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Next-generation sequencing could change research on sexual assault cases

In this interview, Alexis Garloff talks to NewsMedical about her next-generation sequencing research and the possible applications in forensics, particularly in sexual assault cases.

From Verogen, Inc. 16 Dec 2022

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

An experimental therapy showed promise as treatment for an aggressively spreading type of colorectal cancer in preclinical models, according to a new study by Weill Cornell Medicine investigators.

16 Dec 2022

New chemical compound shows promise to reverse effects of potentially deadly drugs

Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020-;more than five times the number of deaths in the year 2000-;and synthetic opioids like fentanyl are one of the main culprits.

16 Dec 2022

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Researchers described tree-based scan statistics for pediatric long COVID-19.

16 Dec 2022

Unexpected findings on the risk of SARS-CoV-2 infection

A new paper in Biology Methods & Protocols, published by Oxford University Press, investigates risk factors and protections against contracting COVID-19, and also for suffering from severe COVID.

15 Dec 2022

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Researchers evaluated the emergence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Canada.

15 Dec 2022

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, has published a report that was designed to assess clinical adoption, identify classification inconsistencies, and evaluate implementation barriers for the 2017 report, "Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.

15 Dec 2022

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Researchers from the Neurobiology of miRNA team coordinated by Davide De Pietri Tonelli at the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) has discovered the correlation between a class of small RNA molecules, piRNAs, and brain inflammation.

15 Dec 2022

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

After an intermittent fasting diet intervention, patients achieved complete diabetes remission, defined as an HbA1c (average blood sugar) level of less than 6.5% at least one year after stopping diabetes medication, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Dec 2022

Scientists uncover how FoxH1 factor binds to specific points in the genome

Transcription factors are proteins that interact with DNA to regulate the function of some genes. Generally, a single transcription factor binds to several regions in the genome as it orchestrates complex cellular responses, which require the activation or inhibition of several genes.

15 Dec 2022

Major treatment advance revealed for adults with newly diagnosed B lineage acute lymphoblastic leukemia

Late-breaking research reveals a major treatment advance for adults with newly diagnosed B lineage acute lymphoblastic leukemia (ALL).

14 Dec 2022

Scientists provide evidence of the positive effects of alcohol abstinence in advanced liver cirrhosis

Complete abstinence from alcohol is considered a cornerstone in the treatment of patients with alcohol-related liver disease. It has not yet been sufficiently researched whether this measure can still improve the prognosis even in the case of advanced liver cirrhosis.

14 Dec 2022

States challenge Biden to lower drug prices by allowing imports from Canada

The Biden administration is facing mounting pressure from states to let them import medicine from Canada to help lower prescription drug costs.

14 Dec 2022

Research maps the evolution and natural selection of E. coli bacteria

Antibiotic resistance, when infection-causing bacteria evolve so they are no longer affected by typical antibiotics, is a global concern.

14 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Medicaid expansion and increase in PrEP, antiretroviral treatment could result in decline of new HIV infections

Enacting Medicaid expansion in Texas and increasing the use of preventive and antiviral medications could result in a decline of new HIV infections among young Black gay, bisexual, and other men who have sex with men (MSM) in Houston, reports a study in the January issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.

13 Dec 2022

Virginia Tech researchers receive three grants to study the effects of ultra-processed foods

Scientists in the Virginia Tech College of Agriculture and Life Sciences are investigating the effects of ultra-processed foods on the human body using a variety of research tools.

13 Dec 2022

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Researchers develop new porous material capable of regenerating bones and preventing infections

Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.

12 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Laboratory News and Research

Next-generation sequencing could change research on sexual assault cases

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

New chemical compound shows promise to reverse effects of potentially deadly drugs

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Unexpected findings on the risk of SARS-CoV-2 infection

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

Study lays the groundwork for developing new technologies to detect neurodegenerative diseases

Intermittent fasting diet intervention may help patients to achieve complete diabetes remission

Scientists uncover how FoxH1 factor binds to specific points in the genome

Major treatment advance revealed for adults with newly diagnosed B lineage acute lymphoblastic leukemia

Scientists provide evidence of the positive effects of alcohol abstinence in advanced liver cirrhosis

States challenge Biden to lower drug prices by allowing imports from Canada

Research maps the evolution and natural selection of E. coli bacteria

Study uncovers a new immune culprit in Alzheimer’s disease

Medicaid expansion and increase in PrEP, antiretroviral treatment could result in decline of new HIV infections

Virginia Tech researchers receive three grants to study the effects of ultra-processed foods

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers develop new porous material capable of regenerating bones and preventing infections

How human cell atlases provide the missing links between genes, diseases and therapies

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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