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Melbourne researchers find link between necroptosis and inflammatory disease

A team of Melbourne researchers has shown a recently discovered type of cell death called necroptosis could be the underlying cause of inflammatory disease.

13 May 2014

Study: Calcium supplements may not increase risk of cardiovascular disease in women

Calcium supplements are widely taken by women for bone health. Previous studies have suggested that calcium supplements may increase risk of cardiovascular disease, but the data has been inconsistent.

12 May 2014

5-year survival of diabetic kidney transplant patients now on par with nondiabetic recipients

Mayo Clinic researchers have discovered that the five-year survival of diabetic kidney transplant patients is now on par with the five-year survival of nondiabetic kidney recipients.

9 May 2014

Comer Children's Hospital offers high-dose radiation therapy for relapsed neuroblastoma

The University of Chicago Medicine Comer Children's Hospital has become the first in Illinois to offer pioneering, targeted, high-dose, intravenous radiation therapy for relapsed neuroblastoma and other difficult-to-treat cancers.

9 May 2014

uEtG accurately detects alcohol consumption in liver transplant candidates and recipients

Researchers from Italy confirm that urinary ethyl glucuronide (uEtG) accurately detects alcohol consumption in liver transplant candidates and recipients.

9 May 2014

Hepatocellular carcinoma on the rise among Mexican Americans

Hepatocellular carcinoma (HCC), the primary cancer of the liver, is on the verge of becoming an epidemic among Mexican Americans, especially in Texas.

8 May 2014

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

Janssen Research & Development, LLC (Janssen) today announced it has submitted a Supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for simeprevir, an NS3/4A protease inhibitor marketed as OLYSIO™ in the United States, in combination with the nucleotide analog NS5B polymerase inhibitor sofosbuvir developed by Gilead Sciences, Inc.

8 May 2014

Triple therapy shows promise for severe PAH

Results of a small pilot study among patients with severe pulmonary arterial hypertension support the long-term benefits of upfront triple combination therapy, French researchers report.

7 May 2014

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

Ligand Pharmaceuticals Incorporated today reported financial results for the three months ended March 31, 2014, and provided an operating forecast and program updates.

7 May 2014

Perfusion system at room temperature preserves and improves metabolic function of donor livers

A system developed by investigators at the Massachusetts General Hospital (MGH) Center for Engineering in Medicine (CEM) and the MGH Transplant Center has the potential to increase both the supply and the quality of donor organs for liver transplantation.

7 May 2014

New model mimics structure of cornea to enable transplant of healthy corneal stem cells

Scientists have developed a model that mimics the complex structure of the cornea to enable the transplant of healthy corneal stem cells.

7 May 2014

Leading plastic surgeon invited to share latest advances in robotic hair restoration

Chicago plastic surgeon Gregory A. Turowski, MD, PhD, FACS, has been invited to be part of Harvard Medical School's "I Am Harvard," sharing his outcomes in the field of plastic surgery and advances in robotic hair restoration.

6 May 2014

Viewpoints: Battle for Medicaid; GOP's report on enrollment off base; need for kidney donations

The final battle of the war over the Affordable Care Act is being waged today over expanding Medicaid. ... The refusal of more than half the states to cover so many of their neediest citizens -; the number who have fallen into the "coverage gap" is estimated at 5 million -; amazes and frustrates health experts.

6 May 2014

FDA approves Alexion’s Soliris drug for treatment of atypical hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved the Company's supplemental Biologics License Application (sBLA) providing regular approval for Soliris® (eculizumab) for the treatment of adult and pediatric patients with atypical hemolytic uremic syndrome (aHUS) to inhibit complement-mediated thrombotic microangiopathy (TMA).

6 May 2014

Liver cancer screening in cirrhosis patients improves survival rates

Liver cancer survival rates could be improved if more people with cirrhosis are screened for tumors using inexpensive ultrasound scans and blood tests, according to a review by doctors at UT Southwestern Medical Center.

6 May 2014

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

A surprise discovery that could lead to new treatments for herpes viruses that infect more than 90 percent of the world's adult population has led to a $1.8 million grant to the University of Arkansas for Medical Sciences (UAMS) from the National Cancer Institute (NCI) at the National Institutes of Health (NIH).

5 May 2014

New findings show combination of statins and omega-3 fatty acid may potentially reduce cardiovascular risk

New findings from an in vitro study, led by researchers at Brigham and Women's Hospital (BWH), show that the combination of statins and eicosapentaenoic acid (EPA), an omega-3 fatty acid, may potentially reduce cardiovascular risk.

2 May 2014

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Second Genome announced today that it has entered into an agreement with Pfizer Inc. to conduct extensive microbiome research in a large observational study aimed at gaining new insights into obesity and metabolic disease.

2 May 2014

Cedars-Sinai director honored for lifetime of achievement in field of liver transplantation

Andrew S. Klein MD, MBA, director of the Cedars-Sinai Comprehensive Transplant Center is being honored for a lifetime of achievement in the field of liver transplantation by the Los Angeles chapter of the American Liver Foundation.

2 May 2014

Sleep habits associated with memory in old-age

A new research study led by Brigham and Women's Hospital (BWH) published in The Journal of the American Geriatrics Society in May, shows an association between midlife and later life sleeping habits with memory; and links extreme sleep durations to worse memory in later life. The study suggests that extreme changes in sleep duration from middle age to older age may also worsen memory function.

1 May 2014

Transplant News and Research

Melbourne researchers find link between necroptosis and inflammatory disease

Study: Calcium supplements may not increase risk of cardiovascular disease in women

5-year survival of diabetic kidney transplant patients now on par with nondiabetic recipients

Comer Children's Hospital offers high-dose radiation therapy for relapsed neuroblastoma

uEtG accurately detects alcohol consumption in liver transplant candidates and recipients

Hepatocellular carcinoma on the rise among Mexican Americans

Janssen submits sNDA to FDA for simeprevir in combination with sofosbuvir for treatment of HCV genotype 1 infection

Triple therapy shows promise for severe PAH

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

Perfusion system at room temperature preserves and improves metabolic function of donor livers

New model mimics structure of cornea to enable transplant of healthy corneal stem cells

Leading plastic surgeon invited to share latest advances in robotic hair restoration

Viewpoints: Battle for Medicaid; GOP's report on enrollment off base; need for kidney donations

FDA approves Alexion’s Soliris drug for treatment of atypical hemolytic uremic syndrome

Liver cancer screening in cirrhosis patients improves survival rates

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

New findings show combination of statins and omega-3 fatty acid may potentially reduce cardiovascular risk

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Cedars-Sinai director honored for lifetime of achievement in field of liver transplantation

Sleep habits associated with memory in old-age

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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