Antigen News and Research

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New high-throughput approach yields libraries of probes for immunological assays

An immunological test known as a "tetramer assay" can detect T cells in a blood sample that recognize a specific antigen.

20 Apr 2020

Death rates from prostate cancer predicted to decline overall in EU

Death rates from prostate cancer are predicted to fall in 2020 in the EU, largely due to better diagnosis and treatment.

17 Apr 2020

Blood test may aid in early detection of pancreatic cancer

A blood test may be able to detect the most common form of pancreatic cancer while it is still in its early stages while also helping doctors accurately stage a patient's disease and guide them to the appropriate treatment.

16 Apr 2020

Blood test may help doctors catch pancreatic cancer early

A blood test may be able to detect the most common form of pancreatic cancer while it is still in its early stages.

16 Apr 2020

'Chaperone protein' protects against autoimmune diseases, mice study shows

Like a parent of teenagers at a party, Mother Nature depends on chaperones to keep one of her charges, the immune system, in line so that it doesn't mistakenly attack normal cells, tissues and organs in our bodies.

15 Apr 2020

Temple researchers receive NIAID grant to study immunological synapse formation

Switching immune cells on is a critical step in combating infection. In the case of T cells, which are key players in immunity, this happens when dormant T cells circulating in the blood encounter a suspicious agent on the surface of specialized antigen-presenting cells.

14 Apr 2020

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

Mathematical model can predict patient outcomes to adaptive prostate cancer therapy

Prostate cancer is the most common malignancy among men in the United States. It is also the second most common cause of cancer-related deaths. Despite improved treatments for prostate cancer, many patients with advanced disease eventually develop drug resistance.

9 Apr 2020

GlobalData: Rapid POC tests to accelerate testing capacity for diagnosing COVID-19

There is a current worldwide lack of testing capacity for the novel coronavirus (COVID-19) outbreak. The frontline response for diagnosing COVID-19 has been polymerase chain reaction (PCR) testing.

3 Apr 2020

OXGENE and The Native Antigen Company Announce Collaboration to Increase COVID-19 Antigen Production for Diagnostic Kits and Vaccine Development

OXGENE™ and The Native Antigen Company today announced a collaboration to scale up production of SARS-CoV-2 (COVID-19) reagents.

2 Apr 2020

Majority of patients with mantle cell lymphoma may benefit from CAR T-cell therapy KTE-X19

A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy.

1 Apr 2020

Putting an end to the pandemic

From the plagues of medieval Europe to the influenza pandemic of 1918, the specter of the next public health disaster has gripped the minds of scientists, captivated the imaginations of writers and vexed conspiracy theorists.

1 Apr 2020

New collaboration may lead to future clinical trials to test treatment for leukemia

In a new pre-clinical study published this week in the journal Leukemia, the research team of Children's Hospital Los Angeles investigator Hisham Abdel-Azim, MD, MS, worked with colleagues to engineer T-cells to identify and target multiple sites on acute lymphoblastic leukemia cells instead of just one. The early collaboration points the way to future clinical trials to test the therapy.

1 Apr 2020

ERC awards grants to 158 European scientists to identify effective immunotherapy strategies for cancer

The European Research Council (ERC) has announced it will support Professor Thomas Blankenstein to the tune of €2.5 million over five years. This year the ERC is awarding Advanced Grants to a total of 158 scientists across Europe.

1 Apr 2020

Novel, affordable pneumonia vaccine tested in human patients

A novel vaccine against pneumonia that is less expensive and more effective than those currently used in Brazil is being tested in human patients.

31 Mar 2020

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife.

31 Mar 2020

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

Cobra Biologics, an international CDMO for biologics and pharmaceuticals, and the Karolinska Institutet, one of the world’s leading medical universities, today announced they have been awarded €3 million emergency funding by Horizon 2020 for research and development, and phase I clinical trial testing of a DNA vaccine against COVID-19, as part of the OPENCORONA consortium to support global efforts tackling the pandemic.

31 Mar 2020

Researchers discover new way to refine production of retinal cells to treat blindness

Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly.

30 Mar 2020

Microbiome could help identify pre-cancer risk in women with HPV

A new study published in the open-access journal PLOS Pathogens in March 2020 reports the possible use of the bacteria Gardnerella found in the cervix and vagina of women with Human papillomavirus (HPV) infection, as a marker of precancerous change. The findings could help to find new methods of treatment that involve inducing changes in the microbiome to arrest the course of the disease.

26 Mar 2020

Advancing CAR T-cell therapy for treatment of solid tumors

The full title of the research is "The study of the mechanisms of effectiveness of T-cells CAR-T towards solid tumors"; it was supported by nonprofit RakFond (Cancer Fund) and CyStoreLab (a resident of Skolkovo).

25 Mar 2020

Antigen News and Research

New high-throughput approach yields libraries of probes for immunological assays

Death rates from prostate cancer predicted to decline overall in EU

Blood test may aid in early detection of pancreatic cancer

Blood test may help doctors catch pancreatic cancer early

'Chaperone protein' protects against autoimmune diseases, mice study shows

Temple researchers receive NIAID grant to study immunological synapse formation

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

Mathematical model can predict patient outcomes to adaptive prostate cancer therapy

GlobalData: Rapid POC tests to accelerate testing capacity for diagnosing COVID-19

OXGENE and The Native Antigen Company Announce Collaboration to Increase COVID-19 Antigen Production for Diagnostic Kits and Vaccine Development

Majority of patients with mantle cell lymphoma may benefit from CAR T-cell therapy KTE-X19

Putting an end to the pandemic

New collaboration may lead to future clinical trials to test treatment for leukemia

ERC awards grants to 158 European scientists to identify effective immunotherapy strategies for cancer

Novel, affordable pneumonia vaccine tested in human patients

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Cobra Biologics and Karolinska Institutet join forces to develop DNA vaccine against COVID-19

Researchers discover new way to refine production of retinal cells to treat blindness

Microbiome could help identify pre-cancer risk in women with HPV

Advancing CAR T-cell therapy for treatment of solid tumors

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