Precision Medicine News and Research

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Genetic sequencing shows promise as first-tier newborn screening test

Newborn screening (NBS) is routinely performed across the world using biochemical testing methods. Recent advancements in genetic sequencing are a potential game-changer for newborn screening, swiftly assessing a comprehensive range of monogenic disorders.

14 Sep 2023

JAX offers a fully validated, clinical whole genome sequencing test

Until quite recently, it was extremely difficult to detect the variants underlying many genetic disorders. In the absence of a defined cause, clinicians have little to guide treatment for those left without a genetic diagnosis, forcing patients and families to embark on a diagnostic odyssey with no guarantee of finding answers.

14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

Cerba HealthCare, a leading global player in medical diagnosis, today announced it has acquired CIRION BIOPHARMA RESEARCH INC

From Cerba Research 11 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Researchers investigated the complexity of polypharmacy and whether frequent dose adjustments were required for co-medications and drug pairs in hospital settings.

7 Sep 2023

Myriad Genetics survey: Women have widespread confusion and misconceptions about ovarian cancer screening

Myriad Genetics, Inc., a leader in genetic testing and precision medicine, today revealed new nationwide survey results indicating widespread confusion and misconceptions about ovarian cancer screening among a majority of women.

7 Sep 2023

New device can help test treatments in patients with gliomas

The shape and size of a grain of rice, the new device can conduct dozens of experiments at once to study the effects of new treatments on some of the hardest-to-treat brain cancers.

7 Sep 2023

New consensus statement provides guidance for use of 177Lu-PSMA radionuclide therapy in mCRPC patients

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement to provide standardized guidance for the selection and management of metastatic castrate-resistant prostate cancer (mCRPC) patients being treated with 177Lu-PSMA radionuclide therapy.

5 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

Scientists reclassify 200 rare immune system disorders using network-based approach

Scientists at CeMM, Max Perutz Labs, and St. Anna Children's Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders.

1 Sep 2023

American Heart Association releases new policy guidance for patient data collection

In an ever-evolving world of big data, more powerful analytics, and the application of artificial intelligence fueled in part by consumer, research and patient data, the American Heart Association, a global force for longer, healthier lives free of heart disease and stroke, has released new policy guidance for the collection, storage, ethical use and sharing of patient data.

30 Aug 2023

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

A team of researchers from Yale University and other institutions globally has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.

29 Aug 2023

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

University of Michigan researchers have discovered that the same cellular mechanism involved in a form of cystic fibrosis is also implicated in a form of a rare disease called cystinosis.

28 Aug 2023

Genetics and environment influence immune responses to SARS-CoV-2

During the COVID-19 pandemic, the clinical spectrum observed among people infected with SARS-CoV-2 ranged from asymptomatic carriage to death.

24 Aug 2023

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

ASD, a complex neurodevelopmental disorder, is known to be linked to altered brain development. However, precise markers that can accurately diagnose ASD at the individual level have been elusive.

24 Aug 2023

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Study investigates the impact of rapid genome sequencing for infantile epilepsy

Epilepsy in infants ranges in severity and can leave caregivers with questions about their child's health. While genetic testing to help determine the cause of epilepsy is possible, comprehensive testing does not always happen routinely and it can take a long time, leaving families waiting for answers.

17 Aug 2023

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular 'ZIP code' in the lungs.

16 Aug 2023

Precision Medicine News and Research

Genetic sequencing shows promise as first-tier newborn screening test

JAX offers a fully validated, clinical whole genome sequencing test

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Myriad Genetics survey: Women have widespread confusion and misconceptions about ovarian cancer screening

New device can help test treatments in patients with gliomas

New consensus statement provides guidance for use of 177Lu-PSMA radionuclide therapy in mCRPC patients

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Scientists reclassify 200 rare immune system disorders using network-based approach

American Heart Association releases new policy guidance for patient data collection

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

Genetics and environment influence immune responses to SARS-CoV-2

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Specific alterations in brain structural connectivity may be an early diagnostic marker for ASD

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Study investigates the impact of rapid genome sequencing for infantile epilepsy

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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