Colon News and Research

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Longer looks: Rushed medicine; Exercising your way to a smarter brain

Something in the world of medicine is seriously amiss. Unhappy patients gripe about their doctors' brusque manner and give them bad marks on surveys and consumer websites like HealthGrades and Angie's List. They tell tales of being rushed out of the office by harried doctors who miss crucial diagnoses, never look up from their computers during an exam, make errors in prescriptions, and just plain don't listen to their patients. ... And things don't seem much better from the other side of the stethoscope.

20 Apr 2012

ACS report outlines gaps and opportunities that contribute to cancer mortality

An annual report from the American Cancer Society says much of the suffering and death from cancer could be prevented by more systematic efforts to reduce tobacco use, improve diet and physical activity, reduce obesity, and expand the use of established screening tests. The report, Cancer Prevention and Early Detection Facts and Figures (CPED), outlines gaps and opportunities that contribute to cancer mortality, and says social, economic, and legislative factors profoundly influence individual health behaviors.

20 Apr 2012

Gut microbiota plays a causal role in development of diabetes and NAFLD

Exciting new data presented today at the International Liver Congress 2012 shows the gut microbiota's causal role in the development of diabetes and non-alcoholic fatty liver disease (NAFLD), independent of obesity.

19 Apr 2012

Large study examines diagnostic yield of colonoscopy to investigate melena

A new study from researchers in Oregon reports that the diagnostic yield of colonoscopy to investigate melena after a nondiagnostic upper endoscopy is lower, 4.8 percent, than previously reported. The rate of therapeutic intervention in this population is very low; therefore, patients with melena and a nondiagnostic upper endoscopy who are stable and without evidence of ongoing bleeding may be able to safely undergo elective colonoscopy.

18 Apr 2012

New study recommends intraoperative histological evaluation for Hirschsprung disease treatment

Hirschsprung disease occurs when nerve cells in the colon do not develop normally before birth and the bowel is unable to move its contents along. Severe bowel obstruction and even perforation can then occur. The condition is usually diagnosed within the first months of life, but can be found in older children as well.

18 Apr 2012

ACS, CDC partner to improve surgical patient safety

A joint, strategic partnership to improve surgical patient safety at the national level was announced today by leaders of the American College of Surgeons (ACS) and the Centers for Disease Control and Prevention.

17 Apr 2012

More than one third of patients with invasive cancer are undertreated for their pain

More than one third of patients with invasive cancer are undertreated for their pain, with minorities twice as likely to not receive analgesics, according to research from The University of Texas MD Anderson Cancer Center.

17 Apr 2012

Immunotherapy may also help elderly cancer patients

Cancer is much more likely in the elderly than the young, and their bodies often are less prepared to fight the disease and the often-toxic side effects of treatment.

16 Apr 2012

Researchers identify new mechanism by which colon cancer develops

A team of researchers at Case Western Reserve University School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on segments of DNA located between genes, or so-called "junk DNA," the team has discovered a set of master switches, i.e., gene enhancer elements, that turn "on and off" key genes whose altered expression is defining for colon cancers.

16 Apr 2012

Missing tool helps sperm and eggs develop exactly 23 chromosomes each

Researchers at the University of California, Davis have discovered a key tool that helps sperm and eggs develop exactly 23 chromosomes each. The work, which could lead to insights into fertility, spontaneous miscarriages, cancer and developmental disorders, is published April 13 in the journal Cell.

16 Apr 2012

Natural products isolated from marine mollusks and sponges can reverse multidrug resistance in cancer cells

Many marine natural products show anticancer activity, but some can reverse multidrug resistance in cancer cells. A new investigation by Robert J. Capon of the University of Queensland correlates the products' structures with their activity.

12 Apr 2012

Research explores power of offering colon cancer screening options

Researchers find that when given a choice of methods, more people will opt to get screened for colon cancer. Meanwhile, a separate study found that insurance coverage of lung cancer screenings for high-risk patients could prevent -- at a low cost -- thousands of deaths annually.

12 Apr 2012

Low-dose spiral CT cost-effective in reducing lung cancer deaths

Lung cancer is the most lethal cancer in the United States. According to the National Cancer Institute, lung cancer causes more than 150,000 deaths annually and has a survival rate of 16 percent. More Americans die of lung cancer each year than of cervical, breast, colon and prostate cancers combined.

10 Apr 2012

State roundup: Health costs cloud forecast for state budgets; Minnesota to use HMO refund on personal care

U.S. state and local governments' fiscal situations have improved recently but will still deteriorate through 2060, the Government Accountability Office said on Thursday. ... The outlook remains gloomy for the future, with healthcare costs, both for public employees and for the Medicaid insurance program for the poor, swelling and weighing on budgets, GAO said.

7 Apr 2012

FDA alerts on fake cancer drug imports

This week, the U.S. Food and Drug Administration (FDA) alerted healthcare professionals that 120 vials of fake cancer drug Altuzan - which contained no active ingredient - had entered the U.S from distributors in the U.K. after being purchased from wholesalers in Turkey.

5 Apr 2012

Anti-ceramide antibody may prevent radiation gastrointestinal syndrome

A new study offers the first evidence of a drug capable of preventing lethal damage to the gastrointestinal (GI) tract caused by exposure to high levels of ionizing radiation, such as those occurring during a nuclear incident.

5 Apr 2012

Negative link between obesity and colon cancer screening in white women

A new study by Johns Hopkins researchers shows that obese white women may be less likely than normal-weight counterparts and African-Americans of any weight or gender to seek potentially lifesaving colon cancer screening tests.

5 Apr 2012

More than 4 in 10 people at high risk for hereditary pancreatic cancer have small lesions

A team of scientists led by Johns Hopkins researchers have found that more than four in 10 people considered at high risk for hereditary pancreatic cancer have small pancreatic lesions long before they have any symptoms of the deadly disease.

5 Apr 2012

Anti-TAK1 agents may hold hope against highly aggressive KRAS mutant colon cancers

Anurag Singh, PhD, assistant professor in the Department of Pharmacology and Experimental Therapeutics at Boston University School of Medicine has been invited to present his recent work on targeted therapeutics for colon cancer at the American Association of Cancer Research Annual Meeting in Chicago, IL.

4 Apr 2012

Drugs that target cholesterol pathway may enhance cancer-killing potential of chemotherapy drugs

Johns Hopkins investigators are testing a way to use drugs that target a cholesterol pathway to enhance the cancer-killing potential of standard chemotherapy drugs. Their tests, in mouse models of pancreatic cancer, may yield new and more effective combinations of current and possibly new anti-cancer drugs.

4 Apr 2012