Immune System News and Research

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SARS-CoV-2 in diabetes pathogenesis

Researchers reviewed the causes of diabetes mellitus, focusing on respiratory viruses, including influenza virus and SARS-CoV-2.

15 Mar 2022

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna.

14 Mar 2022

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a Phase 1 clinical trial evaluating three experimental HIV vaccines based on a messenger RNA (mRNA) platform—a technology used in several approved COVID-19 vaccines.

14 Mar 2022

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms.

14 Mar 2022

Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters

A new study assessed the neutralization induced by subunit vaccine boosters specific for the SARS-CoV-2 Omicron variant of concern.

14 Mar 2022

New approach to send ‘friendly’ nano-particles into the body shows promising results

A new approach to send ‘friendly’ nano-particles into a patient’s blood stream has shown promising results by modifying the surface of these potential drug, vaccine or cancer treatment delivery objects to encourage the best result.

14 Mar 2022

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It's because they work better than the previous standard of care.

11 Mar 2022

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

Mice study shows how to improve long-term effectiveness of TB vaccine

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

11 Mar 2022

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

People who gained immunity -; either through vaccination or exposure -; against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant.

11 Mar 2022

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Cancer patients who have compromised immune systems due to their disease or therapy remain at high risk for COVID-19 infection.

10 Mar 2022

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19.

10 Mar 2022

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

LMU scientists have investigated how most people's immune defenses are able to curb the coronavirus so effectively that pneumonia does not occur.

10 Mar 2022

Association of benzodiazepines with SARS-CoV-2 positivity and clinical outcomes in three patient groups

A new study has evaluated the association of BZD use with the clinical outcomes of SARS-CoV-2 positive patients.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

Mechanical stress of confined migration makes cancer cells more aggressive

Squeezing through tight spaces makes cancer cells more aggressive and helps them evade cell death, shows a study published today in eLife.

9 Mar 2022

Study suggests recent common cold may actually lead to worse COVID-19 disease

A new study published in the Journal of Infectious Diseases shines an unexpected light on the notion that pre-existing immunity to common cold coronaviruses can protect us from coronavirus disease 2019 (COVID-19) – and reveals that this may actually put certain individuals at risk of more severe clinical presentations.

8 Mar 2022

Researchers secure $12 million grant to develop improved therapies for hemophilia

An Indiana University School of Medicine researcher will lead a multi-institute effort toward improved therapies for hemophilia with help from a $12 million grant from the National Heart Lung and Blood Institute.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Immune System News and Research

SARS-CoV-2 in diabetes pathogenesis

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Study explores neutralization of SARS-CoV-2 Omicron variant by subunit vaccine boosters

New approach to send ‘friendly’ nano-particles into the body shows promising results

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Mice study shows how to improve long-term effectiveness of TB vaccine

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

Association of benzodiazepines with SARS-CoV-2 positivity and clinical outcomes in three patient groups

The trajectory of B-cell immunity six months after mRNA vaccination

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

Mechanical stress of confined migration makes cancer cells more aggressive

Study suggests recent common cold may actually lead to worse COVID-19 disease

Researchers secure $12 million grant to develop improved therapies for hemophilia

Study reveals new insights on how immune system cells respond to disease-causing pathogens

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