Immune System News and Research

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Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

MUSC study sheds light on better ways to prevent and treat colorectal cancer

An MUSC Hollings Cancer Center study sheds light on better ways to prevent and treat colorectal cancer, which often is found at advanced stages when it's much harder to treat.

28 Feb 2022

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

A new data analysis tool developed by Yale researchers has revealed the specific immune cell types associated with increased risk of death from COVID-19, they report Feb. 28 in the journal Nature Biotechnology.

28 Feb 2022

Understanding the gut microbiome could help personalize immunotherapy for melanoma

The largest study to date has confirmed the link between the gut microbiome and the response to cancer immunotherapy therapy for melanoma.

28 Feb 2022

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

Gender-affirming hormone therapy could influence the way a person's genes are turned on or off, according to a new study.

28 Feb 2022

Study reveals new way viruses trigger autoimmunity

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems to attack their own bodies.

28 Feb 2022

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

A recent study evaluated the molecular and histopathological effects in the placenta following a SARS-CoV-2 infection during pregnancy.

28 Feb 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A new study discusses changes in the microbiota of various parts of the body with SARS-CoV-2 infection.

27 Feb 2022

Study reveals how the immune system can be triggered to fight cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

25 Feb 2022

Spectacular structure of C.difficile's protective armor revealed

The spectacular structure of the protective armor of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

25 Feb 2022

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

The stress of restaurant work is reaching a boiling point. Could a staff therapist help?

Restaurant jobs have always been difficult, but the mental stress has gotten worse during the pandemic as restaurants closed or cut hours — or became ground zero for the fight over mask-wearing.

25 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Scientists reveal the possibility to improve immunological memory in vaccines

A key transcription factor in T-cell immunology is crucial to the immune system's "memory" in recognizing threats it has already faced before – and it may be possible to improve this immunological memory in vaccines, according to a new paper by scientists at the Hackensack Meridian Center for Discovery and Innovation.

24 Feb 2022

Study finds two doses of COVID-19 vaccines were insufficient to neutralize the SARS-CoV-2 Omicron variant

Researchers determined the neutralization potency of sera from people vaccinated with BNT162b2, mRNA-1273, or ChAdOx1 against the novel SARS-CoV-2 Omicron variant.

24 Feb 2022

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

Researchers investigated whether residual SARS-CoV-2 antigens and RNA are present in tissues samples of long COVID-19 patients beyond the convalescent phase of COVID-19.

24 Feb 2022

Immune System News and Research

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

MUSC study sheds light on better ways to prevent and treat colorectal cancer

New data analysis tool reveals immune cell types associated with COVID-19 mortality risk

Understanding the gut microbiome could help personalize immunotherapy for melanoma

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

Study reveals new way viruses trigger autoimmunity

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

Study reveals how the immune system can be triggered to fight cancer cells

Spectacular structure of C.difficile's protective armor revealed

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Research could pave the way for adoption of precision medicine approaches for COVID-19

The stress of restaurant work is reaching a boiling point. Could a staff therapist help?

Mapping cells to understand vascular disease

Scientists reveal the possibility to improve immunological memory in vaccines

Study finds two doses of COVID-19 vaccines were insufficient to neutralize the SARS-CoV-2 Omicron variant

Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID

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