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Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Second-line treatment for drug-resistant tuberculosis is as effective as first-line medicines

Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO Centers in Haiti.

27 Feb 2024

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago, a new study reveals.

27 Feb 2024

Smartphone app uses AI and facial-image processing software to reliably detect the onset of depression

Dartmouth researchers report they have developed the first smartphone application that uses artificial intelligence paired with facial-image processing software to reliably detect the onset of depression before the user even knows something is wrong.

27 Feb 2024

Proximity to unhealthy food environments raises heart failure risk

Living close to pubs, bars and fast-food restaurats may lead to a higher risk of heart failure, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

27 Feb 2024

Without Medicare Part B’s shield, patient’s family owes $81,000 for a single air-ambulance flight

Debra Prichard was a retired factory worker who was careful with her money, including what she spent on medical care, said her daughter, Alicia Wieberg. "She was the kind of person who didn't go to the doctor for anything."

27 Feb 2024

UK lags in cancer treatment compared to other countries

People in the UK were treated with chemotherapy and radiotherapy less often than in comparable countries and faced long waits for treatments, according to two new studies published in The Lancet Oncology.

26 Feb 2024

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that UMSOM faculty scientists have been selected as key contractors by the Biomedical Advanced Research and Development Authority (BARDA), for the federal agency's Radiation Nuclear Animal Model Development program.

26 Feb 2024

Research unveils major discovery in gut-brain axis communication

The mechanisms by which antidepressants and other emotion-focused medications work could be reconsidered due to an important new breakthrough in the understanding of how the gut communicates with the brain.

26 Feb 2024

Cognitive behavioral therapy helps prevent postpartum mental health challenges in low-resource settings

Results from a large clinical trial funded by the National Institutes of Health show that an intervention for anxiety provided to pregnant women living in Pakistan significantly reduced the likelihood of the women developing moderate-to-severe anxiety, depression, or both six weeks after birth.

26 Feb 2024

Omalizumab boosts tolerance to multiple food allergies, study finds

A study in The New England Journal of Medicine shows omalizumab increases allergen tolerance in individuals with multiple food allergies, offering a promising standalone treatment option.

26 Feb 2024

Vaping increases susceptibility to COVID-19 infection, study finds

Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a University of California, Riverside, study has found.

26 Feb 2024

Wayne State researchers lead $9.6 million study on cancer genetics in African Americans

A team of researchers from Wayne State University and the Barbara Ann Karmanos Cancer Institute has received a five-year, $9.6 million grant from the National Cancer Institute of the National Institutes of Health for the study "Genetic Variation in Cancer Risk and Outcomes in African Americans."

26 Feb 2024

Neuropsychiatric symptoms can be potential predictors of Alzheimer's development

As the years add up, it's common to notice slight changes in our ability to remember and think. Older people who have more marked changes than their peers can be diagnosed with mild cognitive impairment (MCI).

26 Feb 2024

Study links extreme heat exposure in third trimester to increased preterm birth risk

In the face of increasing temperatures globally, a new Monash-led study of 1.2 million births in Sydney over two decades has shown a strong association between the risk of pre-term birth and exposure to extreme hot temperatures in the third trimester of pregnancy.

26 Feb 2024

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced "beta") in the pancreas, leading to a lack of insulin and inability to regulate blood sugar.

26 Feb 2024

Medicine News and Research

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Second-line treatment for drug-resistant tuberculosis is as effective as first-line medicines

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

Smartphone app uses AI and facial-image processing software to reliably detect the onset of depression

Proximity to unhealthy food environments raises heart failure risk

Without Medicare Part B’s shield, patient’s family owes $81,000 for a single air-ambulance flight

UK lags in cancer treatment compared to other countries

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

Research unveils major discovery in gut-brain axis communication

Cognitive behavioral therapy helps prevent postpartum mental health challenges in low-resource settings

Omalizumab boosts tolerance to multiple food allergies, study finds

Vaping increases susceptibility to COVID-19 infection, study finds

Wayne State researchers lead $9.6 million study on cancer genetics in African Americans

Neuropsychiatric symptoms can be potential predictors of Alzheimer's development

Study links extreme heat exposure in third trimester to increased preterm birth risk

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

Study reveals BCG vaccine's unexpected role in fighting influenza

AGA Research Foundation secures $1.4 million endowment grant for pancreatic cancer research

Harnessing multi-omics and AI for atherosclerotic cardiovascular disease management

Healthcare leaders advocate for restoring Canada's hypertension control program

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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