muscular dystrophy (DMD), a fatal, childhood-onset disease.

23 Jul 2004

Surprising differences in the DNA of normal cells from different people

A new study by Michael Wigler’s group at Cold Spring Harbor Laboratory has, in collaboration with researchers from Karolinska Institutet, revealed surprising differences in the DNA of normal cells from different people.

23 Jul 2004

New DNA microarray to speed bone disease research

Velcura Therapeutics has announced the development of a custom Affymetrix GeneChip(R) array that aids the development of bone disease therapies by enabling researchers to follow global changes in gene expression during human bone formation.

23 Jul 2004

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

Finding cancer in a tiny drop of body fluid containing relatively few cells now may be possible with a new method of analyzing multiple genes in small samples of DNA, the cellular building blocks of our genetic code.

23 Jul 2004

New precautionary measures against the possible risk of transmission of variant Creutzfeldt Jakob Disease

The UK Department of Health (DOH) has said today that recipients of blood transfusions are to be excluded from donating blood in the future as a further precautionary measure against the possible risk of transmission of variant Creutzfeldt Jakob Disease (vCJD), Health Secretary John Reid announced today.

23 Jul 2004

Epilepsy, new therapeutic possibilities

To date epilepsy research has mainly concentrated on the transmission of the nerve cell signals to what are known as the synapses.

23 Jul 2004

Researchers discover a mechanism that blocks replication of a retrovirus

A team of scientists led by University of Georgia researchers has discovered a naturally occurring mechanism that blocks a critical step late in retrovirus replication.

21 Jul 2004

Chemotherapy aimed at both cancer cells and their genetically normal cellular 'microenvironment' might improve the success of breast cancer treatment

In the first comprehensive survey of gene activity in each cell type composing normal and malignant breast tissue, scientists at Dana-Farber Cancer Institute have identified genes in non-cancerous supporting cells that can spur the growth of breast cancer cells.

20 Jul 2004

U.S. scientists have found the genetic basis for one form of sudden infant death syndrome

Sudden infant death syndrome, also known as cot death and crib death, is defined as the death of an infant between the ages of one month and one year which remains unexplained after a thorough postmortem, investigation of the death scene and review of the clinical history.

20 Jul 2004

New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

DNA left overs, new mechanism for evolution

A team of researchers from the Universitat Autònoma de Barcelona (UAB) has discovered that transposons, small DNA sequences that travel through the genomes, can silence the genes adjacent to them by inducing a molecule called antisense RNA.

16 Jul 2004

8.5 million Euros to address a fundamental question on mitosis: How is cell division regulated?

Scientists at the European Molecular Biology Laboratory (EMBL) join forces with top scientists from eleven research institutes in Austria, Germany, Italy, France and the United Kingdom for “MitoCheck” – the largest integrated research project on cell cycle control within the European Commission’s 6th Framework Programme (FP6).

15 Jul 2004

Novel tool that can be used to visualize single neurons in living brain tissue

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

15 Jul 2004

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

Research may help predict risk for prostate cancer based on gene expression patterns

According to a study published in the July 15 issue of the Journal of Clinical Oncology, genes expressed in benign tissue adjacent to prostate cancer tissue are much more similar to those expressed in prostate cancer tissue than previously thought.

15 Jul 2004

New hereditary spastic paraplegia research

In work reported this week, researchers have taken our understanding of HSP to a new level with the development of an animal model for the disease.

13 Jul 2004

Molecular mechanisms behind XsalF's anterior specifying activity

Embryologists have long been interested in working out the means by which this regionalization is achieved, and for years the dominant theory has involved a two-step mechanism in which neural tissues are first induced lengthwise down the entire body axis, followed by a transformation step where a second signal specifies the posterior identities of the neural tissue

13 Jul 2004

Genetic mutation is a major contributor to type 1 diabetes

A natural mutation of a gene that helps regulate the reactivity of the immune system is a major contributor to type 1 diabetes, Medical College of Georgia researchers have found.

12 Jul 2004

DNAPrint significantly reduced the DNA donor sample collections required in a major criminal investigation

DNAPrint genomics, Inc. has announced that, according to the July 7, 2004 London Times article "1,000 men were asked to give DNA in hunt for serial rapist" by Madeleine Acey, "Detectives hunting one of Britain's worst serial sex attackers are inviting 1,000 men to provide DNA samples as they try to identify the rapist. Officers have narrowed down a list of possible suspects to 1,000 men who meet a geographical and racial profile. They started off with 10,000."

10 Jul 2004

Genes News and Research

Gene associated with susceptibility to developing type 1 diabetes

$1.6 million to develop gene therapy strategies for Duchenne muscular dystrophy, a fatal, childhood-onset disease

Surprising differences in the DNA of normal cells from different people

New DNA microarray to speed bone disease research

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

New precautionary measures against the possible risk of transmission of variant Creutzfeldt Jakob Disease

Epilepsy, new therapeutic possibilities

Researchers discover a mechanism that blocks replication of a retrovirus

Chemotherapy aimed at both cancer cells and their genetically normal cellular 'microenvironment' might improve the success of breast cancer treatment

U.S. scientists have found the genetic basis for one form of sudden infant death syndrome

New compound that is designed to overcome Gleevec resistance

DNA left overs, new mechanism for evolution

8.5 million Euros to address a fundamental question on mitosis: How is cell division regulated?

Novel tool that can be used to visualize single neurons in living brain tissue

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

Research may help predict risk for prostate cancer based on gene expression patterns

New hereditary spastic paraplegia research

Molecular mechanisms behind XsalF's anterior specifying activity

Genetic mutation is a major contributor to type 1 diabetes

DNAPrint significantly reduced the DNA donor sample collections required in a major criminal investigation

eBook: Using iPSCs models for human disease research and drug discovery eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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