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Researchers pinpoint circuit in the brain responsible for encoding decision-making

Researchers at The Johns Hopkins University have pinpointed a circuit in the brain responsible for encoding decision-making behavior, a circuit that - if damaged - appears to prevent a person from altering that behavior when circumstances change.

26 May 2005

'Brown fat cells' hold clues for possible obesity treatments

Joslin Diabetes Center scientists have discovered a group of genes that govern the genesis of calorie-burning fat cells. This discovery may lead to novel ways to treat obesity in humans.

26 May 2005

Protein, called "eed," crucial to the regulation of genes in embryonic stem cells

New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells.

26 May 2005

Study shows how COX-2 inhibitors lead to heart disease

University of Pennsylvania School of Medicine researchers have found additional evidence that may help explain how selective inhibitors of COX-2 might predispose individuals to heart disease and stroke.

26 May 2005

Breathing disorders during sleep are common among asthmatics

When asthmatics are awake, they can turn to their inhalers to open their airways. But when they sleep, many of them continue to struggle with breathing - and an understanding of their sleep-related problems may help doctors better diagnose and treat their patients' asthma, according to new University of Michigan Health System research.

26 May 2005

Scientists watch agents of brain-wasting diseases invade and move within brain cells

Scientists for the first time have watched agents of brain-wasting diseases, called transmissible spongiform encephalopathies (TSE), as they invade a nerve cell and then travel along wire-like circuits to points of contact with other cells.

25 May 2005

Ceramide can be administered through the blood stream to target and kill cancer cells

A Penn State College of Medicine study shows for the first time in an animal model that ceramide, a naturally occurring substance that prevents the growth of cells, can be administered through the blood stream to target and kill cancer cells.

25 May 2005

Team IDs mechanism for multiplying adult stem cells

While research on human embryonic stem cells gets most of the press, scientists are also investigating the potential therapeutic uses of adult stem cells. Although less controversial, this research faces other difficulties. Adult stem cells are extremely difficult to isolate and multiply in the lab.

24 May 2005

Researchers discover genetic trigger that plays a key role in cancer of the oesophagus

Cancer Research UK scientists at the University of Oxford have identified a gene which plays a key role in the development of cancer of the oesophagus by triggering changes in the oesophagus lining.

24 May 2005

Risks outweigh benefits of shark cartilage as anti-cancer treatment

As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance.

23 May 2005

Scientists show nuclear protein Ezh2 helps establish previously unknown signaling pathway in cells

Since 2001, scientists have wrestled with the discovery that there are fewer genes in humans than biological processes linked to those genes over the course of a human lifespan. One way to understand genetically coded events is by studying epigenetics, the regulation and heritability of genes at a cellular level due to molecular changes to the many proteins (called histones) that package DNA in a cell's nucleus.

23 May 2005

New product for advanced treatment of chronic wounds

Insense Ltd, a UK biotechnology company, announced successful clinical trial results for "Oxyzyme", a new product for advanced treatment of chronic wounds.

23 May 2005

Findings demonstrate that abnormal expression of the BCL6 gene causes lymphoma

This advancement has the potential to significantly speed the development of new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of non-Hodgkin’s lymphomas, the sixth leading cause of cancer deaths in the United States.

23 May 2005

LeTourneau University engineering students aid disabled Kenyans

Senior engineering students from LeTourneau University are leaving for Kijabe, Kenya, to fit disabled Kenyan children with free prosthetics.

23 May 2005

Russian team tests new polymeric coating for vascular stents

A group of researchers of the Institute of Biophysics (Russian Academy of Sciences), Krasnoyarsk regional clinical hospital and Krasnoyarsk regional department of morbid anatomy under the guidance of .I. Gitelzon, Academician of Russian Academy of Sciences, have tested characteristics of a new polymeric coating for vascular stents.

22 May 2005

WHO says world must prepare for bird flu pandemic

Reports of disturbing changes to the H5N1 virus circulating in Asia is causing great concern and has prompted the World Health Organization (WHO) to urge countries to prepare for a influenza pandemic.

22 May 2005

Discovery may lead to new drugs to treat cancer, control fertility

A recent discovery in cellular biology may allow scientists to enhance organ regeneration by stem cells, prevent the progression of cancer, and control fertility.

22 May 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

Study holds implications for gene therapy and stem cell biology

The study, conducted by scientists from Cincinnati Children's Hospital Medical Center, and Hannover Medical School and Hamburg University in Germany, reveals important evidence that tells us more about how blood forming stem cells regenerate. On the other hand, scientists offer caution in regards to the side effects associated with genetic engineering of stem cells.

20 May 2005