Embryonic Stem Cells News and Research

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Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Stem cells that have been specifically developed for use as clinical therapies are fit for use in patients, an independent study of their genetic make-up suggests.

26 Nov 2015

Microgravity inhibits regenerative and differentiation potential of embryonic stem cells

A study performed on the NASA Space Shuttle Discovery showed that exposure of mouse embryonic stem cells (mESCs) to microgravity inhibited their ability to differentiate and generate most cell lineages, needed for the development of bone, muscle, the immune system, and other organs and tissues.

24 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

Researchers identify factors that spark formation of pluripotent cells

Researchers at EMBL's European Bioinformatics Institute and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells.

10 Nov 2015

Public policy needed to reduce stem cell tourism, say experts

The continued marketing and use of experimental stem cell-based interventions inside and outside the United States is problematic and unsustainable, according to a new paper by science policy and bioethics experts at Rice University's Baker Institute for Public Policy and Wake Forest University.

10 Nov 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Alzheimer's disease (AD), affecting millions worldwide, is the leading cause of dementia. The prevalence of AD is rapidly increasing, and will possibly affect over 100 million people by 2050, yet there are no effective therapies for the disease.

31 Oct 2015

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

The New York Stem Cell Foundation announced today that Franziska Michor, PhD, is the 2015 recipient of the NYSCF - Robertson Stem Cell Prize for her work pioneering new approaches to study the growth, spread, and treatment of cancer. Her laboratory fuses her passions in mathematics, molecular biology and patient care to investigate how cancers form and progress.

29 Oct 2015

Researchers successfully convert skin cells into fully functional placenta-generating cells

Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs in the human body through cellular transplantation. Embryonic stem cells (ESCs) are pluripotent cells that are capable of long-term growth, self-renewal, and can give rise to every cell, tissue and organ in the fetus's body.

15 Oct 2015

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

An international study led by researchers from IMIM (Hospital del Mar Medical Research Institute) published in the journal Nature Communications has revealed that the intensity or efficiency of the activation of a protein called Notch, which is involved in the different phases of embryonic development, determines the fate of cells, i.e. if cells will form the aorta artery or blood (hematopoietic) stem cells. For artery cells, many Notch molecules need to be activated, whereas for hematopoietic cells many fewer are needed.

14 Oct 2015

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

A sticky, protein-rich gel created by Johns Hopkins researchers appears to help stem cells stay on or in rat hearts and restore their metabolism after transplantation, improving cardiac function after simulated heart attacks, according to results of a new study.

25 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Simple stem cell production method shows promise in mice for treating IPF

In a small pilot study, researchers from North Carolina State University have demonstrated a rapid, simple way to generate large numbers of lung stem cells for use in disease treatment. This method of harvesting and growing a patient's own lung stem cells shows promise in mice for treating idiopathic pulmonary fibrosis (IPF), and could one day provide human IPF sufferers with an effective, less invasive method of treatment for their disease.

10 Sep 2015

Mel18 protein regulates development of heart muscle

It is arguably the hardest working muscle in our body and without its incessant, regular beating our organs would be starved of life-giving nutrients.

4 Sep 2015

Gene ZSCAN4 may help treat Down syndrome

For people with Down syndrome, news from Elixirgen, LLC may brighten their day. The biotechnology company, located in the Science + Technology Park at Johns Hopkins, has outlined one of the best potential therapies yet for people with Down syndrome and other chromosome disorders in a paper entitled, "Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures," published in the journal DNA Research.

31 Aug 2015

Embryonic Stem Cells News and Research

Research paves way for clinical trials of cell therapies to treat Parkinson's disease, spinal cord injury

Microgravity inhibits regenerative and differentiation potential of embryonic stem cells

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Researchers identify factors that spark formation of pluripotent cells

Public policy needed to reduce stem cell tourism, say experts

Key protein controls stem cell properties that could make them useful in regenerative medicine

Prkci gene maintains balance in stem cell production

Stem cell transplantation may offer viable treatment for Alzheimer's disease patients

Franziska Michor named recipient of NYSCF - Robertson Stem Cell Prize

Researchers successfully convert skin cells into fully functional placenta-generating cells

Notch activation determines signals necessary to generate hematopoietic stem cells in laboratory

Sticky, protein-rich gel improves cardiac function after simulated heart attacks

Scientists uncover how embryonic stem cells inhibit virus expression

Simple stem cell production method shows promise in mice for treating IPF

Mel18 protein regulates development of heart muscle

Gene ZSCAN4 may help treat Down syndrome

UCSF study reveals molecular timing mechanism of stem cells

Elsevier launches open access journal Reproductive Biomedicine & Society Online

Rush researchers explore new stem cell therapy to treat spinal cord injuries

FGF protein may play key role in breast and prostate cancer, shows research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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