Laboratory News and Research

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Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005

Eat your way to a better brain for your baby

A team of British scientists at Manchester and Lancaster Universities has turned established thinking on its head in a bid to understand the serious and often deadly condition, hydrocephalus, commonly known as 'water on the brain'.

From The University of Manchester 28 Nov 2005

Cranberry flavoured toothpaste may help stop decay

According to researchers cranberries, well-known for their ability to help thwart urinary tract infections, may also help prevent tooth decay and cavities.

28 Nov 2005

MGH study finds first function for, promising flexibility in adult-born nerve cells

New brain cells that develop in the olfactory system of adult mice appear to play a role in the brain different from that of older neurons.

28 Nov 2005

New method to discover links between cellular machines

Most of what happens in cells is the work of machines that contain dozens of molecules, chiefly proteins. With the completion of human and other genomes, researchers now have a nearly complete "parts list" of such machines; what's lacking now is the manual telling where all the pieces go.

28 Nov 2005

GRK5's role in restenosis

Researchers at Jefferson Medical College have begun to clarify the role of a protein - and potential drug target - in the process by which arteries re-clog after treatment.

28 Nov 2005

Coaxing human embryonic stem cells to make dopamine

For all of the promise embryonic stem cells hold for therapies for neurodegenerative diseases such as Parkinson's disease, they are notoriously difficult to use.

28 Nov 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

Skinphysical (skin damage test) launched in UK

A world-first test that assesses the damage people have done to their skin through sun exposure is being launched to the public at clinics throughout the UK.

26 Nov 2005

Researchers gain detailed view yet of the heart of the translocon

Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. The process of transporting proteins across or into membranes is a critical function that occurs in every cell.

26 Nov 2005

Cellular clues to vitamin A resistance in lung cancer

Vitamin A deficiency has been associated with the development of lung cancer in laboratory studies. However, clinical trials of natural and synthetic derivatives of vitamin A, called retinoids, for the prevention of lung cancer have been largely unsuccessful in the general population.

26 Nov 2005

Updated guidelines for diagnosing multiple sclerosis

An international panel of neurologists has updated the current guidelines for diagnosing multiple sclerosis (MS), strengthening the role of magnetic resonance imaging (MRI).

26 Nov 2005

Tuberculosis research

It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths.

26 Nov 2005

Fear gene discovered

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger.

26 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Newly identified protein may help improve treatment for lung cancer

Researchers hope that a newly identified protein can one day help improve treatment for lung cancer. The findings are reported by researchers from Wake Forest University School of Medicine and colleagues in the Journal of the National Cancer Institute.

21 Nov 2005

Nanotechnology and biochemistry provide new way to study T cell signaling

Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley, combining nanotechnology with biochemistry, have created unique synthetic membranes that, for the first time ever, enable them to directly control signaling activity in living T cells from the immune system. Already their experiments have yielded surprising results.

21 Nov 2005

Scientist finds first evidence of a living memory trace

An international team of scientists for the first time has detected a memory trace in a living animal after it has encountered a single, new stimulus.

21 Nov 2005

Warning labels on high-risk drugs ignored by doctors

In a survey of approximately 930,000 ambulatory care patients, researchers from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care) and colleagues found that 42 percent received prescriptions for drugs with Black Box Warnings (BBW), the Food and Drug Administration's strongest label for high-risk medication.

21 Nov 2005