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4SC initiates dosing in resminostat Phase I/II SHORE study for KRAS-mutant colorectal cancer

4SC AG, a drug discovery and development company, today announced that the first patient has been dosed in the Phase I/II SHORE study with the oral pan-histone deacetylase (HDAC) inhibitor resminostat as a second-line treatment for patients with advanced and metastatic colorectal KRAS-mutant cancer.

20 Jan 2011

Data on Ensituximab for treatment of pancreatic and colorectal cancers to be presented at ASCO 2011

Neogenix Oncology announced today that Dr. Luis Diaz of The Johns Hopkins University Hospital will present data from Ensituximab, the company's novel, therapeutic antibody to treat pancreatic and colorectal cancers. The presentation is scheduled at the American Society of Clinical Oncology (ASCO) 2011 Gastrointestinal Cancers Symposium to be held January 20-22, 2011 at the Moscone Center in San Francisco, CA, USA.

19 Jan 2011

Health care reform should mend disconnect between USPSTF recommendations and Medicare coverage

Health care reform should be able to mend a disconnect that has existed between the recommendations of the U.S. Preventive Services Task Force (USPSTF), a task force charged by the government to review clinical preventive health services for older adults, and Medicare coverage for those services, a new UCLA-led study finds.

19 Jan 2011

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

The Scripps Research Institute has been awarded $3.17 million over four years to develop compounds that will counteract disruptions of the human biological clock - the circadian rhythm that regulates our patterns of activity and rest over a 24-hour daily cycle.

19 Jan 2011

Magnetic maneuverable capsule safe and well-tolerated in the stomach

A study from researchers in Germany showed that magnetic maneuvering of a modified capsule endoscope in the stomach of healthy volunteers under clinical conditions is safe, well-tolerated, and technically feasible. Maneuverability of the capsule within the stomach was excellent and visualization of the gastric mucosa, the inner lining of the stomach, was satisfactory in the majority of subjects.

19 Jan 2011

New findings show reduced vitamin D absorption in patients with quiescent CD

Researchers from Boston University School of Medicine have for the first time shown that reduced vitamin D absorption in patients with quiescent Crohn's disease may be the cause for their increased risk for vitamin D deficiency.

19 Jan 2011

Milk may reduce risk of bowel cancer: Study

Research by Associate Professor Brian Cox and Dr Mary Jane Sneyd of the Otago University’s Hugh Adam cancer epidemiology unit has shown that New Zealand schoolchildren who drank milk daily significantly reduced their chances of getting bowel cancer as adults.

17 Jan 2011

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Massachusetts General Hospital Cancer Center researchers have discovered a previously unknown feature of common tumor cells - massive overexpression of certain DNA sequences that do not code for proteins.

14 Jan 2011

Scientists demonstrate mechanism that explains why PSA levels promote prostate cancer

Researchers at the Duke Cancer Institute who have been studying prostate cancer cells for decades now think they know why PSA levels reflect cancer progression.

14 Jan 2011

Epigenomics concludes feasibility phase in development of improved product concept for Epi proColon

Epigenomics AG, the cancer molecular diagnostic company, today announced that it has concluded the feasibility phase in the development of an improved product concept for Epi proColon, the Company's DNA methylation-based blood test for assistance in the detection of individuals with colorectal cancer.

13 Jan 2011

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Genomic research could help doctors better target a drug widely used to treat colorectal cancer patients, according to a study by Genomic Health Inc. and the Translational Genomics Research Institute.

13 Jan 2011

Daiichi Sankyo and ArQule initiate enrollment in ARQ 197 Phase 3 trial in NSCLC

Daiichi Sankyo Company, Limited and ArQule, Inc. today announced that the first patient has been enrolled in the Phase 3 trial of ARQ 197, an investigational selective inhibitor of the c-Met receptor tyrosine kinase, in combination with erlotinib, for patients diagnosed with non-squamous, non-small cell lung cancer (NSCLC) who have received one or two prior systemic anti-cancer therapies.

12 Jan 2011

Salix and CCA offer Colonoscopy For Dummies

Salix Pharmaceuticals, Ltd., in partnership with the Colon Cancer Alliance (CCA), is proud to announce the availability of Colonoscopy For Dummies.

12 Jan 2011

Race, ethnicity and geography influence colon cancer screening

New research from UC Davis Cancer Center has found that whether a person gets screened for colon cancer often depends on where they live in addition to their race or ethnicity.

11 Jan 2011

Study to identify early warning biomarkers for presence of breast and prostate cancers

Using biological samples taken from patients and state-of-the-art biochemical techniques, a Florida State University researcher is working to identify a variety of "biomarkers" that might provide earlier warnings of the presence of breast and prostate cancers.

11 Jan 2011

WellApps releases Colonoscopy Prep Assistant

WellApps, LLC, developer of GI Monitor for Crohn's and Ulcerative Colitis, announced today the release of Colonoscopy Prep Assistant. During the portion of colonoscopy preparation when a patient ingests a liquid laxative, Colonoscopy Prep Assistant tracks the number of glasses completed and time between glasses, notifying the patient when it's time to drink their next glass. The app is available for free in iTunes and the Android Market.

11 Jan 2011

New insights into estrogen receptor beta

Research with significant implications in the treatment and intervention of cancer and obesity has been published recently in two prestigious journals by University of Houston (UH) biochemist Dr. Jan--ke Gustafsson.

11 Jan 2011

Genetics Squared to change corporate name to Everist Genomics

Genetics Squared, a prognostics company focused on developing gene-based molecular assays for the prediction of cancer recurrence, today announced that it will change its corporate name to Everist Genomics and has appointed Prasad Sunkara, Ph.D. as its new President and Chief Executive Officer, effective immediately.

10 Jan 2011

Oncolytics opens enrollment in REOLYSIN combination U.S. Phase I colorectal cancer study

Oncolytics Biotech Inc. announced today that a U.S. Phase I study of REOLYSIN® in combination with FOLFIRI (Folinic Acid (leucovorin) + Fluorouracil (5-FU) + Irinotecan) in patients with oxaliplatin refractory/intolerant Kras mutant colorectal cancer (REO 022) is now open to enrollment. The principal investigator is Dr. Sanjay Goel of the Montefiore Medical Center at The Albert Einstein College of Medicine in New York.

10 Jan 2011

Malaria drug makes cancer drug more effective

Scientists investigating the cancer-fighting properties of artesunate - a drug commonly used to treat malaria - have found early evidence that combining it with an existing cancer drug has the potential to make each drug more effective than when used alone. They also found that regular treatment breaks could improve success levels.

7 Jan 2011

Colon News and Research

4SC initiates dosing in resminostat Phase I/II SHORE study for KRAS-mutant colorectal cancer

Data on Ensituximab for treatment of pancreatic and colorectal cancers to be presented at ASCO 2011

Health care reform should mend disconnect between USPSTF recommendations and Medicare coverage

Scripps Research receives NIH grant to develop therapies for circadian rhythm disorders

Magnetic maneuverable capsule safe and well-tolerated in the stomach

New findings show reduced vitamin D absorption in patients with quiescent CD

Milk may reduce risk of bowel cancer: Study

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Scientists demonstrate mechanism that explains why PSA levels promote prostate cancer

Epigenomics concludes feasibility phase in development of improved product concept for Epi proColon

Genomic research could help doctors better target oxaliplatin drug to treat colorectal cancer patients: Study

Daiichi Sankyo and ArQule initiate enrollment in ARQ 197 Phase 3 trial in NSCLC

Salix and CCA offer Colonoscopy For Dummies

Race, ethnicity and geography influence colon cancer screening

Study to identify early warning biomarkers for presence of breast and prostate cancers

WellApps releases Colonoscopy Prep Assistant

New insights into estrogen receptor beta

Genetics Squared to change corporate name to Everist Genomics

Oncolytics opens enrollment in REOLYSIN combination U.S. Phase I colorectal cancer study

Malaria drug makes cancer drug more effective

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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