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Scientists have discovered a genetic cause of cleft lip and palate in mice

By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.

29 Apr 2004

Time bomb in heart leads to heart failure in some congenital heart disease patients

However, surgical correction of certain forms of congenital heart disease may not fix the underlying molecular trigger that drives progressive heart failure and sudden death later in life, according to new research from the University of California, San Diego (UCSD) School of Medicine.

29 Apr 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

Scientists have unraveled the behavior of one key component of bacteria

The researchers studied a mechanism of action they call the "magic spot" – an important regulator of gene expression. They describe their results in the current issue of the journal Cell.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

In a paper that will be published on Thursday, April 29, 2004 in the New England Journal of Medicine, a team of scientists from Stanford University and Applied Biosystems, an Applera Corporation business, describe the identification of six genes associated with survival in diffuse large B cell lymphoma (DLBCL), the most common form of non-Hodgkin's lymphoma.

28 Apr 2004

The world's smallest computer made entirely of biological molecules

The world's smallest computer (around a trillion can fit in a drop of water) might one day go on record again as the tiniest medical kit.

28 Apr 2004

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

Saint Louis University researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness.

28 Apr 2004

AGT Biosciences Limited and ChemGenex Therapeutics today announced merger agreement

AGT Biosciences Limited of Melbourne, Australia and privately held ChemGenex Therapeutics, Inc. of Menlo Park, California, today announced that they have signed a merger agreement. The cross-border merger creates a new, genomics-driven pharmaceutical company with leading edge capabilities for drug discovery and development, as well as two drug candidates in Phase II human trials for cancer.

28 Apr 2004

$11 million for lung injury research

Northwestern University has received an $11 million Program Project Grant (PPG) from the National Institutes of Health to define the mechanisms that cause changes in the alveolar epithelium during lung injury.

27 Apr 2004

Experimental smallpox DNA vaccine

In the first successful study of its kind, scientists have shown that a DNA-based vaccine for smallpox can protect nonhuman primates from monkeypox, a disease that resembles smallpox in humans.

27 Apr 2004

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States and may have led to a doubling of its occurrence during the past 200 years, according to a study by hereditary deafness experts at Virginia Commonwealth University.

27 Apr 2004

Students to study compounds shown to prevent cancer drug resistance and studying tomato genes and proteins

Michigan State University’s new Goldwater Scholars for 2004 have a lot of work ahead of them – studying compounds shown to prevent cancer drug resistance and studying tomato genes and proteins.

26 Apr 2004

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Researchers at Duke University have developed a new analytical approach that combines genetic and clinical data to give cancer patients an individualized prognosis of their cancer recurrence. The information could prove critical in deciding how aggressively to treat the disease following surgery.

26 Apr 2004

Discovery shows how single genetic mutation can cause complex disorders

Bardet-Biedl syndrome (BBS), characterized by obesity, learning disabilities and eye and kidney problems, is caused by genetic mutations in the BBS family of genes. Now, researchers who've long studied the condition have discovered that genetic mutations in one of those genes, called BBS4, lead to cell death by disrupting the cells' internal "highway" system.

25 Apr 2004

Certain cells from a mother can cause immunity illness in children

Certain cells from a mother persist in their children’s bodies and can provoke an immune response in which the child’s body attacks itself, according to Mayo Clinic research published in the current issue of the Journal of Immunology (http://www.jimmunol.org).

23 Apr 2004

New techniques to search the yeast genome for genes that help keep copied chromosomes together

Johns Hopkins scientists have successfully used new techniques to search the yeast genome for genes that help keep copied chromosomes together, protecting the integrity of the organism's genetic material during cell division.

22 Apr 2004

Doctors from the University of Edinburgh and local intensive care units have linked to fight an antibiotic-resistant infection which attacks some hospital patients.

22 Apr 2004

Human cloning on a grand scale could spell the end of the species as we all become nastier

Human cloning on a grand scale could spell the end of the species as we all become nastier, warn researchers at the University of Sussex.

20 Apr 2004

Functional genomics provide improved drug discovery

Functional genomics and proteomics have been quite successful in identifying functions of potential therapeutic targets such as encoded proteins.

20 Apr 2004

Genes News and Research

Scientists have discovered a genetic cause of cleft lip and palate in mice

Time bomb in heart leads to heart failure in some congenital heart disease patients

New technique of identifying genes may help researchers developing drugs

Scientists have unraveled the behavior of one key component of bacteria

Lou Gehrig’s disease gene discovered

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

The world's smallest computer made entirely of biological molecules

Researchers have discovered the cause of one form of retinitis pigmentosa, a type of genetically inherited blindness

AGT Biosciences Limited and ChemGenex Therapeutics today announced merger agreement

$11 million for lung injury research

Experimental smallpox DNA vaccine

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

Students to study compounds shown to prevent cancer drug resistance and studying tomato genes and proteins

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Discovery shows how single genetic mutation can cause complex disorders

Certain cells from a mother can cause immunity illness in children

New techniques to search the yeast genome for genes that help keep copied chromosomes together

Doctors from the University of Edinburgh and local intensive care units have linked to fight an antibiotic-resistant infection which attacks some hospital patients.

Human cloning on a grand scale could spell the end of the species as we all become nastier

Functional genomics provide improved drug discovery

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