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Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Significant new breakthroughs in understanding how the genes in mammals are controlled

An international consortium of genome research institutes and investigators, including Jackson Laboratory Staff Scientists Carol J. Bult, Ph.D., and Martin Ringwald, Ph.D., has reported significant new breakthroughs in understanding how the genes in mammals are controlled.

6 Sep 2005

New ways to enhance or block fertilization

Researchers have capitalized on the unique properties of a sperm cell to follow cell membrane fusion as it occurs during fertilization, tracking the full cascade of events for the first time. The findings could reveal new ways to enhance or block fertilization, as well as how to control the secretion of neurotransmitters and hormones such as insulin.

6 Sep 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

Human tissue grown from stem cells, available for transplant in the next four years

A team of researchers from the University of Liverpool in the UK have embarked on an ambitious project which could see human tissue grown from stem cells, available for transplant in the next four years.

5 Sep 2005

Gene B-myb essential in preventing tumors

A new study has confirmed that research done with zebrafish may be able to play a critical role in learning about the genetic basis of cancer and the mutations that can lead to it - and identified one gene in particular, B-myb, whose function is essential to preventing tumors.

5 Sep 2005

Single molecular anchor holds the key to treating many types of bacterial meningitis

By blocking the molecule's anchoring ability, researchers may be able to find a way to stave off the most common serious infection of the central nervous system and a major cause of childhood death and disability. The researchers' findings appear in the September 2005 issue of the Journal of Clinical Investigation.

5 Sep 2005

Parasite could help prevent asthma

Asthma in Britain has reached epidemic proportions and the country now has one of the highest numbers of sufferers of the allergy in the world; in Ireland alone it is reported that as many as 30% of all schoolchildren have symptoms of the disease.

5 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

UK fertility specialist and broadcaster says embryonic stem cell research promises are hyped up

According to a well known fertility specialist and broadcaster in the UK, the promise of embryonic stem cell research has been oversold by scientists.

5 Sep 2005

New understanding of how our genome works to produce a complex organism like a human being

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

4 Sep 2005

Is the disease course of rheumatoid arthritis becoming milder?

Rheumatoid arthritis (RA) is a chronic inflammatory disease, marked with joint pain and erosion. The course of RA can vary considerably, from mild to crippling, and is difficult to predict.

4 Sep 2005

New key evidence supports claims that some types of cancer originate with defects in stem cells

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells.

4 Sep 2005

New drug will help fight against superbugs

In the fight against the infections invading hospitals both sides of the globe, scientists have developed a drug that destroys the defences of superbugs, raising hopes it could help quell the rampant and often lethal outbreaks that continue to strike hospitals.

4 Sep 2005

Naturally occurring peptide hormones - candidates for the treatment of cancer, sexual dysfunction, eating disorders

Chemists at the University of Arizona have developed modified versions of naturally occurring peptide hormones that could be key to novel treatments of a variety of diseases, including eating disorders (anorexia, obesity), diabetes, sexual dysfunction and skin cancer.

1 Sep 2005

Molecular switch that turns on the production of myelin

Scientists at New York University School of Medicine report in a new study that they have identified the molecular switch that turns on the production of myelin, the fatty insulation around nerve cells that ensures swift and efficient communication in the nervous system.

1 Sep 2005

Potential new way to fight HIV

Researchers have confirmed for the first time the benefit of an innate defense system present in the few patients who remain healthy after years of infection with HIV despite receiving no treatment, according to an article published in the September edition of the Journal of Virology.

1 Sep 2005

C. elegans worm provides clues to dealing with human disease

A step towards understanding cell mutations that cause a variety of human diseases, particularly in children -- including that which brings about premature aging and early death -- has been taken by researchers at the Hebrew University of Jerusalem Silberman Institute of Life Sciences and the John Hopkins University School of Medicine.

1 Sep 2005

Researchers link individual preferences to neuronal activity in brain

Life is full of choices. But how do individuals know what their preferences are and how do they act on them? And what leads mothers to make choices that benefit or lead to neglect of her offspring? Based on research performed using laboratory rats, a team of neuroscience researchers at Rutgers University-Newark suggest that an intricate system exists within the brain for establishing individual preferences, which ultimately impacts choices.

1 Sep 2005

Laboratory News and Research

Human embryonic stem cell lines accumulate changes in their genetic material over time

Significant new breakthroughs in understanding how the genes in mammals are controlled

New ways to enhance or block fertilization

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Human tissue grown from stem cells, available for transplant in the next four years

Gene B-myb essential in preventing tumors

Single molecular anchor holds the key to treating many types of bacterial meningitis

Parasite could help prevent asthma

Human embryonic stem cell lines accumulate changes in their genetic material over time

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

UK fertility specialist and broadcaster says embryonic stem cell research promises are hyped up

New understanding of how our genome works to produce a complex organism like a human being

Is the disease course of rheumatoid arthritis becoming milder?

New key evidence supports claims that some types of cancer originate with defects in stem cells

New drug will help fight against superbugs

Naturally occurring peptide hormones - candidates for the treatment of cancer, sexual dysfunction, eating disorders

Molecular switch that turns on the production of myelin

Potential new way to fight HIV

C. elegans worm provides clues to dealing with human disease

Researchers link individual preferences to neuronal activity in brain

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