Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Agendia and Angsana partner to market MammaPrint, BluePrint breast cancer tests in Southeast Asia

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, and Angsana Molecular & Diagnostics Laboratory Pte Ltd, a subsidiary of Parkway Pantai, announce a partnership to market the MammaPrint Breast Cancer Risk of Recurrence test and the BluePrint Molecular Subtyping test to physicians across Southeast Asia, including Singapore, Malaysia, Vietnam, Brunei and Myanmar.

31 May 2018

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

An analysis of lymph node dissection in renal cell carcinoma that has not spread to other organs indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit.

21 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

According to a new study, the status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive.

2 May 2018

Direct contact with lymphatic endothelial cells promotes melanoma metastasis

Despite the declining death rates for many individual cancer types, mortality for a few cancers has stabilized or even increased. One of these is melanoma due to its ability, in later stages, to spread to other parts of the body.

2 May 2018

Novel magnetic nanoparticles move from lab to first breast cancer clinical trials

Sandia National Laboratories materials chemist Dale Huber has been working on the challenge of making iron-based nanoparticles the exact same size for 15 years.

30 Apr 2018

Axillary ultrasound imaging found to be inferior for detecting lymph node metastases in breast cancer

For patients diagnosed with breast cancer, determining whether cancer cells have spread to the axillary lymph nodes of the armpit is important for guiding treatment decisions. It has been debated whether axillary ultrasound imaging is equally sensitive for detecting axillary metastatic lymph nodes in different subtypes of breast cancer.

17 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Mice study reveals important role of pTreg cell population in autoimmune diabetes

In autoimmune diseases such as type 1 diabetes, some of the immune system's T cells mistakenly attack the body's own cells, while protective T regulatory cells try to defend against that attack.

6 Apr 2018

Researchers discover Tfh cell dysfunction in HIV-infected patients

A team of chemical and biomedical engineers from the Cockrell School of Engineering at The University of Texas at Austin, in collaboration with researchers from the University of Pennsylvania, have discovered that HIV-infected patients experience a dysfunction in a certain type of immune cell: the follicular helper T (Tfh) cell.

6 Apr 2018

Research finds breast lesions in transmen undergoing mastectomy

The number of transmen seeking gender-confirming surgery has risen in the past decade. In a paper published in the British Journal of Surgery analyzing breast tissue from 344 transmen undergoing mastectomy, breast lesions--either benign or malignant--were present in 166 individuals (48.3%).

5 Apr 2018

Sentinel lymph node biopsies could be safely avoided for some breast cancer patients

Sentinel lymph node biopsies, where lymph nodes are surgically removed to check for signs of breast cancer spread, could be safely avoided for some women, according to research presented at the 11th European Breast Cancer Conference.

21 Mar 2018

Discovery opens new doors to developing vaccines for preventing staph skin infections

After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph).

6 Feb 2018

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Men with type 2 diabetes are less likely to develop prostate cancer than patients without diabetes. However, the mortality rate is higher.

31 Jan 2018

UAMS Myeloma Institute expert compiles new book on Castleman disease

Castleman disease, a rare disorder of the lymph nodes and related tissues, was identified and named more than a half-century ago but, until recently, no one had written a book exclusively about it.

30 Jan 2018

YCC researchers propose new patient selection methods for breast cancer clinical trials

Many clinical trials for breast cancer fail to give clear answers on the efficacy of new therapies, despite enrolling thousands of patients and painstakingly tracking their outcomes for years.

25 Jan 2018

New way to identify breast cancer patients who may develop incurable secondary tumors

Scientists from King's College London, funded by Breast Cancer Now, believe they have found a way to identify lymph-node positive breast cancer patients who are most likely to develop incurable secondary tumours (metastases) and those who are less at risk.

9 Jan 2018

Study reveals a loophole in treatment of chronic lymphocytic leukemia

A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients.

4 Jan 2018

Study indicates decline in use of chemotherapy for early stage breast cancer patients

A study of nearly 3,000 women with early stage breast cancer indicates a recent, significant decline in the use of chemotherapy despite the lack of any change in national treatment recommendations or guidelines, according to researchers at the Stanford University School of Medicine and the University of Michigan.

11 Dec 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017