Immune System News and Research

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Immune cells in the liver eat up excess cholesterol, study reveals

A new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries.

11 Mar 2024

Researchers develop precise drugs to target HIV's Nef protein

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

9 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Sleep boosts immune cell mobility toward lymph nodes

Researchers at LMU Munich have shown that sleep enhances the migratory potential of T cells toward lymph nodes.

8 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

Common age-associated changes in the blood found to be a risk factor for acute kidney injury

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults worldwide.

7 Mar 2024

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

Metal organic frameworks enhance immune response in experimental vaccine

Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins.

6 Mar 2024

Simulation model predicts optimal COVID-19 booster frequency

Patients kept asking a question that Nathan Lo, MD, PhD, infectious disease specialist, had a hard time answering: How often should I get my booster shot for COVID-19?

6 Mar 2024

Can postbiotics improve athletic performance and recovery?

Researchers describe the utility of postbiotics in improving exercise performance and recovery.

6 Mar 2024

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Cervical cancer is among the most common malignancies affecting women worldwide. In 2020 alone, approximately 600,000 women were diagnosed with this disease, and over 314,000 died from it.

5 Mar 2024

Researchers examine the immune response of a hypervaccinated individual

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen have examined a man who has received more than 200 vaccinations against Covid-19. They learned of his case via newspaper reports.

5 Mar 2024

Researchers take important step toward genetic therapy for hereditary conditions

Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.

5 Mar 2024

COVID booster in lactating mothers can provide antibodies for infants

Lactating mothers who get the COVID-19 booster pass along the antibodies to their children via their breast milk – and potentially protect babies too young to receive the vaccine, a study from the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) and the UF College of Medicine found.

4 Mar 2024