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Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

30 May 2024

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).

30 May 2024

Three-year study shows lingering effects of COVID-19

New findings on long COVID -; long-term effects on health experienced by many who have had COVID-19 -; present a good-news, bad-news situation, according to a study at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

30 May 2024

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

A team of researchers from the Institute of Oncology of the University of Oviedo (IUOPA), the Josep Carreras leukemia Research Institute, the University of Barcelona and the Centre for Biomedical Research in Cancer Network (CIBERONC) have demonstrated that some childhood leukemia originate during embryonic development, although they do not manifest after a few months after birth.

30 May 2024

Understanding the long-term effects and safety of testosterone therapy in transgender men

Transgender individuals often face unique challenges in aligning their physical bodies with their true gender identity.

30 May 2024

How tight binding between immune cells dictates T cell cancer-fighting ability

Immunotherapy, treatments that reinvigorate immune cells' anti-cancer activity or reprogram T cells to target cancer, has shown promise in treating leukemias but has not yet been realized in solid tumors.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Female and male heart failure may require distinct treatments

A new study from the UC Davis School of Medicine found striking differences at the cellular level between male and female mice with heart failure with preserved ejection fraction (HFpEF).

30 May 2024

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

One of Montana's largest health clinics that serves people in poverty has cut back services and laid off workers.

30 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Delayed multiple sclerosis diagnosis underscores need for urgent research and awareness boost, report find

A new report from MS Australia reveals that the average time to diagnose multiple sclerosis is nearly four years, highlighting the urgent need for increased research investment and enhanced awareness.

29 May 2024

Heart-healthy habits keep you biologically young, study shows

A new study in the Journal of the American Heart Association reveals that heart-healthy lifestyle factors are linked to younger biological age and lower cardiovascular disease risk through DNA methylation.

29 May 2024

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

A recent study in the Journal of Clinical Medicine found that oral semaglutide significantly improves glycemic control and reduces body weight in type 2 diabetes patients after 24 weeks of treatment.

29 May 2024

Study examines the effects of pregnant mother's epilepsy medications on child's creativity

While older drugs for epilepsy, taken while pregnant, have been shown in previous research to affect the creative thinking of children, a new study finds no effects on creativity for children born to those taking newer epilepsy drugs.

29 May 2024

Transparent skull implant unveils new frontiers in brain imaging

In the first study of its kind, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) designed and implanted a transparent window in the skull of a patient, then used functional ultrasound imaging (fUSI) to collect high-resolution brain imaging data through the window.

29 May 2024

Novel method predicts cancer cell behaviors using nano informatics and machine learning

A recent study has introduced a novel method combining nano informatics and machine learning to precisely predict cancer cell behaviors, enabling the identification of cell subpopulations with distinct characteristics like drug sensitivity and metastatic potential.

29 May 2024

New type of immunotherapy shows promising preclinical results against osteosarcoma

A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.

29 May 2024

Timely transition from pediatric to adult care reduces hospitalizations for sickle cell patients

Individuals living with sickle cell disease (SCD) who experience a delay of more than six months in transitioning from pediatric to adult care are twice as likely to be hospitalized compared to those who transition in less than two months, according to a study published in Blood Advances.

29 May 2024

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Blood News and Research

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Three-year study shows lingering effects of COVID-19

Genomic evidence of prenatal origins in childhood acute myeloid leukemia

Understanding the long-term effects and safety of testosterone therapy in transgender men

How tight binding between immune cells dictates T cell cancer-fighting ability

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Newly discovered lincRNA controls the development and function of regulatory T cells

Existing drug alleviates symptoms of a rare genetic syndrome

Female and male heart failure may require distinct treatments

Safety-net health clinics cut services and staff amid Medicaid ‘unwinding’

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Delayed multiple sclerosis diagnosis underscores need for urgent research and awareness boost, report find

Heart-healthy habits keep you biologically young, study shows

Oral semaglutide shows significant promise in improving diabetes control and cardiovascular health, study reveals

Study examines the effects of pregnant mother's epilepsy medications on child's creativity

Transparent skull implant unveils new frontiers in brain imaging

Novel method predicts cancer cell behaviors using nano informatics and machine learning

New type of immunotherapy shows promising preclinical results against osteosarcoma

Timely transition from pediatric to adult care reduces hospitalizations for sickle cell patients

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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