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Using AI might afford large-scale evaluation for splenomegaly on CT examinations

According to an accepted manuscript published in ARRS' own American Journal of Roentgenology (AJR), using an automated deep-learning AI tool, as well as weight-based volumetric thresholds, might afford large-scale evaluation for splenomegaly on CT examinations performed for any indication.

3 Jul 2023

Experimental antibody treatment shows promise for preventing bone marrow transplant complication

An experimental antibody treatment largely prevented a bone marrow transplant complication called graft versus host disease (GVHD) in the intestines, without causing broad immune suppression, in a preclinical study led by researchers from Penn Medicine and Dana-Farber/Boston Children's Cancer and Blood Disorders Center and published today in Science Translational Medicine.

28 Jun 2023

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.

28 Jun 2023

Measurable upticks in gut bacteria blooms tied to lupus flare-ups

Recurrent bouts of systemic lupus erythematosus, marked by the body's immune system attack of its own tissues, closely tracked with measurable upticks in growth in the gut of a certain species of bacteria.

27 Jun 2023

Study sheds new light on the relationship between gut microbiome and autism

The biological roots of autism continue to perplex researchers, despite a growing body of studies looking at an increasing array of genetic, cellular and microbial data.

26 Jun 2023

Experts call on leading institutions to review support for disgraced transplant surgeon

It's time for some of the world's best hospitals and research institutes to launch full and independent investigations into their support for disgraced transplant surgeon Paolo Macchiarini, argue experts in The BMJ today. Responses from those concerned are also published.

22 Jun 2023

New standard more effective at preventing graft-versus-host disease

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal of Medicine.

22 Jun 2023

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

The University of Texas MD Anderson Cancer Center and New Orleans-based Ochsner Health today announced a partnership to create Ochsner MD Anderson Cancer Center in southeastern Louisiana.

22 Jun 2023

Newborn screening for "bubble-baby" disease boosts survival of children

Screening newborns for severe combined immunodeficiency disease (SCID) significantly increases the survival of children after bone marrow transplantation, a new North American study finds.

21 Jun 2023

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

A single mutation stands in the way of a drug's effectiveness. Understanding it helps find new therapeutic approaches.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

Unlocking HIV cure: Study highlights allogeneic immunity as key mechanism in eradicating latent virus reservoirs

Allogeneic stem cell transplantation with CCR5Δ32/Δ32 donors shows potential for HIV cure. Alloimmunity and CCR5 deficiency play significant roles in viral reservoir clearance.

19 Jun 2023

Unlocking the secret to lifelong health: the power of optimal immune resilience

Researchers assessed immune resilience (IR) metrics in individuals across diverse infectious and non-infectious models.

15 Jun 2023

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

15 Jun 2023

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

A study led by researchers at the Garvan Institute of Medical Research shows for the first time how a gene called RELA, known to regulate inflammation, also plays an essential role in maintaining normal blood-sugar levels.

14 Jun 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023

Immune resilience promotes longevity and resistance to infections

Researchers from The University of Texas Health Science Center at San Antonio, working with collaborators in five countries, today revealed that the capacity to resist or recover from infections and other sources of inflammatory stress -; called "immune resilience" -; differs widely among individuals.

13 Jun 2023

Researchers develop protein biomarker panels to predict developmental dysplasia of the hip

Researchers from the University of Missouri School of Medicine have developed panels of protein biomarkers present in teens and young adults that distinguish individuals with healthy hips from those with developmental dysplasia of the hip, also known as hip dysplasia, which often progresses to hip osteoarthritis if not recognized before early adulthood.

13 Jun 2023

Vitamin D deficiency during pregnancy linked to an increased risk of Type 2 diabetes in offspring

Researchers at Washington University School of Medicine in St. Louis have identified a process in immune cells that links vitamin D deficiency during pregnancy to an increased risk of Type 2 diabetes in offspring.

13 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Transplant News and Research

Using AI might afford large-scale evaluation for splenomegaly on CT examinations

Experimental antibody treatment shows promise for preventing bone marrow transplant complication

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

Measurable upticks in gut bacteria blooms tied to lupus flare-ups

Study sheds new light on the relationship between gut microbiome and autism

Experts call on leading institutions to review support for disgraced transplant surgeon

New standard more effective at preventing graft-versus-host disease

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

Newborn screening for "bubble-baby" disease boosts survival of children

Single mutation of the hepatitis E virus stands in the way of sofosbuvir drug's effectiveness

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Unlocking HIV cure: Study highlights allogeneic immunity as key mechanism in eradicating latent virus reservoirs

Unlocking the secret to lifelong health: the power of optimal immune resilience

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

Understanding the developmental link: vitamin D's role in metabolic disease risk

Immune resilience promotes longevity and resistance to infections

Researchers develop protein biomarker panels to predict developmental dysplasia of the hip

Vitamin D deficiency during pregnancy linked to an increased risk of Type 2 diabetes in offspring

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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