Laboratory News and Research

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Researchers find way to produce cholesterol-lowering snack chips

Brandeis University biology professor K.C. Hayes and Senior Research Associate Andy Pronczuk at the school's Foster Biomedical Research Laboratory, and Senior Scientist Daniel Perlman in the Physics Department have discovered a way to produce chips and other snack foods that can actually lower your cholesterol while you eat them - without having any impact on taste

8 Feb 2005

Link between heart disease and periodontal bacteria

Researchers report this week that older adults who have higher proportions of four periodontal-disease-causing bacteria inhabiting their mouths also tend to have thicker carotid arteries, a strong predictor of stroke and heart attack.

7 Feb 2005

Nano-sized particles enable researchers to visualize a tumor using only infrared light

Nano-sized particles embedded with bright, light-emitting molecules have enabled researchers to visualize a tumor more than one centimeter below the skin surface using only infrared light.

7 Feb 2005

People with gum disease are more likely to suffer from atherosclerosis

A new study by researchers at Columbia University Medical Center provides the most direct evidence to date that preventing gum disease could significantly improve your chances of avoiding vascular problems.

7 Feb 2005

New way to assess the potentially damaging effects of prenatal drug exposure

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug exposure--a technique that could also be used to monitor a fetus's response to therapeutic drugs--using sophisticated, noninvasive medical imaging tools.

7 Feb 2005

Turning point in the history of preterm labor diagnosis

A combination of four proteins that result from inflammation and infection and lead to premature birth can be rapidly and accurately detected in the amniotic fluid of pregnant women using proteomics technology, Yale researchers report in two studies in the February issue of British Journal of Obstetrics and Gynecology.

7 Feb 2005

Gene used in brain development can cause childhood brain cancers

A gene that's normally silenced after contributing to brain development was found to be expressed in cells from medulloblastoma, the most common form of pediatric brain malignancy in children, scientists report in an article published in the February 1 issue of the journal Cancer Research.

3 Feb 2005

Male surgeons report highest rate of mistakes in patient care

Male surgeons report the highest rate of mistakes in patient care, reveals a study of doctors' attitudes to "adverse events" in Quality and Safety in Health Care.

3 Feb 2005

Compound, derived from a rare South American plant, stops the growth of human breast cancer cells

They started with a bare room and an idea. Now, after five years of painstaking, sophisticated tests, scientists at the University of Virginia Health System have discovered that a compound, derived from a rare South American plant, stops the growth of human breast cancer cells in laboratory cultures.

1 Feb 2005

Eleventh Edition of the Report on Carcinogens

The Department of Health and Human Services released its Eleventh Edition of the Report on Carcinogens today, adding seventeen substances to the growing list of cancer-causing agents, bringing the total to 246.

31 Jan 2005

Relationship between weight gain and breast cancer survival

Women who are overweight prior to breast cancer diagnosis, or who are lean but gain weight following diagnosis, are more likely to have their disease return or die of the disease, a new study shows. This effect was found to be particularly pronounced among women who had never smoked. The study is published online in the Journal of Clinical Oncology (JCO).

31 Jan 2005

Viagra protects cardiomyocytes against cell death

Virginia Commonwealth University researchers have shown that a widely used drug for treating erectile dysfunction, Viagra, reduces the death of heart cells under heart attack-like conditions in a laboratory model.

31 Jan 2005

Studying monkeys social judgments could provide clues to autism

Researches have found that monkeys will "pay" juice rewards to see images of high-ranking monkeys or female hindquarters. They say their research technique offers a rigorous laboratory approach to studying the "social machinery" of the brain and how this machinery goes tragically awry in autism -- a disease that afflicts more than a million Americans and is the fastest growing developmental disorder.

30 Jan 2005

Physical traits, genetic test help with early diagnosis of aneurysm syndrome

A research team led by Johns Hopkins doctors has defined the physical traits and genetic basis of a new aortic aneurysm syndrome that is extremely aggressive and can cause death in early childhood. Early diagnosis of the syndrome and rapid surgical repair of the swollen aorta can save lives, the researchers report in the Jan. 30 advance online section of Nature Genetics.

30 Jan 2005

One of the most exciting developments in clinical research in decades

One of the most exciting developments in clinical research in decades is taking place at the University of Leeds, led by our professor of cancer medicine Peter Selby in collaboration with the Medical Research Council.

27 Jan 2005

Avalanches in your brain could actually help you to store memories

Meeting a friend you haven't seen in years brings on a sudden surge of pleasant memories. You might even call it an avalanche.

26 Jan 2005

Calcium boost to youths' bones could reduce osteoporosis risk

New research on calcium and bone development suggests that efforts to prevent osteoporosis, generally considered a geriatric disease among women, could actually start before puberty.

26 Jan 2005

Scientists gain ground in understanding cell motility

One of the most basic yet least understood processes in our bodies is how cells crawl along tissues. This behavior is essential to the formation of an embryo and other processes, but it must be tightly controlled. A disturbance can lead to the spread of cancer cells or diseases like Spina bifida and Lissencephaly, in which cells fail to reach their proper destinations.

26 Jan 2005

Theory on evolution of essential genes is overturned

A gene passed on by fathers that plays a vital role in helping fertilised eggs to develop into adults has helped scientists overturn the idea that essential genes have always been part of the genetic makeup of a species.

26 Jan 2005

Researchers have uncovered evidence of sexual reproduction in a single-celled organism long thought to reproduce asexually

The finding by John M. Logsdon, Jr., assistant professor in the UI College of Liberal Arts and Sciences Department of Biological Sciences and the Roy J. Carver Center for Comparative Genomics, and colleagues from the UI and Roanoke College (Virginia), provides the first clear evidence that meiosis arose very early in eukaryotic evolution, bringing science one step closer to understanding the mystery of sexual evolution.

26 Jan 2005