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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

Stanford Medicine launches a diagnostic test for monkeypox

Stanford Medicine's Clinical Virology Laboratory today launched a diagnostic test for the monkeypox virus that has been identified in 42 countries and several U.S. states, including California.

23 Jun 2022

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families.

23 Jun 2022

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Results of a study of molecular tumor profiling in young patients revealed a high rate of genetic alterations with potential for impacting clinical care, including clarifying diagnoses and treatment with matched, precision cancer drugs.

23 Jun 2022

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.

23 Jun 2022

New funding to help advance scientific understanding of skin disorders in children and young people

For children and young people, skin disorders can have a devastating impact on physical and mental wellbeing, yet effective treatments are few and far between.

23 Jun 2022

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers developed an integrated approach combining NGS, molecular barcoding, machine learning, and bioinformatics to enable high-throughput detection of SARS-CoV-2 variants.

23 Jun 2022

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Whole genome sequencing of 1,700-year-old individuals shows genetic heterogeneity in ancient Koreans from Gaya

An international team led by The University of Vienna and the Ulsan National Institute of Science and Technology in collaboration with the National Museum of Korea has successfully sequenced and studied the whole genome of eight 1,700-year-old individuals dated to the Three Kingdoms period of Korea (approx. 57 BC-668 AD).

21 Jun 2022

First open-source program can improve detection and tracking of pathogenic DNA sequences

It's a given that certain bacteria and viruses can cause illness and disease, but the real culprits are the sequences of concern that lie within the genomes of these microbes.

21 Jun 2022

Research may pave the way for a future test to diagnose ALS

Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons.

21 Jun 2022

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Researchers at Kyoto University have discovered the skin's natural protection from nighttime bacterial invasion in mice, which may provide a basis for eventually developing a drug treatment.

21 Jun 2022

Lack of biodiversity in the gut or elevated metabolites associated with heart failure severity

Some people who experience heart failure have less biodiversity in their gut or have elevated gut metabolites, both of which are associated with more hospital visits and greater risk of death, according to a systematic review of research findings led by Georgetown University School of Nursing & Health Study researchers and colleagues.

21 Jun 2022

DNA News and Research

Further Reading

New method helps unravel three-dimensional structure of the human genome

Stanford Medicine launches a diagnostic test for monkeypox

Inherited mutations in the MINAR2 gene lead to sensorineural deafness

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

New funding to help advance scientific understanding of skin disorders in children and young people

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Researchers map cancer driver mutations across the human genome

Whole genome sequencing of 1,700-year-old individuals shows genetic heterogeneity in ancient Koreans from Gaya

First open-source program can improve detection and tracking of pathogenic DNA sequences

Research may pave the way for a future test to diagnose ALS

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Lack of biodiversity in the gut or elevated metabolites associated with heart failure severity

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

Conceptual framework to examine the patterns of copy number alterations in human cancer

Ancient DNA unravels the mystery of the Black Death

International researchers win funding for Cancer Grand Challenge

International researchers will receive $25 million award to investigate the early stages of cancer development

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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