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New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Decline in CT imaging during the pandemic may raise the possibility of poorer cancer outcomes

Significant decreases in CT imaging for cancer persisted even after the peak of the COVID-19 pandemic in 2020, delaying diagnosis and treatment and raising the possibility of more advanced cancers and poorer outcomes for patients in the future, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2021

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

When something disrupts hormone binding to the receptor, such as environmental compounds or pollutants, called endocrine disrupting chemicals (EDCs), the results can be harmful and, in some cases, lead to certain forms of cancer.

24 Nov 2021

How does penicillin work?

In this interview, we spoke to Dr. Bartlomiej Salamaga about his latest research that discovered how penicillin works in the body.

24 Nov 2021

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

A minimally invasive ablation procedure offers long-term relief for patients who experience chronic and debilitating pain after knee replacement surgery, according to a study being presented next week at the annual meeting of the Radiological Society of North America.

24 Nov 2021

New "image analysis pipeline" provides insight into how disease changes the body

A new "image analysis pipeline" is giving scientists rapid new insight into how disease or injury have changed the body, down to the individual cell.

24 Nov 2021

Study proves safety and effectiveness of novel radionuclide therapy for neuroendocrine neoplasms

A new type of peptide receptor radionuclide therapy (PRRT) has been shown to control disease in 85 percent of patients with metastatic neuroendocrine neoplasms, achieving complete remission in some patients.

23 Nov 2021

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Researchers at Yale University analyzing specialized MRI exams found significant changes in the microstructure of the brain's white matter in adolescents and young adults with autism spectrum disorder (ASD) compared to a control group, according to research being presented next week at the annual meeting of the Radiological Society of North America.

23 Nov 2021

Study aims to understand how prenatal factors, early life experiences influence child brain development

Cynthia Rogers, MD, visits a baby in the Newborn Intensive Care Unit at St. Louis Children's Hospital. Rogers is helping lead a national study aimed at understanding how prenatal factors and early life experiences influence brain development and behavior in infants and young children.

23 Nov 2021

AI identifies patterns on CT scans that offer new promise for treating small cell lung cancer

Researchers at the Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University have used artificial intelligence (AI) to identify patterns on computed tomography (CT) scans that offer new promise for treating patients with small cell lung cancer.

23 Nov 2021

Study shows how inadequate sleep can jeopardize brain organization in early adolescence

We all know that if we don't get enough sleep or don't sleep well, we won't be on top of our game the next day.

22 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Researchers synthesize carbon dots using different precursors and studied their antimicrobial effects in gram-negative bacteria.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

Adolescents with multiple concussions show disruption in the brain's default mode network

Adolescents and young adults with post-concussive symptoms who suffered three to five concussions showed disruption in the default mode network, an interconnected network of brain regions involved in wakeful rest and internal thoughts.

22 Nov 2021

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the mechanism behind regulated splicing of large constitutive exons which are rich in disordered regions, and their potential involvement in the assembly of transcription factors.

21 Nov 2021

Imaging News and Research

New technique may be a significant leap forward in the understanding of human cells

Decline in CT imaging during the pandemic may raise the possibility of poorer cancer outcomes

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

How does penicillin work?

Minimally invasive ablation procedure offers long-term relief after knee replacement surgery

New "image analysis pipeline" provides insight into how disease changes the body

Study proves safety and effectiveness of novel radionuclide therapy for neuroendocrine neoplasms

Adolescent and young adult ASD patients show changes in the brain's white matter microstructure

Study aims to understand how prenatal factors, early life experiences influence child brain development

AI identifies patterns on CT scans that offer new promise for treating small cell lung cancer

Study shows how inadequate sleep can jeopardize brain organization in early adolescence

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Adolescents with multiple concussions show disruption in the brain's default mode network

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

Washington University joins international effort to support data science research and training in Africa

New study uncovers a mechanism of sleep in zebrafish

Using PET scans to predict recurrence in Hodgkin lymphoma

Novel technique solves structure of the HIV capsid alone and in complex with host factors

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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