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IBN develops biochip for investigating the effect of drugs on cancer stem cells

Researchers at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, have developed a miniaturized biochip for investigating the effect of drugs on cancer stem cells (CSCs). Published recently in Nano Today, this new technology could boost the development of more effective cancer drugs.

9 May 2012

Salix first quarter total product revenue increases 62% to $171.1M

Salix Pharmaceuticals, Ltd. today announced financial and operating results for the first quarter ended March 31, 2012 and other business updates.

8 May 2012

New research about why people forego colorectal cancer screening

New research about why people forego colorectal cancer (CRC) screening suggests that three fears play a significant role; fear of embarrassment, fear of getting AIDS and fear of pain may make some seniors skip the potentially lifesaving tests.

5 May 2012

Improved lung-cancer screening by combining blood test with CT imaging

National Jewish Health is seeking to refine and improve lung-cancer screening by combining a blood test with CT imaging to detect disease earlier and more effectively. The trial combines a CT chest scan and the EarlyCDT-Lung blood test to screen for cancer, and seeks to build on recent research demonstrating that CT screening alone can reduce lung-cancer mortality.

4 May 2012

Presence of fetal cells is a double-edged sword for women

For the first time, scientists have found what could be a causative link between the concentration of circulating Y-chromosome fetal cells in women who gave birth to children of either sex and their risk of later developing breast cancer and colon cancer.

4 May 2012

Hispanics more likely to develop precancerous colorectal polyps

Blacks and Hispanics have a significantly higher risk of developing precancerous colorectal polyps compared with whites, according to a study by researchers at NewYork - Presbyterian Hospital/Columbia University Medical Center.

4 May 2012

GOS prompts body's natural killer cells to ward off colon cancer

Researchers at Michigan State University have shown a prebiotic may help the body's own natural killer cells fight bacterial infection and reduce inflammation, greatly decreasing the risk of colon cancer.

4 May 2012

Researchers identify switches that can turn on or off genes associated with colorectal cancer

Two researchers at the Geisel School of Medicine at Dartmouth have helped to identify switches that can turn on or off genes associated with colorectal cancer. The finding offers clues about the development of colorectal cancer and could-potentially-provide targets for new therapies.

4 May 2012

Expression of tyrosine kinases may limit effectiveness of agents against sarcomas

To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or "off" switches important in the biology of cancer. The tyrosine kinases they identified, the researchers said, could act as "drivers" for the growth and survival of sarcomas.

2 May 2012

Synthetic stool transplant for C. difficile treatment

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C. difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.

2 May 2012

Tyrosine kinases could act as drivers for growth and survival of sarcomas

2 May 2012

Research roundup: Practice guidelines may not stop defensive medicine; English language ability tied to hospital readmission rates

The Value of Clinical Practice Guidelines As Malpractice "Safe Harbors" -- Overspending on health care has frequently been attributed to doctors practicing defensive medicine -- ordering extra tests, for example -- so that they avoid malpractice lawsuits. The authors of this brief write that while some have said clinical guidelines "should give caregivers a liability 'safe harbor,' shielding them from any malpractice claim for failing to provide services not included in the guideline."

27 Apr 2012

Consumption of resistant starch leads to positive changes in the bowel

Consumption of resistant starch leads to positive changes in the bowel and could protect against genetic damage implicated in bowel cancer.

27 Apr 2012

Gamma and delta-tocopherols do prevent many cancers

Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil. While the question of whether vitamin E prevents or promotes cancer has been widely debated in scientific journals and in the news media, scientists at the Center for Cancer Prevention Research, at Rutgers Mario School of Pharmacy, and the Cancer Institute of New Jersey, believe that two forms of vitamin E - gamma and delta-tocopherols - found in soybean, canola and corn oils as well as nuts do prevent colon, lung, breast and prostate cancers.

27 Apr 2012

Diseases of the Colon & Rectum app now available for the iPad

Essential research and the latest commentary from the field of colorectal surgery is now available in a digital format with the availability of Diseases of the Colon & Rectum (DC&R) app for the iPad edition.

27 Apr 2012

Aspirin reduces bowel cancer death and lung cancer incidence: Research suggests

There is previous evidence suggesting aspirin might prevent certain cancers from developing in the first place. And more recent work suggests it might also work as a cancer therapy - slowing down or preventing a cancer's spread. But the drug can also have unpleasant and dangerous side effects, causing irritation of the stomach lining and internal bleeds in a very small minority of patients.

26 Apr 2012

Eating pistachios may help alter levels of beneficial bacteria in the gut

A preliminary 16-person study suggests that eating pistachios may help alter levels of potentially beneficial bacteria in the gut, a finding that holds promise for supporting digestive health. The research, presented as an abstract this week at the Experimental Biology conference, is the first study of pistachios and almonds and their modulating role on the gut microbiota composition.

25 Apr 2012

Study: hUC-MSCs reduce inflammation that causes colitis

When laboratory mice were modeled with colitis and treated with human umbilical cord-derived mesenchymal cells, the cells homed in on the inflamed colon and effectively ameliorated colitis, reported a study published in a recent issue of Cell Transplantation.

24 Apr 2012

Vitamin E form of gamma-tocopherols beneficial in preventing cancers

Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil.

23 Apr 2012

Possibility to render cancer tumours harmless without affecting other cells

New research findings show how it may be possible to render cancer tumours harmless without affecting the other cells and tissues in the body. The findings apply to cancers including breast, lung and bowel cancer. The study was carried out at Lund University in Sweden.

20 Apr 2012