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Doctors advocate fresh efforts to combat Chagas disease, a silent killer

When Maira Gutiérrez was diagnosed with Chagas disease in 1997, neither she nor her primary care physician had even heard of the malady. She discovered her illness only by chance, after participating in a Red Cross blood drive organized by her employer, Universal Studios.

22 Aug 2023

Study finds no link between short-term immunosuppressant use and cancer

Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published today in the journal BMJ Oncology.

21 Aug 2023

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

18 Aug 2023

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

18 Aug 2023

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

Cleveland Clinic London is the first hospital in London to successfully perform a total knee replacement procedure with the assistance of an augmented reality-based surgical platform that was designed with artificial intelligence and machine learning.

18 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Deep brain stimulation shows promise for post-stroke rehabilitation

A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.

14 Aug 2023

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Transplant recipients must take life-long immunosuppressive medications to prevent rejection, but these drugs can compromise the effectiveness of vaccines.

11 Aug 2023

Diverse gut microbiome may help children survive stem cell transplant

Researchers in Italy have shown for the first time that among children who have undergone a donor stem cell transplant, the presence of diverse species of micro-organisms in the intestinal tract before the transplant resulted in significantly better overall patient survival and fewer complications.

10 Aug 2023

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

In the ongoing search for a cure for Alzheimer's disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system.

9 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications.

1 Aug 2023

Three doses of mRNA vaccine provide good protection for vulnerable people

Even vulnerable people, who are at risk of severe Covid-19, achieved good antibody levels after three doses of mRNA vaccine.

1 Aug 2023

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

Study examined the role of plasma metagenomic next-generation sequencing.

1 Aug 2023

New technology could revolutionize treatment for age-related macular degeneration

Scientists have found a way to use nanotechnology to create a 3D 'scaffold' to grow cells from the retina –paving the way for potential new ways of treating a common cause of blindness.

28 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Home sweet parking lot: Some hospitals welcome RV living for patients, families, and workers

Jim Weaver has had two major surgeries in the past decade: one to remove cancerous tumors from his bladder and another to clear a blocked artery.

27 Jul 2023

Transplant News and Research

Doctors advocate fresh efforts to combat Chagas disease, a silent killer

Study finds no link between short-term immunosuppressant use and cancer

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

A new Medicare proposal would cover training for family caregivers

Pig kidney xenotransplantation continues to function well after 32 days

Deep brain stimulation shows promise for post-stroke rehabilitation

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Diverse gut microbiome may help children survive stem cell transplant

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

UCLA study finds new way to protect livers during transplantation

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Three doses of mRNA vaccine provide good protection for vulnerable people

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

New technology could revolutionize treatment for age-related macular degeneration

New gene editing approach could revolutionize the treatment of blood disorders

Home sweet parking lot: Some hospitals welcome RV living for patients, families, and workers

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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