Transfection News and Research

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Pretreating a vein graft with edifoligide prior to coronary bypass graft surgery does not lower the rate of graft failure

Coronary artery bypass graft (CABG) surgery is one of the most common surgical procedures performed in the United States, according to background information in the article. In appropriately selected patients, CABG surgery results in improved survival, relief of angina, and improved quality of life. Despite frequent use of artery grafts, vein grafts remain the most frequently used conduit.

13 Nov 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Scientists discover breakthrough method to treat neuronal diseases

What do stroke, epilepsy, head or spinal cord trauma, Parkinson’s disease and Alzheimer’s disease patients have in common? They all suffer from neuronal cell death brought about by the absence or malfunction of specific genes.

30 Aug 2004

Cyntellect issued patent covering LaserFect(TM) technology

Cyntellect a privately-held biotechnology company, has announced the issuance of U.S. Patent No. 6,753,161 covering the Company's LaserFect(TM) technology.

6 Aug 2004

New gene-silencing technique

A new gene-silencing technique that takes place in the nucleus of human cells, has been demonstrated by researchers at the University of California, San Diego (UCSD) School of Medicine and the VA San Diego Healthcare System.

5 Aug 2004