Immune System News and Research

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Study shows that key parts of human immunity are shared in bacteria

The human immune system, that marvel of complexity, subtlety, and sophistication, includes a billion-year-old family of proteins used by bacteria to defend themselves against viruses, scientists at Dana-Farber Cancer Institute and in Israel have discovered.

13 Jan 2022

Macrophages in the arteries can "sniff" out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

13 Jan 2022

Study finds blunted cortisol profiles in women who experienced childhood sexual abuse

Childhood sexual abuse can lead to depression, anxiety, cardiovascular disease and other health problems later in life. Not all abused children experience these problems, however, and researchers are working to understand whose health is affected and why.

13 Jan 2022

Microbial characteristics of COVID-19

To better understand how the disease progresses, a recent paper in the journal Frontiers in Medicine discusses the role of the human microbiota in this condition.

13 Jan 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Novel biomarker can be used to identify disease progression in ALS

An international collaboration led by Flinders University has identified a potential biomarker for amyotrophic lateral sclerosis, also known as Motor Neuron Disease, providing a way to test the effectiveness of future clinical trials.

13 Jan 2022

SARS-CoV-2-specific immune responses elicited by inactivated COVID-19 vaccines

In this study, researchers identified and recruited volunteers who received inactivated COVID-19 vaccines in real-world settings.

13 Jan 2022

Nanovaccines and their immunomodulatory effect against human viruses

A review ]presented the primary progress of nanovaccines against the main viral illnesses.

13 Jan 2022

Moffitt experts provide insight on the role of B cell immunity in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Long before the onset of dementia, there is evidence for increased activity of the brain's immune system. Researchers from DZNE and the University Hospital Bonn come to this conclusion based on a study of more than 1,000 older adults.

12 Jan 2022

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood-but only in men-finds a large population study published online in the Journal of Epidemiology & Community Health.

12 Jan 2022

Regrowing knee cartilage can be a promising hop toward healing joints in humans

UConn bioengineers successfully regrew cartilage in a rabbit's knee, a promising hop toward healing joints in humans, they report in the 12 January issue of Science Translational Medicine.

12 Jan 2022

UCLA-led researchers improve method that was designed to kill HIV-infected cells

In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells.

12 Jan 2022

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

A common cold may boost the immune system against COVID-19

A recent groundbreaking research paper published in the journal Nature Communications reveals the association of circulating SARS-CoV-2-specific T cells at exposure with lack of infection – implying the protective role for cross-reactive immune T cells in coronavirus disease 2019 (COVID-19) and opening the door for second-generation vaccines that could circumvent spike-antibody immune escape variants.

11 Jan 2022

New technique could allow more diseases to be safely treated by nanomedicine

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness.

11 Jan 2022

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behavior within the vessel wall.

11 Jan 2022

Engineering higher affinity SARS-CoV-2 antibodies

A new study describes the potential of engineered neutralizing antibodies that have a high affinity for the binding epitopes.

11 Jan 2022

Study opens up prospects for using virotherapy to treat central nervous system tumors

In a study conducted at the University of São Paulo's Human Genome and Stem Cell Research Center (HUG-CELL) in Brazil, serial systemic injections of zika virus into mice with brain tumors destroyed the cancer without causing neurological damage or injuring other organs, and increased the animals' survival rate.

11 Jan 2022

Immune System News and Research

Study shows that key parts of human immunity are shared in bacteria

Macrophages in the arteries can "sniff" out their surroundings and cause inflammation

Study finds blunted cortisol profiles in women who experienced childhood sexual abuse

Microbial characteristics of COVID-19

Role of leptin in immune modulation and pathophysiology of COVID-19

Novel biomarker can be used to identify disease progression in ALS

SARS-CoV-2-specific immune responses elicited by inactivated COVID-19 vaccines

Nanovaccines and their immunomodulatory effect against human viruses

Moffitt experts provide insight on the role of B cell immunity in endometrial cancer

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Study finds evidence for increased activity of the brain’s immune system long before dementia onset

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Regrowing knee cartilage can be a promising hop toward healing joints in humans

UCLA-led researchers improve method that was designed to kill HIV-infected cells

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

A common cold may boost the immune system against COVID-19

New technique could allow more diseases to be safely treated by nanomedicine

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

Engineering higher affinity SARS-CoV-2 antibodies

Study opens up prospects for using virotherapy to treat central nervous system tumors

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