Transplant News and Research

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Ex-vivo lung perfusion technique can reduce risk of transplant rejection

University of Manchester researchers have used a new technique to recondition poorly functioning lungs and remove donor white blood cells in an attempt to increase the number of lungs available for transplant, and at the same time reduce the risk of acute rejection.

15 Sep 2015

Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

Sun Biomedical Limited today announced the first patient had been enrolled in a Phase II study of DMX-200, an innovative new treatment that combines two different drugs to treat chronic kidney disease.

15 Sep 2015

Researchers show how a cell surface protein can mobilize immune cells to attack malignant tumors

Revealing a biological combat strategy worthy of a five-star general, researchers from Houston Methodist Hospital, University of Chicago and Cornell University have shown how a cell surface receptor--a specialized protein which communicates signals between a cell and the outside world--can mobilize immune cells to attack, rather than protect, malignant tumors.

15 Sep 2015

Future of transplant medicine to be explored during LifeNet Health Institute of Regenerative Medicine symposium

The LifeNet Health Institute of Regenerative Medicine is bringing together scientists and surgeons from around the world to explore the future of transplant medicine during its Scientific Symposium Sept. 25-26.

14 Sep 2015

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

One week ago, surgical teams took part in a record-setting day of organ transplantation at Baylor University Medical Center at Dallas. Surgeons on the medical staff performed nine organ transplants on seven patients in one calendar day.

11 Sep 2015

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Targeting exhausted immune cells may change the prognosis for patients with acute myeloid leukemia (AML) relapse after a stem cell transplant, according to Penn State College of Medicine researchers.

11 Sep 2015

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

New research will help scientists and medical professionals to better understand the long-term complications caused by an immunosuppressant drug used to treat thousands of kidney transplant patients.

11 Sep 2015

BWH partners with MCHS to develop unique fetal program

Experts from BWH will partner with MCHS to provide recommendations related to the development of the program, including establishing a high-risk-fetal labor and delivery unit at Nicklaus Children's Hospital, slated to open in 2017, as well as guidance on clinical protocols and opportunities for training and education.

10 Sep 2015

Liver failure patients may benefit from CSF-1 treatment that aids the immune system to combat infections

Patients with liver failure could benefit from a treatment that helps the immune system to combat infections linked to the condition, research suggests.

10 Sep 2015

Simple stem cell production method shows promise in mice for treating IPF

In a small pilot study, researchers from North Carolina State University have demonstrated a rapid, simple way to generate large numbers of lung stem cells for use in disease treatment. This method of harvesting and growing a patient's own lung stem cells shows promise in mice for treating idiopathic pulmonary fibrosis (IPF), and could one day provide human IPF sufferers with an effective, less invasive method of treatment for their disease.

10 Sep 2015

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

Alzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death among the elderly and the leading cause of dementia. Predictions are that the number of AD cases will quadruple by 2050.

9 Sep 2015

Simple test can lead to early detection of sleep apnea in hospitalized heart failure patients

Researchers at Thomas Jefferson University showed that a simple questionnaire, evaluation and pulse-oximetry monitoring can lead to early detection of sleep apnea in patients hospitalized for congestive heart failure (CHF).

9 Sep 2015

New study of DCD liver transplantations finds no significant link between donor age and organ survival

Organ donation after circulatory death (DCD), in which transplant organs are taken from donors after ay period of no blood circulation or oxygenation, is often considered inferior to donation after brain death, in which circulation and oxygenation are maintained until organs are removed for transplantation. Currently, the use of livers from DCD donors remains controversial, particularly with donors with advanced age.

9 Sep 2015

Common drug used for treating fungal infections in lung transplant recipients increases risk for skin cancer, death

Voriconazole, a prescription drug commonly used to treat fungal infections in lung transplant recipients, significantly increases the risk for skin cancer and even death, according to a new study by UC San Francisco researchers.

3 Sep 2015

Researchers develop new method that can target drug delivery to the lung

Researchers from Columbia Engineering and Columbia University Medical Center have developed a new method that can target delivery of very small volumes of drugs into the lung.

3 Sep 2015

University of Maryland Medicine offers MRI-guided focused ultrasound treatment to Parkinson's patients

University of Maryland Medicine (the University of Maryland Medical Center and the University of Maryland School of Medicine) and its Center for Metabolic Imaging and Image-Guided Therapeutics (CMIT) has begun to use MRI-guided focused ultrasound on a deep structure within the brain related to Parkinson's disease - the globus pallidus.

2 Sep 2015

Mouse study shows active ingredient in marijuana may delay rejection of incompatible organs

Here's another discovery to bolster the case for medical marijuana: New research in mice suggests that THC, the active ingredient in marijuana, may delay the rejection of incompatible organs.

2 Sep 2015

$Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction$

Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction

Gene transfer therapy aimed at correcting an enzyme abnormality involved in myocardial contraction and relaxation did not improve outcomes in heart failure patients with reduced ejection fraction, results of the CUPID 2 study show.

1 Sep 2015

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarker, physicians for the first time have a tool to decide which treatment option is best for patients with Klatskin carcinoma, one type of bile duct cancer.

1 Sep 2015

Findings reveal a new way to prevent meningitis

The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year — mainly those with impaired immune systems due to AIDS, cancer treatment or an organ transplant.

28 Aug 2015

Transplant News and Research

Ex-vivo lung perfusion technique can reduce risk of transplant rejection

Sun Biomedical begins DMX-200 Phase II trial for treatment of chronic kidney disease

Researchers show how a cell surface protein can mobilize immune cells to attack malignant tumors

Future of transplant medicine to be explored during LifeNet Health Institute of Regenerative Medicine symposium

Surgeons participate in record-setting day of organ transplantation at Baylor University Medical Center

Targeting exhausted immune cells may change prognosis for leukemia relapse patients after transplant

Study may help scientists to better understand complications caused by drug therapy in kidney transplant patients

BWH partners with MCHS to develop unique fetal program

Liver failure patients may benefit from CSF-1 treatment that aids the immune system to combat infections

Simple stem cell production method shows promise in mice for treating IPF

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

Simple test can lead to early detection of sleep apnea in hospitalized heart failure patients

New study of DCD liver transplantations finds no significant link between donor age and organ survival

Common drug used for treating fungal infections in lung transplant recipients increases risk for skin cancer, death

Researchers develop new method that can target drug delivery to the lung

University of Maryland Medicine offers MRI-guided focused ultrasound treatment to Parkinson's patients

Mouse study shows active ingredient in marijuana may delay rejection of incompatible organs

Gene transfer therapy not beneficial for heart failure patients with reduced ejection fraction

MACC1 gene can help predict better treatment options for patients with Klatskin carcinoma

Findings reveal a new way to prevent meningitis

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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