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Review: Stem cell therapy for chronic ischaemic heart disease

Stem cell therapies work as a complement to standard treatments, potentially cutting the number of deaths after a year, suggests evidence from the latest Cochrane review: Stem cell therapy for chronic ischaemic heart disease and congestive heart failure.

30 Apr 2014

Studies provide insight on quality of kidney and liver transplantation

The quality of kidney and liver donations is fundamentally important for the longevity of transplants and the health of recipients. That’s why it’s critical to know which organs are suitable for transplantation, as well as to use techniques that preserve an organ’s function after donation.

29 Apr 2014

Cell Therapeutics announces launch of PIXUVRI in the UK for treatment of aggressive B-cell NHL

Cell Therapeutics, Inc. today announced the launch of PIXUVRI (pixantrone), the first new treatment for adult patients in the United Kingdom (UK) with multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphoma (aggressive B-cell NHL), at the 54th annual scientific meeting of the British Society for Haematology.

29 Apr 2014

Researchers develop art-based program to help prevent heart disease

For patients with end stage heart disease who need a heart transplant, the experience of an extended hospitalization while waiting for a life-saving organ and then undergoing life-saving surgery can be an emotional and stressful journey.

28 Apr 2014

Junk DNA linked to heart failure, reveals Washington University study

Large sections of the genome that were once referred to as "junk" DNA have been linked to human heart failure, according to research from Washington University School of Medicine in St. Louis.

26 Apr 2014

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

Concert Pharmaceuticals, Inc. today announced 48-week results of its Phase 2 clinical trial of CTP-499 in patients with diabetic kidney disease. CTP-499, when used in addition to the standard of care, is being developed to delay the progression of these patients to end-stage renal failure, which requires dialysis or kidney transplantation.

26 Apr 2014

Use of frozen stool for fecal transplant successfully treats C. difficile infection

Using frozen stool from healthy, unrelated donors was safe and effective in treating patients with serious, relapsing diarrhea caused by Clostridium difficile, according to a new pilot study published in Clinical Infectious Diseases and available online.

25 Apr 2014

Study offers evidence supporting use of autologous stem cell-based treatment for stroke

People who have had a stroke, often suffer motor deficits with little potential to restore neurological function.

25 Apr 2014

Captisol-enabled Melphalan meets primary end points in phase 2 pivotal trial

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in Hematology and Oncology, today announced that its pivotal trial of Captisol-enabled (propylene glycol-free) Melphalan met its primary end points.

23 Apr 2014

Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

Alexion Pharmaceuticals, Inc. today announced that the European Commission has granted an orphan drug designation (ODD) to Soliris (eculizumab), a first-in-class terminal complement inhibitor, for the prevention of graft rejection following solid organ transplantation. Graft rejection can cause severe injury to the transplanted organ and is a significant barrier to successful transplantation.

23 Apr 2014

VHVI implants miniaturized HeartWare HVAD Pump through minimally invasive approach

Sometimes smaller is better. This is especially true of left ventricular assist devices, the mechanically operated heart pumps that are implanted in heart failure patients to bridge them to transplantation.

23 Apr 2014

Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer Inc. announced today top-line results from two pivotal Phase 3 trials from the Oral treatment Psoriasis Trials (OPT) Program, OPT Pivotal #1 (A3921078) and OPT Pivotal #2 (A3921079), evaluating the efficacy and safety of tofacitinib, an oral Janus kinase (JAK) inhibitor, the first in a new class of medicines being investigated for the treatment of moderate-to-severe plaque psoriasis.

23 Apr 2014

Stool color guide and free mobile app help diagnose liver-ravaging disorder in babies

Fecal color and consistency are well-known markers of digestive health in both children and adults, but paying attention to a newborn's shade of poop can be a decided lifesaver in babies born with the rare, liver-ravaging disorder biliary atresia, commonly heralded by white or clay-colored stool.

22 Apr 2014

Study suggests that improving newborns' bacterial environment could fend off infections

Mothers give a newborn baby a gift of germs-germs that help to kick-start the infant's immune system. But antibiotics, used to fend off infection, may paradoxically interrupt a newborn's own immune responses, leaving already-vulnerable premature babies more susceptible to dangerous pathogens.

21 Apr 2014

Le Bonheur Children's takes aggressive steps to minimize blood loss during heart surgery

More than 20 percent of Le Bonheur Children's Hospital's open heart surgeries are now bloodless, meaning no blood or blood products given during surgery. The Memphis, Tenn., hospital's Heart Institute has been taking aggressive steps to minimize blood loss during surgery and reduce perioperative blood transfusions over the last 18 months.

18 Apr 2014

Docs who treat patients with severe LAM face agonizing treatment decision

Doctors who treat patients with a severe and progressive respiratory disease called lymphangioleiomyomatosis (LAM) can face an agonizing treatment decision.

18 Apr 2014

New parents need to pay attention to baby’s poop color, say pediatric gastroenterologists

Fecal color and consistency are well-known markers of digestive health in both children and adults, but paying attention to a newborn’s shade of poop can be a decided lifesaver in babies born with the rare, liver-ravaging disorder biliary atresia, commonly heralded by white or clay-colored stool.

18 Apr 2014

iGetBetter joins Massachusetts Hospital Association to reduce hospital readmissions

iGetBetter, a supplier of post-acute care transition solutions designed to help reduce hospital readmissions, and the Massachusetts Hospital Association (MHA), the primary representative of the hospital community in the commonwealth, announced today that iGetBetter will join MHA and contribute to efforts now underway by Massachusetts hospitals to improve post-discharge care transition and reduce hospital readmissions.

17 Apr 2014

MD Anderson honors America's future cancer leaders

The University of Texas MD Anderson Cancer Center this week honored 16 junior faculty members who are expected to become some of America's future cancer leaders. The faculty members are the first R. Lee Clark Fellow award winners. The new award was established to recognize outstanding work by junior faculty members and to help support their future efforts.

16 Apr 2014

Harvard successfully transplants regenerated esophagus into rat using bioreactor

Harvard Apparatus Regenerative Technology, Inc., a clinical stage biotechnology company developing regenerated organs for transplant, initially focused on the trachea, announces that a research team led by Paolo Macchiarini, MD, PhD at Karolinska Institutet in Sweden has successfully transplanted a regenerated esophagus into a rat using a bioreactor developed by HART.

16 Apr 2014

Transplant News and Research

Review: Stem cell therapy for chronic ischaemic heart disease

Studies provide insight on quality of kidney and liver transplantation

Cell Therapeutics announces launch of PIXUVRI in the UK for treatment of aggressive B-cell NHL

Researchers develop art-based program to help prevent heart disease

Junk DNA linked to heart failure, reveals Washington University study

Concert Pharmaceuticals reports results from CTP-499 Phase 2 trial in patients with diabetic kidney disease

Use of frozen stool for fecal transplant successfully treats C. difficile infection

Study offers evidence supporting use of autologous stem cell-based treatment for stroke

Captisol-enabled Melphalan meets primary end points in phase 2 pivotal trial

Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

VHVI implants miniaturized HeartWare HVAD Pump through minimally invasive approach

Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Stool color guide and free mobile app help diagnose liver-ravaging disorder in babies

Study suggests that improving newborns' bacterial environment could fend off infections

Le Bonheur Children's takes aggressive steps to minimize blood loss during heart surgery

Docs who treat patients with severe LAM face agonizing treatment decision

New parents need to pay attention to baby’s poop color, say pediatric gastroenterologists

iGetBetter joins Massachusetts Hospital Association to reduce hospital readmissions

MD Anderson honors America's future cancer leaders

Harvard successfully transplants regenerated esophagus into rat using bioreactor

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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