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Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results of the Phase II SUMMIT trial reported by researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

New report provides latest update on cardiovascular disease burden and trends

A world without cardiovascular disease (CVD) is possible, yet millions of lives are lost prematurely to heart disease each year, according to the new Global Burden of Disease (GBD) special report published today in the Journal of the American College of Cardiology.

11 Dec 2023

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

The associations between meat and fish consumption and the risk of non-alcoholic fatty liver disease (NAFLD).

11 Dec 2023

The influence of vitamin supplementation on longitudinal patterns of maternal vitamin status from preconception to post-delivery

Researchers secondary analyzed the NiPPeR randomized clinical trial (RCT) data to assess maternal vitamin levels pre-conception, during pregnancy, and post-delivery and also explored the impact of vitamin supplementation before and during gestation.

11 Dec 2023

From surviving to thriving: a framework for long-term success in people with HIV

NewsMedical spoke to Lisa Sterman, Global Executive Director, Global HIV Medical Affairs, Gilead Sciences, about the recently published LTS framework, recently highlighted at the opening ceremony of the 19th European AIDS Conference, which takes a person-centric approach to the HIV treatment journey.

From Gilead Sciences, Inc. 11 Dec 2023

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

A research team led by Hong Kong Baptist University (HKBU) has developed a novel drug delivery system for Alzheimer’s disease (AD).

11 Dec 2023

‘Naughty but nice’ Christmas foods can help achieve a better balance of cholesterol, expert says

Finally, there’s good news about many of our favorite Christmas foods. A turkey meal with all – well, most – of the trimmings and a traditional dessert can lower your LDL ‘bad’ cholesterol levels and improve your ratio of HDL good cholesterol, reveals a leading testing expert.

11 Dec 2023

COVID-19 significantly raises risk of severe complications in pregnant women

Study found that pregnant mothers with COVID-19 face a significantly higher risk of severe maternal morbidity (SMM), including adult respiratory distress syndrome and acute renal failure, emphasizing the urgent need for their early diagnosis and treatment.

10 Dec 2023

Study shows low-fat milk may increase prediabetes risk, high-fat yogurt lowers it

Study in The American Journal of Clinical Nutrition found an association between dairy intake and prediabetes risk, highlighting that low-fat milk consumption may increase prediabetes risk, while high-fat yogurt is linked to a reduced risk, particularly among highly educated individuals.

10 Dec 2023

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Using machine learning, researchers successfully distinguished factors of healthy aging from chronic disease risks by analyzing health data across various ages, finding key markers like neutrophil counts and alkaline phosphatase levels as early indicators of healthy aging.

10 Dec 2023

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Study shows that Guayusa extract and Nordic Lion’s Mane (LM) improve subjective cognitive perception and objective cognitive performance, highlighting their potential benefits in enhancing cognitive functions and mood.

10 Dec 2023

Global study reveals hypertension common among middle-aged couples

Study reports high prevalence of concordant hypertension among middle-aged heterosexual couples in England, the US, India, and China, suggesting couple-centered interventions could be effective in hypertension management.

10 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Study links organic Mediterranean diet to improved male fertility

Researchers in Italy have found that a low-carbohydrate organic Mediterranean diet significantly enhances male fertility by increasing testosterone levels and reducing sperm DNA fragmentation, offering new dietary guidelines for improving male reproductive health.

10 Dec 2023

Using near-infrared spectroscopy to study how infant brains respond to touch

Researchers from Tokyo Metropolitan University have measured how oxygenated hemoglobin levels in the blood change in infants' brains in response to touch.

9 Dec 2023

New insights into how anti-obesity drugs could help prevent kidney disease

Data from Australian researchers could partly explain why a trial of a new drug for diabetes, was recently halted because it was found to be so effective.

8 Dec 2023

Scientists unveil 3D structure of key immune system component

An international team of researchers from LMU and the Helmholtz Centre for Infection Research has visualized the structure of the so-called ASC speck.

8 Dec 2023

Exploring the role of liquid biopsies in early-stage prostate cancer

A new research perspective was published in Oncoscience (Volume 10) on November 30, 2023, entitled, "Evolving insights in blood-based liquid biopsies for prostate cancer interrogation."

8 Dec 2023

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Mathieu Vinken, a professor in the In Vitro Toxicology and Dermato-cosmetology (IVTD) lab at the Vrije Universiteit Brussel, and doctoral student Raf Van Campenhout have developed a technique based on nanobody technology to prevent liver inflammation.

8 Dec 2023

Blood News and Research

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

New report provides latest update on cardiovascular disease burden and trends

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

The influence of vitamin supplementation on longitudinal patterns of maternal vitamin status from preconception to post-delivery

From surviving to thriving: a framework for long-term success in people with HIV

Researchers develop novel exosome-based drug delivery system to treat Alzheimer's disease

‘Naughty but nice’ Christmas foods can help achieve a better balance of cholesterol, expert says

COVID-19 significantly raises risk of severe complications in pregnant women

Study shows low-fat milk may increase prediabetes risk, high-fat yogurt lowers it

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Natural supplements Guayusa tea and Lion’s Mane boost cognitive performance, study finds

Global study reveals hypertension common among middle-aged couples

Study explores the intricate gut-brain-liver connection and its impact on health

Study links organic Mediterranean diet to improved male fertility

Using near-infrared spectroscopy to study how infant brains respond to touch

New insights into how anti-obesity drugs could help prevent kidney disease

Scientists unveil 3D structure of key immune system component

Exploring the role of liquid biopsies in early-stage prostate cancer

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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