Transplant News and Research

RSS

Light-chain amyloidosis patients treated with high-dose chemo and stem cell transplantation have long-term survival

Patients with Light-chain (AL) amyloidosis who are treated with high-dose chemotherapy (melphalan) and autologous (one's own) stem cell transplantation (HDM/SCT) have the greatest success for long-term survival.

9 Oct 2015

NIBIB-supported bioengineers work to reduce platelet activation and clotting in patients with VADs

A team of NIBIB-supported bioengineers, aerospace scientists, and cardiovascular clinicians are improving the function of the thousands of life-saving ventricular assist devices (VADs) implanted in advanced heart failure patients each year.

8 Oct 2015

Half-matched donor bone marrow transplant just as good as full match, new study shows

Bone marrow transplantation is a life-saving therapy for many patients with blood cancers like leukemias and lymphomas. Currently, the gold standard blood-generating stem cells are obtained from a donor, a sibling, with a perfect match to the patient in order to minimize the chance of rejection and other complications. However, not all patients will have a perfectly matched sibling. Some cancer centers have begun to explore whether half-matched donors might work just as well.

8 Oct 2015

Nurses who work with organ transplant patients experience high levels of emotional exhaustion

More than half of nurses who work with organ transplant patients in the United States experience high levels of emotional exhaustion, a primary sign of burnout, according to a study published by researchers at Henry Ford Hospital.

7 Oct 2015

Researchers explore how common genetic mutation influences effects of taking melatonin close to mealtime

Researchers from Brigham and Women's Hospital and the University of Murcia, Spain, have shed new light on why people who carry a common genetic mutation may be more at risk for developing type 2 diabetes. By carefully studying healthy subjects, researchers were able to chart the effect of melatonin supplements on blood sugar control.

7 Oct 2015

World Scientific publishes new book that covers all aspects of cancer care

Cervical, uterine and ovarian cancers are among the most common cancers affecting women, with a total of 1,087,000 new cases diagnosed worldwide in 2012.

1 Oct 2015

HLA-DPB1 regulatory region genotype predicts acute GVHD

Analysis of a HLA-DPB1 regulatory region variant has shed light on the risk of acute graft-versus-host disease in patients undergoing haematopoietic cell transplantation from an unrelated donor.

1 Oct 2015

University of Michigan-led team performs first kidney transplants in Ethiopia

A University of Michigan-led team performed the first kidney transplants in Ethiopia last week, after spending more than two years to help establish a transplant center in the African country.

30 Sep 2015

Matchmaker Exchange platform launched for uncovering rare disease genes

In a special issue of Human Mutation, a team including investigators at Brigham and Women's Hospital has announced the launch of the Matchmaker Exchange - a way for the rare disease community to share information and find new connections. Matchmaker Exchange connects databases of genetic information and symptoms that physicians and investigators can "match" with a patient's rare disease.

25 Sep 2015

Hyperbaric oxygen therapy improves outcomes of umbilical cord blood transplant patients

For the past 27 years, cord blood transplants have been a life-saving treatment option for thousands of people with leukemia, non-Hodgkins lymphoma, Hodgkins disease and myelodysplastic disorders. Cord blood helps replace cancerous blood cells and replenish a patient's own bone marrow and immune system. Even with its success, researchers are continually looking for ways to improve the transplant process and increase cure rates.

24 Sep 2015

Researchers extend innovative research towards a cure for type I diabetes

Associate Professor Shane Grey, of Sydney's Garvan Institute of Medical Research, together with collaborators from the Westmead Millennium Institute for Medical Research and the Children's Hospital at Westmead, have been awarded $3.3 million to extend their innovative research towards a cure for type I diabetes.

23 Sep 2015

Study demonstrates potential of FCPCs as new source for cartilage regeneration

The self-repair of injured cartilage is difficult for several reasons, foremost of which is the lack of blood supply to the tissue. Therapeutic efforts aimed at cartilage repair are often not optimal. Surgical repair techniques often lead to the formation of fibrocartilage, which is weaker and less durable. Although cell transplantation aimed at cartilage repair has been carried out using mesenchymal stem cells (MSCs), varying outcomes have resulted, despite the propensity of MSCs to proliferate and differentiate.

23 Sep 2015

UCSF researchers successfully separate human muscle stem cells

UC San Francisco researchers have successfully isolated human muscle stem cells and shown that the cells could robustly replicate and repair damaged muscles when grafted onto an injured site. The laboratory finding paves the way for potential treatments for patients with severe muscle injury, paralysis or genetic diseases such as muscular dystrophy.

23 Sep 2015

Donor and patient age more important in determining kidney transplant success

Infection by virus cytomegalovirus (CMV) is a common and major complication following kidney transplantation. Previous studies have related CMV infection with increased kidney transplant failure and reduced patient survival. However, a new study published in the American Journal of Physiology—Renal Physiology reports that the age of the donor and the recipient, not CMV infection, are more important factors in determining transplant success.

22 Sep 2015

New Medicare payment model reduces use of low-value services

In the first large-scale study to assess the effects of the Affordable Care Act's reforms to physician and hospital payments on the use of wasteful health care services, researchers have found that a new Medicare payment model reduced the number of times patients received services providing little or no health benefit.

22 Sep 2015

BWH, DFCI researchers receive $10 million to test effectiveness of aspirin in women with breast cancer

Researchers from Brigham and Women's Hospital and Dana-Farber Cancer Institute have received a $10 million Breakthrough Award from the Department of Defense's Office of the Congressionally Directed Medical Research Program to test whether aspirin helps women with breast cancer avoid recurrence and live longer.

22 Sep 2015

Researchers develop biophysical treatment method for dialysis patients

Researchers at Charité -- Universitätsmedizin Berlin have developed a biophysical treatment method that allows up to 50 percent more toxins to be removed from the blood of dialysis patients. Use of this technology may result in patients with kidney disease seeing a considerable reduction in the length of dialysis sessions. An initial patent application for this technology was filed in 2011.

21 Sep 2015

Transplant News and Research

Light-chain amyloidosis patients treated with high-dose chemo and stem cell transplantation have long-term survival

NIBIB-supported bioengineers work to reduce platelet activation and clotting in patients with VADs

Half-matched donor bone marrow transplant just as good as full match, new study shows

Nurses who work with organ transplant patients experience high levels of emotional exhaustion

Researchers explore how common genetic mutation influences effects of taking melatonin close to mealtime

World Scientific publishes new book that covers all aspects of cancer care

HLA-DPB1 regulatory region genotype predicts acute GVHD

University of Michigan-led team performs first kidney transplants in Ethiopia

Matchmaker Exchange platform launched for uncovering rare disease genes

Hyperbaric oxygen therapy improves outcomes of umbilical cord blood transplant patients

Researchers extend innovative research towards a cure for type I diabetes

Study demonstrates potential of FCPCs as new source for cartilage regeneration

UCSF researchers successfully separate human muscle stem cells

Donor and patient age more important in determining kidney transplant success

New Medicare payment model reduces use of low-value services

BWH, DFCI researchers receive $10 million to test effectiveness of aspirin in women with breast cancer

Researchers develop biophysical treatment method for dialysis patients

Hermansky-Pudlak syndrome can cause debilitating lung disease in Puerto Ricans

Winners of Renal Support Network's 13th Annual Essay Contest announced

Ninth annual Tour DaVita bike event to be held in NC to raise awareness on kidney disease

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News