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Approved dengue vaccine may increase infection in certain settings, research suggests

The only approved vaccine for dengue may actually increase the incidence of dengue infections requiring hospitalization rather than preventing the disease if health officials aren't careful about where they vaccinate, new public health research published Sept. 2 in Science suggests.

1 Sep 2016

Foul smelling gas could help people with diabetes recover from heart complications

A gas that was formerly known for its noxious qualities could help people with diabetes recover from common heart and blood vessel complications, concludes research led by the University of Exeter Medical School.

1 Sep 2016

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.

31 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

In a study focusing on the role of self-donated (autologous) bone marrow-derived endothelial progenitor cells (EPCs) in placental vascular development, researchers in Japan have discovered that when transplanted into pregnant mice, EPCs can contribute to better blood vessel growth that helps in forming "normalized" placental vascularization, leading, in turn, to reduced recurrent miscarriages by providing a healthier fetal environment during gestation.

30 Aug 2016

New research finds decrease in brain blood flow after stopping exercise in healthy older adults

We all know that we can quickly lose cardiovascular endurance if we stop exercising for a few weeks, but what impact does the cessation of exercise have on our brains? New research led by University of Maryland School of Public Health researchers examined cerebral blood flow in healthy, physically fit older adults (ages 50-80 years) before and after a 10-day period during which they stopped all exercise.

29 Aug 2016

Paleo diet may be beneficial for heart health

The popular Paleo diet is based on eating foods thought to be available to our ancestors during the Paleolithic era, before the advent of dairy or processed grains.

26 Aug 2016

New drug delivery system slows and controls tumors not aiming for complete elimination

Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.

26 Aug 2016

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis.

26 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

New research discovers how opposite-sex hormonal therapy influences the brain

Women and men often show marked differences as regards mental illnesses. In order to learn more about this phenomenon, a project supported by the Austrian Science Fund FWF explored how opposite-sex hormonal therapy applied to transgender individuals influences the brain.

24 Aug 2016

Researcher aims to shed new light on inner workings of the retina

One of the more studied parts of the human anatomy, the retina -- the neural layer at the back of the eye that senses light -- still has secrets to reveal.

23 Aug 2016

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers.

23 Aug 2016

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive.

23 Aug 2016

Tel Aviv University researchers unravel how melanoma spreads to distant organs

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers.

23 Aug 2016

Morbidly obese individuals more likely to experience heart failure, say researchers

A study by Johns Hopkins researchers of more than 13,000 people has found that even after accounting for such risk factors as high blood pressure, high cholesterol and diabetes, so-called morbid obesity appears to stand alone as a standout risk for heart failure, but not for other major types of heart disease.

22 Aug 2016

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours.

19 Aug 2016

Colorectal tumors present epigenetic heterogeneity, study finds

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease.

18 Aug 2016

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer.

18 Aug 2016

Novel material heals diabetic wounds faster than standard bandage

At some point in their lives, 15 percent of people with diabetes will develop a painful and hard-to-treat foot ulcer.

18 Aug 2016

Blood Vessels News and Research

Approved dengue vaccine may increase infection in certain settings, research suggests

Foul smelling gas could help people with diabetes recover from heart complications

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

Study suggests autologous EPC transfusion may prevent miscarriage in high-risk pregnancies

New research finds decrease in brain blood flow after stopping exercise in healthy older adults

Paleo diet may be beneficial for heart health

New drug delivery system slows and controls tumors not aiming for complete elimination

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

New research discovers how opposite-sex hormonal therapy influences the brain

Researcher aims to shed new light on inner workings of the retina

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

NIH researchers discover rare, lethal inflammatory disease that affects young children

Tel Aviv University researchers unravel how melanoma spreads to distant organs

Morbidly obese individuals more likely to experience heart failure, say researchers

Added benefit not proven for orphan drug in treatment of adults with stomach cancer

Colorectal tumors present epigenetic heterogeneity, study finds

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

Novel material heals diabetic wounds faster than standard bandage

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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