Angina News and Research

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Angina is chest pain or discomfort that occurs when an area of your heart muscle doesn't get enough oxygen-rich blood. Angina may feel like pressure or squeezing in your chest. The pain also may occur in your shoulders, arms, neck, jaw, or back. It can feel like indigestion.

Benefits of cardioprotective drugs may extend beyond preventing acute coronary syndromes

Medications prescribed to prevent heart attacks such as statins and aspirin are also associated with reduced heart attack severity, according to research published in PLOS ONE.

19 Sep 2016

Research suggests living in racially hostile environment can shorten lives of blacks and whites

Living in unabashedly racist communities can shorten the lives of both blacks and whites, according to new research from the University of California, Berkeley.

7 Sep 2016

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

New generation drug eluting stents (new DES) did not outshine contemporary bare metal stents (BMS) as they were expected to, in a surprise finding of the largest randomized stent trial to date.

30 Aug 2016

BBK II trial compares two commonly used stenting techniques for coronary bifurcation

Coronary bifurcations - a type of coronary artery narrowing - are best treated with a technique known as culotte stenting, as opposed to T-and-protrusion (TAP) stenting, when there is need for a side-branch stent according to results of the BBK II (Bifurcations Bad Krozingen) trial.

30 Aug 2016

$Lipoprotein apheresis may have new role in patients with refractory angina$

Lipoprotein apheresis may have new role in patients with refractory angina

Initial investigation of patients with suspected coronary heart disease (CHD) using functional imaging - rather than guideline-directed care - resulted in significantly less unnecessary angiography, according to results of the CE-MARC 2 trial.

29 Aug 2016

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Survival and other cardiovascular outcomes were not significantly reduced with intensive treatment using a second-line cholesterol-lowering medication on top of a standard statin, compared to statin treatment alone in patients with acute coronary syndrome (ACS) and dyslipidemia, investigators reported here.

29 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

New study to examine genomics of anti-platelet therapy after coronary interventions

Which antiplatelet medication is best after a coronary stent? The Tailored Antiplatelet Therapy to Lessen Outcomes After Percutaneous Coronary Intervention (TAILOR-PCI) Study examines whether prescribing heart medication based on a patient's CYP2C19 genotype will help prevent heart attack, stroke, unstable angina, and cardiovascular death in patients who undergo percutaneous coronary intervention (PCI), commonly called angioplasty.

29 Jul 2016

Diabetic patients experience long-term survival outcomes with TAR/CABG surgery

Diabetic patients who undergo heart bypass surgery are living longer and have much better long-term outcomes when cardiothoracic surgeons use arteries rather than veins for the bypasses, according to a new study published online today by The Annals of Thoracic Surgery.

14 Jul 2016

Metabolic syndrome, cardiovascular events linked to decreased sexual activity in postmenopausal women

Understanding the effects of age and disease on sexual wellbeing is crucial as sexual health is increasingly associated with vitality. In a new study published in The American Journal of Medicine, researchers looked at the role metabolic syndrome and cardiovascular disease play in postmenopausal women's sexual health.

13 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

miRNAs may improve risk prediction in CAD

Single microRNAs derived from peripheral blood predict cardiovascular mortality in patients with coronary artery disease, German research shows.

6 Jul 2016

Ticagrelor drug shows minor added benefit for patients with history of myocardial infarction

The German Institute for Quality and Efficiency in Health Care assessed the added benefit of ticagrelor for patients with acute coronary syndrome already in 2011 in its very first dossier assessment, just after the Act on the Reform of the Market for Medicinal Products had come into force.

5 Jul 2016

FDA approves Absorb GT1 BVS to treat coronary artery disease

The U.S. Food and Drug Administration today approved the first fully absorbable stent to treat coronary artery disease.

5 Jul 2016

Post-MI angina linked to increased late readmission risk

US researchers are calling for greater surveillance and treatment of post-myocardial infarction angina after their findings show an increased risk of late readmission among patients with angina symptoms at 30 days.

18 Jun 2016

Study links whole grain consumption to positive health effects

Eating three more portions of dietary fiber a day--say, two pieces of whole grain bread and a bowl of whole grain breakfast cereal--is associated with a lower risk for all cardiovascular diseases and for dying of cancer, diabetes, and respiratory and infectious diseases, a study just published in the BMJ has shown.

16 Jun 2016

CHD rates decrease significantly in the U.S.

Significant improvements seen across multiple sociodemographic groups, according to a new study in the American Journal of Preventive Medicine

15 Jun 2016

Female migraine patients have increased cardiovascular disease risk

Women who suffer from migraine headaches have a slightly increased risk of developing cardiovascular disease in later life. A team of researchers led by Prof. Tobias Kurth, Head of the Institute of Public Health at Charité - Universitätsmedizin Berlin, has now been able to establish the following: female migraine patients have a higher risk of stroke or heart attacks than women without migraine.

15 Jun 2016

Mortality risk high among diabetes patients with prior CV events

Patients with Type 2 diabetes and acute coronary syndromes have a substantially increased risk of death in the 18 months after hospital admission for subsequent major nonfatal cardiovascular events, US researchers report.

15 Jun 2016

Diabetes-heart disease combination can increase death risk

The combination of type 2 diabetes and coronary artery disease can be deadly. New research from a global study led by a physician from UConn Health has found that patients with Type 2 diabetes admitted into the hospital for congestive heart failure face a one in four chance of dying over the next 18 months.

13 Jun 2016

Angina News and Research

Further Reading

Benefits of cardioprotective drugs may extend beyond preventing acute coronary syndromes

Research suggests living in racially hostile environment can shorten lives of blacks and whites

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

BBK II trial compares two commonly used stenting techniques for coronary bifurcation

Lipoprotein apheresis may have new role in patients with refractory angina

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

New study to examine genomics of anti-platelet therapy after coronary interventions

Diabetic patients experience long-term survival outcomes with TAR/CABG surgery

Metabolic syndrome, cardiovascular events linked to decreased sexual activity in postmenopausal women

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

miRNAs may improve risk prediction in CAD

Ticagrelor drug shows minor added benefit for patients with history of myocardial infarction

FDA approves Absorb GT1 BVS to treat coronary artery disease

Post-MI angina linked to increased late readmission risk

Study links whole grain consumption to positive health effects

CHD rates decrease significantly in the U.S.

Female migraine patients have increased cardiovascular disease risk

Mortality risk high among diabetes patients with prior CV events

Diabetes-heart disease combination can increase death risk

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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