Colon News and Research

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Colonoscopic FMT effective in treating IBD, C.difficile-associated diarrhea

Growing evidence for the effectiveness of fecal microbiota transplants as a treatment for patients with recurrent bouts of Clostridium difficile (C.difficile) associated diarrhea is presented in three studies -- including a long-term follow-up of colonoscopic fecal microbiota transplant (FMT) for recurrent C. difficile Infection that included 77 patients from five different states-- unveiled today at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC.

1 Nov 2011

Aspirin may reduce risk of bowel cancer by half: Study

According to a new study published in The Lancet, a regular dose of aspirin may not only stave off heart disease but also cut the risk of developing hereditary cancer in half.

31 Oct 2011

Focused training increases physician's ability to find potentially precancerous polyps

Just two extra hours of focused training significantly increased the ability of physicians to find potentially precancerous polyps, known as adenomas, in the colon, according to researchers at Mayo Clinic in Florida. These findings suggest that new methods to educate endoscopists, the physicians who examine the colon, could increase colorectal cancer detection rates and potentially reduce cancer deaths.

31 Oct 2011

UV light exposure and vitamin D play a potential role in chronic digestive conditions

New research points to a potential role for UV light exposure and vitamin D levels in chronic digestive conditions; Crohn's disease, a serious inflammatory condition in the small intestine; and ulcerative colitis (UC), which similarly affects the colon.

31 Oct 2011

GC-C agonists have potential to delay progression of colitis into colon cancer

Synergy Pharmaceuticals, Inc., a developer of new drugs to treat gastrointestinal (GI) disorders and diseases, today announced that poster P409 presented at the upcoming 2011 annual scientific meeting of the American College of Gastroenterology highlights the potential use of guanylate cyclase-C agonists to delay progression of colitis into colon cancer.

31 Oct 2011

Fat cells play a major role in mediating ovarian cancer metastasis

A large pad of fat cells that extends from the stomach and covers the intestines provides nutrients that promote the spread and growth of ovarian cancer, reports a research team based at the University of Chicago in the journal Nature Medicine, published online October 30th, 2011.

31 Oct 2011

Research roundup: Medicaid's long-term care bill; work-based coverage and the health law

This study examined Medicare data on beneficiaries diagnosed with colorectal cancer between 1995 and 2005 who ranged from 67 to 85 years old. The authors found, "Medicare beneficiaries with colon cancer had better outcomes if they had more primary care utilization before diagnosis. Even within this universally insured population, 28% of Medicare beneficiaries with colon cancer had no or only 1 contact with primary care physicians in the 3 to 27 months before the diagnosis.

29 Oct 2011

ZIOPHARM reports promising preclinical data with palifosfamide in pediatric sarcoma model

ZIOPHARM Oncology, Inc., a drug development company employing small molecule and synthetic biology approaches to cancer therapy, today announced the presentation of promising preclinical data with palifosfamide in a pediatric sarcoma model.

29 Oct 2011

Two new studies could provide tools to prevent rehospitalizations after major surgeries

Studies have shown that patients returning to the hospital soon after they've been discharged may cost Medicare up to billions of dollars each year, but two new studies presented at the 2011 Annual Clinical Congress of the American College of Surgeons could give surgical teams and their patients tools to prevent rehospitalizations.

28 Oct 2011

BROCA test identifies 12 gene mutations linked to ovarian and related cancers

More patients with ovarian carcinoma carry cancer-predisposing mutations, and in more genes, than previously thought.

27 Oct 2011

Patients with HIV are not being screened enough for cancers: Study

According to a latest study finding presented at the Infectious Diseases Society of America 49th Annual Meeting, patients with HIV were less likely to have routine screening for breast, cervical and colon cancer compared with patients without HIV.

26 Oct 2011

Coffee may protect against a slow growing skin cancer: Study

A new study shows that drinking coffee was associated with decreased risk of a common and slow-growing form of skin cancer called basal cell carcinoma.

25 Oct 2011

NCI awards Metabolomx SBIR contract to develop sensor array system for detecting lung cancer

Metabolomx, a diagnostic company focused on breath analysis for the detection of cancer, today announced the Company was awarded a Small Business Innovation Research (SBIR) contract by the National Cancer Institute (NCI). The $1.14 million combined Phase I/II Fast-Track contract will support the research and development of Metabolomx' sensor array system to detect lung cancer.

24 Oct 2011

Six prominent surgeons receive ACS' Honorary Fellowship

Honorary Fellowship in the American College of Surgeons (ACS) was awarded to six prominent surgeons from South Africa, England, Ireland, Italy, The Netherlands, and the People's Republic of China last night during Convocation ceremonies that preceded the official opening of the College's 97th Annual Clinical Congress.

24 Oct 2011

HCI researchers discover new way to model human breast cancer

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have discovered a new way to model human breast cancer that could lead to new tools for predicting which breast cancers will spread and new ways to test drugs that may stop its spread.

24 Oct 2011

Fecal immunochemical testing an inexpensive alternative to colonoscopy

Eventually, colon cancers bleed and so tests for blood in stool seem an inexpensive and noninvasive alternative to traditional colonoscopies. In fact, a recent article in the journal Cancer Prevention Research showed that fecal immunochemical testing (FIT) is an accurate predictor of colorectal cancer and can provide a low-cost screening alternative for medically underserved populations.

21 Oct 2011

Two Philadelphia scientists to receive John Scott Award

Two internationally recognized scientists with strong Philadelphia ties are to receive the John Scott Award this year.

21 Oct 2011

Colon cancer may be linked to a bacterium that causes appendicitis and gum disease: Study

A new study shows that a bacterium that causes appendicitis and gum disease is also found in colon tumors. Researchers suggest that it may set the stage for colorectal cancer, the second-deadliest malignancy. The bacterium – fusobacterium might play a role in determining the prognosis of colorectal cancers and shaping their treatment, according to two research teams independently reporting a relationship between the rod-shaped microbe and cancers of the lower digestive system.

18 Oct 2011

Study identifies SIRT2 tumor suppressor protein linked to cancer

The list of aging-associated proteins known to be involved in cancer is growing longer, according to research by investigators at Vanderbilt-Ingram Cancer Center and the National Institutes of Health.

18 Oct 2011

Scientists discover high levels of Fusobacterium in colorectal cancers

Scientists at Dana-Farber Cancer Institute and the Broad Institute have found strikingly high levels of a bacterium in colorectal cancers, a sign that it might contribute to the disease and potentially be a key to diagnosing, preventing, and treating it.

18 Oct 2011