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Omeros submits investigational new drug to initiate OMS721 Phase 2 clinical program

Omeros Corporation today announced that it has submitted to the U.S. Food and Drug Administration (FDA) an investigational new drug (IND) application to initiate the Phase 2 clinical program for OMS721, the company's lead human monoclonal antibody targeting mannan-binding lectin‑associated serine protease-2 (MASP-2), the key regulator of the lectin pathway of the immune system.

4 Mar 2014

AJT describes novel approach to long-term tolerance in organ transplantation

REGiMMUNE Corporation announced that the American Journal of Transplantation (AJT) has published its paper that describes a novel approach to long-term tolerance in organ transplantation with continuous administration of immune suppressants.

4 Mar 2014

Research discovery advances efforts to replace damaged heart muscle

In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.

4 Mar 2014

Researcher to receive AACR- Joseph H. Burchenal Memorial Award for achievement in cancer research

John F. DiPersio, M.D., Ph.D., will be recognized with the 19th Annual American Association for Cancer Research-Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research at the AACR Annual Meeting 2014, to be held in San Diego, Calif., April 5-9.

3 Mar 2014

Transplanting lungs from heavy smoking donors does not appear to negatively affect recipient outcomes

Transplanting lungs from donors with a history of heavy smoking does not appear to negatively affect recipient outcomes following surgery, according to a study in the March 2014 issue of The Annals of Thoracic Surgery.

28 Feb 2014

Dampening immune response may encourage lung transplant rejection

Organ transplant patients routinely receive drugs that stop their immune systems from attacking newly implanted hearts, livers, kidneys or lungs, which the body sees as foreign.

27 Feb 2014

Organ recovery centers could improve efficiency, reduce costs associated with deceased organ donation

Free-standing organ recovery centers could markedly improve efficiency and reduce costs associated with deceased organ donation, according to a new study published in the American Journal of Transplantation.

27 Feb 2014

Report calls for better palliative and EOL care for patients that relapse following transplant

Haematological disorders of the blood and bone marrow, such as leukaemia, are commonly treated with a bone marrow transplant. However relapse is common and often leads to treatment failure and death.

26 Feb 2014

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Protein M is a cell surface protein from Mycoplasma Genitalium that binds to all human antibodies.

26 Feb 2014

Fred Hutchinson, SCCA researchers receive Seattle Business Magazine's 2014 Leaders in Health Care Awards

Researchers at Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance (SCCA) were recognized in several categories of Seattle Business Magazine's 2014 Leaders in Health Care Awards, including the publication's Lifetime Achievement Award, given to Frederick R. Appelbaum, M.D., executive vice president and deputy director of Fred Hutch and president of SCCA.

26 Feb 2014

FamilyCord provides direct cord blood and cord tissue services to Venezuelan families

FamilyCord, a subsidiary of California Cryobank, now provides direct cord blood and cord tissue services to Venezuelan families and has assumed management of clients of Cordon de Vida, one of Venezuela's largest cord blood banks.

25 Feb 2014

Moving organ donors to stand-alone facility for retrieving organs is more efficient, lowers costs

Retrieving organs from brain-dead donors is logistically challenging and time consuming in hospitals. Multiple surgical teams often fly to a donor's hospital but frequently face delays in retrieving organs due to crowded operating-room schedules.

25 Feb 2014

New class of drugs developed to treat cancer, reduces sudden cardiac death risk after heart attack

A researcher at the Cardiovascular Institute (CVI) at Rhode Island, The Miriam and Newport hospitals has found that a new class of drugs, originally developed to treat cancer, reduces sudden cardiac death risk after a heart attack. The findings were published online in advance of print in the Journal of the American College of Cardiology.

25 Feb 2014

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) to update the current label of XELJANZ® (tofacitinib citrate) 5 mg tablets to include radiographic data from two Phase 3 studies, ORAL Scan (A3921044) and ORAL Start.

25 Feb 2014

Study highlights novel reprogramming method that offers new hope for treating liver failure

The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature-a crucial prerequisite for life-saving therapies-has proven far more difficult.

24 Feb 2014

Cell therapy: A powerful treatment for cancer patients

Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted to date of patients with advanced leukemia found that 88 percent achieved complete remissions after being treated with genetically modified versions of their own immune cells.

24 Feb 2014

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

A new UCLA-led study shows that a blood test commonly used to determine whether heart transplant recipients are rejecting their new organ can also predict potential rejection-related problems in the future.

19 Feb 2014

Study shows how immune system reconstitutes itself following immune-depleting therapy

A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes.

18 Feb 2014

Dua's Layer in the human cornea may be linked to glaucoma

A new layer in the human cornea - discovered by researchers at The University of Nottingham last year - plays a vital role in the structure of the tissue that controls the flow of fluid from the eye, research has shown.

17 Feb 2014

TPI announces financial results for second quarter fiscal year 2014

Tianyin Pharmaceutical Inc., a pharmaceutical company that specializes in the patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), branded generics and active pharmaceutical ingredients (API) announced financial results for the second quarter fiscal year 2014.

14 Feb 2014

Transplant News and Research

Omeros submits investigational new drug to initiate OMS721 Phase 2 clinical program

AJT describes novel approach to long-term tolerance in organ transplantation

Research discovery advances efforts to replace damaged heart muscle

Researcher to receive AACR- Joseph H. Burchenal Memorial Award for achievement in cancer research

Transplanting lungs from heavy smoking donors does not appear to negatively affect recipient outcomes

Dampening immune response may encourage lung transplant rejection

Organ recovery centers could improve efficiency, reduce costs associated with deceased organ donation

Report calls for better palliative and EOL care for patients that relapse following transplant

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Fred Hutchinson, SCCA researchers receive Seattle Business Magazine's 2014 Leaders in Health Care Awards

FamilyCord provides direct cord blood and cord tissue services to Venezuelan families

Moving organ donors to stand-alone facility for retrieving organs is more efficient, lowers costs

New class of drugs developed to treat cancer, reduces sudden cardiac death risk after heart attack

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Study highlights novel reprogramming method that offers new hope for treating liver failure

Cell therapy: A powerful treatment for cancer patients

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

Study shows how immune system reconstitutes itself following immune-depleting therapy

Dua's Layer in the human cornea may be linked to glaucoma

TPI announces financial results for second quarter fiscal year 2014

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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