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Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Stem-cell breakthrough gives new hope for IVF treatments

In a scientific first, human eggs have been grown in the laboratory using stem cells scraped from the surface of women's ovaries and the development raises the possibility of delaying menopause and providing a limitless source of donor eggs for in vitro fertilisation treatments and embryonic stem cell research.

5 May 2005

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell.

5 May 2005

Drug safety in the doctor’s office - nearly half of patients have lapses in monitoring

According to research published in the Journal of General Internal Medicine, only slightly more than half of patients taking chronic medications received the recommended laboratory tests to monitor drug side effects.

5 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Cancer hijacks normal wound-healing processes

Scientists have known for the last decade that a link exists between wound healing and cancer. For instance, in a 1994 experiment at the Lawrence Berkeley National Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding.

5 May 2005

Pretty kids get the best deal all round

Disturbing new evidence from researchers at the University of Alberta in Canada, which is hard to believe, suggests that parents take better care of pretty children than they do of ugly ones.

4 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

Mutated gene causes serious heart disease in newborns

The research group of professor Manfred Kilimann at the Department of Cell and Molecular Biology has elucidated the genetic cause of a severe heart disease in newborn children. This result will be published in the June issue of the American Journal of Human Genetics this week.

3 May 2005

Scientists use tobacco plants to create antibodies against tumor cells

Scientists at Jefferson Medical College are using tobacco plants to produce monoclonal antibodies – tiny guided protein missiles – that can target and hunt down cancer cells. The plants promise to provide a cheaper, faster method of producing anticancer antibodies, raising hopes that the technology can one day be used in humans.

3 May 2005

Mother of all treatments could cure baldness, and banish stretch marks!

A new discovery by scientists might just be the 'mother of all treatments' in promising a treatment for balding men, women with stretchmarks and anyone who has gum disease.

3 May 2005

Vitamin C may help unborn of mothers who smoke

Thousands of babies born to mothers who continue to smoke throughout pregnancy despite physician warnings may benefit from new research which suggests that high doses of vitamin C may have the potential to counteract some negative impacts of smoking in unborn babies.

2 May 2005

Milk thistle not proven effective in lowering mortality in alcoholic or hepatitis B or C liver disease

While some studies found that liver-related mortality may be significantly reduced in patients treated with milk thistle, these findings were not duplicated in the higher quality clinical trials.

2 May 2005

Small number of genes can predict response to chronic hepatitis C therapy

For the first time, physicians at University Health Network and University of Toronto have identified a small subset of genes that can predict whether a patient with chronic Hepatitis C will be able to respond to current treatments.

2 May 2005

Fusing physics with medicine to fight cancer

Everyone’s lives are touched by cancer - it is a disease that affects 1 in 3 of us throughout our lifetime. Future developments that lead to earlier diagnosis and more effective therapy lie in further successful collaboration between high energy physicists and the healthcare industry.

2 May 2005

Laboratory News and Research

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Stem-cell breakthrough gives new hope for IVF treatments

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Drug safety in the doctor’s office - nearly half of patients have lapses in monitoring

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

Cancer hijacks normal wound-healing processes

Pretty kids get the best deal all round

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

Mutated gene causes serious heart disease in newborns

Scientists use tobacco plants to create antibodies against tumor cells

Mother of all treatments could cure baldness, and banish stretch marks!

Vitamin C may help unborn of mothers who smoke

Milk thistle not proven effective in lowering mortality in alcoholic or hepatitis B or C liver disease

Small number of genes can predict response to chronic hepatitis C therapy

Fusing physics with medicine to fight cancer

Defects in gene called RyR2 cause malfunctions in the heart's electrical system

Marburg virus - 275 confirmed cases

Vitamin C may have potential to counteract negative impacts of smoking in unborn babies

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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