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Multimarker molecular stool test for colon cancer unaffected by medication, lifestyle factors

Research on an investigational DNA methylation test for colorectal cancer demonstrated that the only clinical variable that influenced test results was age, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4.

4 Apr 2012

Researchers discover two optimal gene targets for new colorectal cancer test

A study presented today by Mayo Clinic researchers at the American Association for Cancer Research (AACR) Annual Meeting 2012 in Chicago identified two genes that are optimal targets to be analyzed in a new noninvasive test for colorectal cancer developed by Mayo Clinic, in collaboration with Exact Sciences Corporation.

4 Apr 2012

Many RA patients more likely to develop lower GI disease

Add lower gastrointestinal (GI) problems such as ulcers, bleeding and perforations to the list of serious complications facing many rheumatoid arthritis patients. They are at greater risk for GI problems and gastrointestinal-related death than people without the disease, a Mayo Clinic study shows.

4 Apr 2012

MEK1 mutation does not necessarily make BRAF mutant melanomas resistant to inhibitors

A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true.

2 Apr 2012

CT scans more effective than traditional lung cancer detection methods

A new study led by researchers at Mount Sinai School of Medicine indicates that CT scans are more effective than traditional lung cancer detection methods at identifying aggressive lung cancers in their most treatable stages.

31 Mar 2012

Diversity of intestinal stem cells is greater than previously thought

Tales from the crypt are supposed to be scary, but new research from Vanderbilt University, the HudsonAlpha Institute for Biotechnology and colleagues shows that crypts can be places of renewal too: intestinal crypts, that is. Intestinal crypts are small areas of the intestine where new cells are formed to continuously renew the digestive tract. By focusing on one protein expressed in our intestines called Lrig1, the researchers have identified a special population of intestinal stem cells that respond to damage and help to prevent cancer.

31 Mar 2012

UH clinical trial to evaluate stool DNA testing for colon cancer

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals (UH) Case Medical Center's Seidman Cancer Center and Case Western Reserve University School of Medicine are studying a promising new non-invasive technology for colon cancer screening. The four-year study is recruiting patients to compare the effectiveness of stool DNA (SDNA) testing with colonoscopy for detecting large colon polyps.

31 Mar 2012

Elective endovascular aneurysm repair benefits men more than women

A study published in the April issue of Journal of Vascular Surgery reports that women derive less benefit than men from elective endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAA's). The research was done at The Vascular Group, The Institute for Vascular Health and Disease, Albany Medical College, The Center for Vascular Awareness Inc., in Albany, NY.

31 Mar 2012

Researchers identify new population of intestinal stem cells

Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer.

30 Mar 2012

Aspirin lowers risk for cancers: Meta analysis

Aspirin has multiple benefits. It is a painkiller whose origins can be traced to Hippocrates, reduces the chances of developing or dying from cancer earlier than previously thought and also prevents tumors from spreading, studies show.

28 Mar 2012

Improper preparation for colonoscopy hides pre-cancerous polyps

What happens on the day before a colonoscopy may be just as important as the colon-screening test itself.

28 Mar 2012

Therapy Finder - Colorectal Cancer app now available for patients

No one wants to hear the words, "you have colon cancer." For patients diagnosed with an advanced form of the disease, these words can be particularly devastating. The five-year survival rate can be a little as 6 percent. The top-of-mind question becomes, "Which treatment or clinical trial will work for me?"

28 Mar 2012

National Colon Cancer Awareness Month attempts to widen screening efforts

March is the National Colon Cancer Awareness Month and to mark it Ferrell Hospital and Harrisburg Medical Center have teamed up with the American Cancer Society to provide free take-home colon cancer tests to anyone who is interested.

25 Mar 2012

Victoria’s Goldfields region linked to higher risk of cancer

University of Melbourne's Dr Dora Pearce is urging for more testing of soil and water in central Victoria's Goldfields region to address the possible threat of cancer caused by arsenic. She has worked on research examining the link between elevated levels of arsenic caused by historic gold mining and cancer in the region.

25 Mar 2012

Researchers explain how obscurins suppress breast cancer formation

A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast.

22 Mar 2012

More colonoscopy procedures under anesthesia than expected: Study

According to researchers more patients underwent general anesthesia during gastroenterological procedures such as colonoscopy between 2003 and 2009.

21 Mar 2012

Study finds higher death rate in calorie-restricted models of IBD

In a surprising result, Michigan State University researchers looking at the effects of diet on bowel disease found that mice on a calorie-restricted diet were more likely to die after being infected with an inflammation-causing bacterial pathogen in the colon.

21 Mar 2012

Colorectal cancer screening rates higher in population with multiple morbidities

A study by University of Kentucky researchers showed that in Appalachia, colorectal cancer screening rates were higher in the population with multiple morbidities or diseases compared to those who had no morbidities at all.

21 Mar 2012

Epidemiologist examines effect of population aging on inpatient care

The effect of population aging on the number of admissions to hospital for inpatient treatment is examined by epidemiologist Enno Nowossadeck in the latest issue of Deutsches -rzteblatt International.

20 Mar 2012

Health must be taken into account in climate change mitigation strategies

Health must be taken into account in climate change mitigation strategies. It is not widely appreciated that there are many benefits to health that are likely to accrue from a low carbon economy, say experts in a special supplement published on bmj.com today.

20 Mar 2012