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Monoclonal antibodies for Alzheimer's offer little benefit, raise safety concerns

Researchers performed a meta-analysis of randomized trial studies that compared the use of amyloid-reducing monoclonal antibodies (MABs) in patients with Alzheimer's dementia at a dose consistent with that used in Phase 3 or FDA approval trials with the use of a placebo.

22 Jan 2024

Study suggests potential overdiagnosis of melanoma in white Americans

More than half of all melanoma diagnoses among white Americans may be overdiagnosed, according to a new study led by a researcher at Dell Medical School at the University of Texas at Austin.

22 Jan 2024

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it's hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

22 Jan 2024

Scientists discover new genetic cause of inherited kidney disease

Genetic changes or mutations can cause hereditary kidney disease, which can eventually lead to dialysis or the need for kidney transplantation. Identifying the cause of inherited kidney disease is the first step in identifying a treatment.

22 Jan 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

WFIRM leads $40M regenerative medicine initiative for the wounded and beyond

The Wake Forest Institute for Regenerative Medicine, part of Wake Forest University School of Medicine, has been selected to lead the Armed Forces Institute of Regenerative Medicine (AFIRM) Consortium.

22 Jan 2024

Early intervention crucial for faster back pain recovery

Low back pain is a major cause of disability around the globe, with more than 570 million people affected.

22 Jan 2024

Thinning brain tissue predicts dementia up to a decade before symptoms

A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.

22 Jan 2024

Unveiling hidden TB risk with cutting-edge techniques

A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.

22 Jan 2024

Receptor protein found to be a key player in prostate cancer cells' drug resistance

Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.

22 Jan 2024

New study examines trends in liquid laundry detergent packet exposures among young children

A new study conducted by researchers at the Center for Injury Research and Policy of the Abigail Wexner Research Institute at Nationwide Children's Hospital and the Central Ohio Poison Center investigated trends in calls to poison centers across the country for exposures to liquid laundry detergent packets.

22 Jan 2024

COMO study focuses on the physical and mental health of children and adolescents in Germany

Less exercise, more time spent in front of screens, higher psychological stress, and reduced physical fitness: These alarming results were obtained by various studies focusing on children and adolescents during the Covid-19 pandemic.

22 Jan 2024

Low-frequency ultrasound influences blood parameters, reserach shows

Research conducted by a team of scientists from Kaunas University, Lithuania, revealed that low-frequency ultrasound influences blood parameters.

22 Jan 2024

Study provides new insights into aging process of the human mind

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has demonstrated that communication among memory-coding neurons - nerve cells in the brain responsible for maintaining working memory - is disrupted with aging and that this can begin in middle age.

22 Jan 2024

Updated pediatric sepsis definition could save countless children's lives

An international research team led by Tell Bennett, MD, MS, professor of biomedical informatics and pediatric critical care at the University of Colorado School of Medicine, released new diagnostic criteria for sepsis in children this week, marking the first update to the pediatric sepsis definition in nearly two decades.

22 Jan 2024

Industrial vegetable oils show dangerous levels of toxic elements, surpassing traditional oils

Evaluation of potentially toxic elements in the vegetable oils traditionally or industrially produced in the Hamadan province of Iran.

22 Jan 2024

Study shows lasting benefits of weight loss and diabetes remission for the heart and kidneys

Researchers in the School of Population Health at RCSI University of Medicine and Health Sciences have provided new evidence of the health benefits of weight loss efforts that lead to diabetes remission for type 2 diabetes patients.

22 Jan 2024

Study: Daily multivitamins hold promise for combating cognitive decline

By 2060, according to the Alzheimer’s Association, nearly one in four Americans will be in an age bracket at elevated risk of cognitive decline and Alzheimer’s disease unless interventions can help preserve cognitive function before deficits begin.

22 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

Study reveals disparities in emergency department restraint use by race and ethnicity

A new study that contributes additional data to a growing body of evidence demonstrating disparities in restraint use in the emergency department (ED) has been published in the January issue of Academic Emergency Medicine (AEM), the peer-reviewed journal of the Society for Academic Emergency Medicine (SAEM).

19 Jan 2024

Medicine News and Research

Monoclonal antibodies for Alzheimer's offer little benefit, raise safety concerns

Study suggests potential overdiagnosis of melanoma in white Americans

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

Scientists discover new genetic cause of inherited kidney disease

Cancer drug holds promise for shrinking polycystic kidney cysts

WFIRM leads $40M regenerative medicine initiative for the wounded and beyond

Early intervention crucial for faster back pain recovery

Thinning brain tissue predicts dementia up to a decade before symptoms

Unveiling hidden TB risk with cutting-edge techniques

Receptor protein found to be a key player in prostate cancer cells' drug resistance

New study examines trends in liquid laundry detergent packet exposures among young children

COMO study focuses on the physical and mental health of children and adolescents in Germany

Low-frequency ultrasound influences blood parameters, reserach shows

Study provides new insights into aging process of the human mind

Updated pediatric sepsis definition could save countless children's lives

Industrial vegetable oils show dangerous levels of toxic elements, surpassing traditional oils

Study shows lasting benefits of weight loss and diabetes remission for the heart and kidneys

Study: Daily multivitamins hold promise for combating cognitive decline

Using AI to break the opioid addiction cycle

Study reveals disparities in emergency department restraint use by race and ethnicity

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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